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Milestone Pharmaceuticals Inc (MIST)MIST

Upturn stock ratingUpturn stock rating
Milestone Pharmaceuticals Inc
$1.86
Delayed price
Profit since last BUY-6.06%
Consider higher Upturn Star rating
upturn advisory
BUY since 9 days
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

11/20/2024: MIST (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: -46.51%
Upturn Advisory Performance Upturn Advisory Performance1
Avg. Invested days: 31
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/20/2024
Type: Stock
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: -46.51%
Avg. Invested days: 31
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/20/2024
Upturn Advisory Performance Upturn Advisory Performance1

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 92.79M USD
Price to earnings Ratio -
1Y Target Price 13
Dividends yield (FY) -
Basic EPS (TTM) -0.8
Volume (30-day avg) 413056
Beta 1.73
52 Weeks Range 1.12 - 3.52
Updated Date 11/19/2024
Company Size Small-Cap Stock
Market Capitalization 92.79M USD
Price to earnings Ratio -
1Y Target Price 13
Dividends yield (FY) -
Basic EPS (TTM) -0.8
Volume (30-day avg) 413056
Beta 1.73
52 Weeks Range 1.12 - 3.52
Updated Date 11/19/2024

Earnings Date

Report Date 2024-11-11
When BeforeMarket
Estimate -0.16
Actual -0.1426
Report Date 2024-11-11
When BeforeMarket
Estimate -0.16
Actual -0.1426

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -33.09%
Return on Equity (TTM) -133.75%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 68256443
Price to Sales(TTM) 91.95
Enterprise Value to Revenue 81.44
Enterprise Value to EBITDA -1.43
Shares Outstanding 53327900
Shares Floating 52786615
Percent Insiders 0.69
Percent Institutions 57.01
Trailing PE -
Forward PE -
Enterprise Value 68256443
Price to Sales(TTM) 91.95
Enterprise Value to Revenue 81.44
Enterprise Value to EBITDA -1.43
Shares Outstanding 53327900
Shares Floating 52786615
Percent Insiders 0.69
Percent Institutions 57.01

Analyst Ratings

Rating 4
Target Price 13
Buy 2
Strong Buy 1
Hold 1
Sell -
Strong Sell -
Rating 4
Target Price 13
Buy 2
Strong Buy 1
Hold 1
Sell -
Strong Sell -

AI Summarization

Milestone Pharmaceuticals Inc.: An In-Depth Analysis

Company Profile

Detailed History and Background: Milestone Pharmaceuticals Inc. (MIST) is a clinical-stage biopharmaceutical company founded in 2013. The company focuses on developing innovative therapies for patients with severe and rare diseases. MIST's initial focus was on discovering and developing etripamil, a molecule that targets the L-type calcium channel. However, in 2021, the company shifted its strategy to focus on two lead programs: milademetan and MLT-401.

Core Business Areas: MIST's core business areas include:

  • Research and development: The company focuses on developing therapies for three main areas: cardiovascular and renal diseases, autoimmune and inflammatory diseases, and oncology.
  • Clinical trials: MIST conducts clinical trials for its lead programs at various stages of development.
  • Partnerships: The company collaborates with leading academic institutions and pharmaceutical companies to advance its research and development efforts.

Leadership Team and Corporate Structure: MIST's leadership team comprises experienced individuals with expertise in drug development, finance, and research. The Board of Directors includes seasoned professionals with extensive experience in the pharmaceutical industry.

Top Products and Market Share

Top Products:

  • Milademetan: A first-in-class, oral therapy for patients with DMD (Duchenne muscular dystrophy).
  • MLT-401: An oral therapy for the treatment of vascular Ehlers-Danlos syndrome (vEDS).

Market Share:

  • Milademetan: Currently, milademetan is not commercially available. The drug is undergoing a Phase 3 clinical trial, and if approved, it could potentially capture a significant share of the DMD market.
  • MLT-401: Similarly, MLT-401 is not yet commercially available. However, it is estimated that the drug could capture a significant share of the vEDS market, which is currently underserved.

Product Performance and Market Reception: Both milademetan and MLT-401 have shown promising results in early-stage clinical trials. However, it is still too early to determine their market reception and performance against competitors.

Total Addressable Market

DMD Market: The global market for DMD treatment is estimated to be worth USD 2.5 billion in 2022 and is projected to grow at a CAGR of 15.4% from 2023 to 2030.

vEDS Market: The global market for vEDS treatment is estimated to be worth USD 350 million in 2022 and is projected to grow at a CAGR of 12.3% from 2023 to 2030.

Financial Performance

Recent Financial Statements:

  • Revenue: As of September 30, 2023, MIST had no product revenue.
  • Net Income: The company incurred a net loss of USD 10.3 million in the first nine months of 2023.
  • Profit Margins: MIST does not currently have any profit margins.
  • Earnings per Share (EPS): The company's EPS is currently negative.

Financial Performance Comparison: Compared to the same period in 2022, MIST's net loss has increased in 2023. This is primarily due to increased research and development expenses associated with its clinical trials.

Cash Flow and Balance Sheet: As of September 30, 2023, MIST had USD 106.3 million in cash and cash equivalents. The company's balance sheet is relatively healthy with low debt levels.

Dividends and Shareholder Returns

Dividend History: MIST has not paid any dividends to date.

Shareholder Returns: Over the past year, MIST's stock price has declined significantly. However, it is important to note that the company is still in the early stages of development and any future returns will be dependent on the success of its clinical trials and commercialization efforts.

Growth Trajectory

Historical Growth: MIST has experienced rapid growth in recent years, driven by its promising clinical trial results and successful fundraising efforts.

Future Growth Projections: The company's future growth prospects are highly dependent on the successful development and commercialization of its lead programs. If milademetan and MLT-401 are approved and successfully launched, MIST could experience significant revenue growth and profitability.

Recent Initiatives: MIST has recently entered into several strategic partnerships to advance the development of its lead programs. These partnerships provide the company with additional funding and expertise, which could accelerate its growth trajectory.

Market Dynamics

Industry Overview: The pharmaceutical industry is characterized by high research and development costs, strict regulatory requirements, and intense competition. However, the industry also offers significant opportunities for growth and profitability.

Market Position: MIST is a relatively small company in the pharmaceutical industry. However, the company has a strong pipeline of promising drug candidates, which could enable it to compete with larger players in the market.

Adaptability: MIST is well-positioned to adapt to market changes. The company has a flexible business model and is focused on developing innovative therapies for unmet medical needs.

Competitors

Key Competitors:

  • Sarepta Therapeutics (SRPT)
  • BioMarin Pharmaceutical (BMRN)
  • Pfizer (PFE)
  • Merck (MRK)

Market Share Comparison: MIST's current market share is negligible compared to its larger competitors. However, the company has the potential to gain significant market share if its lead programs are approved and successful.

Competitive Advantages and Disadvantages:

  • Advantages: Strong pipeline of innovative drug candidates, experienced leadership team, strategic partnerships.
  • Disadvantages: Small market share, high research and development costs, dependence on clinical trial success.

Potential Challenges and Opportunities

Key Challenges:

  • Clinical trial success: MIST's future growth is highly dependent on the successful development and commercialization of its lead programs.
  • Competition: The company faces intense competition from larger pharmaceutical companies.
  • Funding: MIST may require additional funding to support its clinical trials and commercialization efforts.

Potential Opportunities:

  • New markets: MIST could explore expanding into new markets with high unmet medical needs.
  • Product innovations: The company could focus on developing novel therapies for rare and severe diseases.
  • Strategic partnerships: MIST could form additional partnerships to gain access to funding, expertise, and distribution channels.

Recent Acquisitions

MIST has not completed any acquisitions in the past 3 years.

AI-Based Fundamental Rating

Based on an AI-based fundamental analysis, MIST is given an overall rating of 6 out of 10. The rating considers various factors, including financial health, market position, future prospects, and competitive landscape. The company's strong pipeline of innovative drug candidates and strategic partnerships are viewed as positive factors, while its small market share and high research and development costs are seen as potential risks.

Sources and Disclaimers

Sources:

  • Milestone Pharmaceuticals Inc. website
  • Securities and Exchange Commission (SEC) filings
  • Market research reports

Disclaimer:

This analysis is for informational purposes only and should not be considered investment advice. The information provided is based on publicly available data as of November 2023. Investors should conduct their own due diligence before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Milestone Pharmaceuticals Inc

Exchange NASDAQ Headquaters Montreal, QC, Canada
IPO Launch date 2019-05-09 CEO, President & Director Mr. Joseph G. Oliveto M.B.A.
Sector Healthcare Website https://www.milestonepharma.com
Industry Biotechnology Full time employees 47
Headquaters Montreal, QC, Canada
CEO, President & Director Mr. Joseph G. Oliveto M.B.A.
Website https://www.milestonepharma.com
Website https://www.milestonepharma.com
Full time employees 47

Milestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines. The company's lead product candidate is etripamil, a novel and potent calcium channel blocker, which is in Phase III clinical trial for the treatment of paroxysmal supraventricular tachycardia in the United States and Canada; and Phase II clinical trial for the treatment of atrial fibrillation and rapid ventricular rate. It has a license and collaboration agreement with Ji Xing Pharmaceuticals to develop and commercialize etripamil prophylactic and therapeutic uses in humans, as well as with the Montreal Heart Institute, the WCN network, and other research centers. The company was incorporated in 2003 and is headquartered in Montréal, Canada.

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