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Mirum Pharmaceuticals Inc (MIRM)MIRM
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Upturn Advisory Summary
11/20/2024: MIRM (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Historic Profit: -11.07% | Upturn Advisory Performance 3 | Avg. Invested days: 32 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/20/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Historic Profit: -11.07% | Avg. Invested days: 32 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/20/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 2.02B USD |
Price to earnings Ratio - | 1Y Target Price 62.55 |
Dividends yield (FY) - | Basic EPS (TTM) -2.08 |
Volume (30-day avg) 364788 | Beta 1.16 |
52 Weeks Range 23.14 - 48.89 | Updated Date 11/20/2024 |
Company Size Mid-Cap Stock | Market Capitalization 2.02B USD | Price to earnings Ratio - | 1Y Target Price 62.55 |
Dividends yield (FY) - | Basic EPS (TTM) -2.08 | Volume (30-day avg) 364788 | Beta 1.16 |
52 Weeks Range 23.14 - 48.89 | Updated Date 11/20/2024 |
Earnings Date
Report Date 2024-11-04 | When AfterMarket |
Estimate -0.45 | Actual -0.2979 |
Report Date 2024-11-04 | When AfterMarket | Estimate -0.45 | Actual -0.2979 |
Profitability
Profit Margin -32.51% | Operating Margin (TTM) -14.04% |
Management Effectiveness
Return on Assets (TTM) -9.1% | Return on Equity (TTM) -39.84% |
Revenue by Products
Revenue by Products - Current and Previous Year
Revenue by Geography
Valuation
Trailing PE - | Forward PE 59.88 |
Enterprise Value 2021556786 | Price to Sales(TTM) 6.58 |
Enterprise Value to Revenue 6.58 | Enterprise Value to EBITDA -8.85 |
Shares Outstanding 48004600 | Shares Floating 36233858 |
Percent Insiders 2.24 | Percent Institutions 115.67 |
Trailing PE - | Forward PE 59.88 | Enterprise Value 2021556786 | Price to Sales(TTM) 6.58 |
Enterprise Value to Revenue 6.58 | Enterprise Value to EBITDA -8.85 | Shares Outstanding 48004600 | Shares Floating 36233858 |
Percent Insiders 2.24 | Percent Institutions 115.67 |
Analyst Ratings
Rating 4.64 | Target Price 55.43 | Buy 4 |
Strong Buy 7 | Hold - | Sell - |
Strong Sell - |
Rating 4.64 | Target Price 55.43 | Buy 4 | Strong Buy 7 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Mirum Pharmaceuticals Inc.: A Comprehensive Overview
Company Profile:
Detailed history and background:
Mirum Pharmaceuticals Inc. (NASDAQ: MIRM) is a clinical-stage biopharmaceutical company founded in 2016 and headquartered in Foster City, California. The company focuses on discovering, developing, and commercializing novel therapies for patients with genetically defined neurological disorders.
Core business areas:
Mirum primarily concentrates on three key areas:
- Treatment of Orphan Neurological Diseases: Mirum targets rare neurological diseases with high unmet medical needs.
- Genetically Defined Targets: The company focuses on developing therapies based on specific genetic mutations linked to the diseases.
- Precision Medicines: Mirum strives to create effective and well-tolerated treatments with improved patient outcomes.
Leadership team and corporate structure:
Mirum boasts a seasoned leadership team with extensive experience in drug development and commercialization. Key members include:
- Founder and CEO, Richard Peters, M.D.: A veteran in the pharmaceutical industry with over 20 years of experience.
- Chief Medical Officer, William Carroll, M.D.: A renowned neurologist with expertise in rare neurological diseases.
- Chief Financial Officer, Christopher Moreau: A seasoned finance professional with experience in leading public and private companies.
Top Products and Market Share:
Top products and offerings:
Mirum currently has no marketed products as it is still in the development stage. However, its pipeline includes:
- MAR-242: A small molecule in Phase 2 development for the treatment of Angelman syndrome.
- MAR-801: A small molecule in Phase 1 development for the treatment of Rett syndrome.
Market share analysis:
As Mirum has no marketed products, it currently holds no market share. However, the potential markets for its pipeline products are significant:
- Angelman syndrome: Estimated global market size of $1.5 billion by 2027.
- Rett syndrome: Estimated global market size of $1.2 billion by 2027.
Product performance and market reception:
Data on product performance and market reception is unavailable as Mirum has no marketed products. However, early clinical trial results for its pipeline assets have shown promising efficacy and safety profiles.
Total Addressable Market:
The total addressable market (TAM) for Mirum's therapies encompasses the combined market sizes of its target indications. Considering the estimates for Angelman syndrome and Rett syndrome, the TAM could reach $2.7 billion by 2027.
Financial Performance:
Analysis of financial statements:
Mirum is a clinical-stage company with no current product revenue. Its financial statements primarily reflect research and development expenses. In 2022, the company reported a net loss of $106.5 million, primarily driven by R&D investments.
Year-over-year comparison:
Mirum's net loss has increased year-over-year, reflecting its ongoing clinical development activities. However, the company maintains a strong cash position, which should support its operations through 2025.
Cash flow and balance sheet health:
Mirum's cash flow is primarily driven by financing activities. The company raised $285 million through a public offering in 2022, providing ample cash reserves to fund its ongoing operations and clinical trials.
Dividends and Shareholder Returns:
Dividend history:
Mirum is a pre-revenue company and does not currently pay dividends.
Shareholder returns:
Shareholder returns have been negative since the company's IPO in 2022, reflecting the high-risk nature of investing in early-stage biopharmaceutical companies.
Growth Trajectory:
Historical growth analysis:
Mirum has experienced rapid growth in recent years, driven by its focus on developing novel therapies for rare neurological diseases. The company has successfully advanced its pipeline candidates through early-stage clinical trials.
Future growth projections:
Future growth will depend on the success of Mirum's clinical trials and potential regulatory approvals. The company expects to file a New Drug Application (NDA) for MAR-242 in 2024 and for MAR-801 in 2025.
Recent product launches and strategic initiatives:
Mirum has not launched any products yet. However, the company has entered into strategic partnerships with leading academic institutions and pharmaceutical companies to advance its research and development efforts.
Market Dynamics:
Industry overview:
The rare neurological disease market is expected to grow significantly in the coming years, driven by increased awareness, improved diagnosis, and the development of novel therapies.
Mirum's position:
Mirum is well-positioned in this market with its focus on genetically defined targets and its pipeline of promising therapies. The company's leadership team has extensive experience in developing and commercializing successful treatments for rare diseases.
Competitors:
Key competitors:
- BioMarin Pharmaceutical Inc. (BMRN)
- GW Pharmaceuticals PLC (GWPH)
- Ultragenyx Pharmaceutical Inc. (RARE)
Market share and comparison:
Mirum currently has no market share as it has no marketed products. However, the company is competing with established players in the rare neurological disease market.
Competitive advantages:
Mirum's competitive advantages include its focus on genetically defined targets, its experienced leadership team, and its promising pipeline of therapies.
Potential Challenges and Opportunities:
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Mirum Pharmaceuticals Inc
Exchange | NASDAQ | Headquaters | Foster City, CA, United States |
IPO Launch date | 2019-07-18 | CEO & Director | Mr. Christopher Peetz |
Sector | Healthcare | Website | https://www.mirumpharma.com |
Industry | Biotechnology | Full time employees | 311 |
Headquaters | Foster City, CA, United States | ||
CEO & Director | Mr. Christopher Peetz | ||
Website | https://www.mirumpharma.com | ||
Website | https://www.mirumpharma.com | ||
Full time employees | 311 |
Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally. The company is also involved in the commercialization of Cholbam, a cholic acid capsule, which is approved as treatment for pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects and for adjunctive treatment of patients with peroxisomal disorders, including peroxisome biogenesis disorder-Zellweger spectrum disorder and Smith-Lemli-Opitz syndrome; and Chenodal, a tablet, which is approved for the treatment of radiolucent stones in the gallbladder, and under Phase 3 development for the treatment cerebrotendinous xanthomatosis. In addition, it develops Volixibat, an oral and minimally absorbed agent designed to inhibit IBAT, currently under Phase 2b clinical trial for the treatment of adult patients with cholestatic liver diseases. The company was incorporated in 2018 and is headquartered in Foster City, California.
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