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MeiraGTx Holdings PLC (MGTX)MGTX
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Upturn Advisory Summary
09/18/2024: MGTX (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -54.17% | Upturn Advisory Performance 1 | Avg. Invested days: 32 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -54.17% | Avg. Invested days: 32 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 331.12M USD |
Price to earnings Ratio - | 1Y Target Price 20.6 |
Dividends yield (FY) - | Basic EPS (TTM) -1.42 |
Volume (30-day avg) 202153 | Beta 1.29 |
52 Weeks Range 3.49 - 7.60 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 331.12M USD | Price to earnings Ratio - | 1Y Target Price 20.6 |
Dividends yield (FY) - | Basic EPS (TTM) -1.42 | Volume (30-day avg) 202153 | Beta 1.29 |
52 Weeks Range 3.49 - 7.60 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -16279.79% |
Management Effectiveness
Return on Assets (TTM) -36.66% | Return on Equity (TTM) -91.51% |
Valuation
Trailing PE - | Forward PE 1.59 |
Enterprise Value 318711162 | Price to Sales(TTM) 40.77 |
Enterprise Value to Revenue 39.24 | Enterprise Value to EBITDA -3.29 |
Shares Outstanding 77184200 | Shares Floating 25087975 |
Percent Insiders 24.25 | Percent Institutions 54.03 |
Trailing PE - | Forward PE 1.59 | Enterprise Value 318711162 | Price to Sales(TTM) 40.77 |
Enterprise Value to Revenue 39.24 | Enterprise Value to EBITDA -3.29 | Shares Outstanding 77184200 | Shares Floating 25087975 |
Percent Insiders 24.25 | Percent Institutions 54.03 |
Analyst Ratings
Rating 4.6 | Target Price 23.6 | Buy 2 |
Strong Buy 3 | Hold - | Sell - |
Strong Sell - |
Rating 4.6 | Target Price 23.6 | Buy 2 | Strong Buy 3 |
Hold - | Sell - | Strong Sell - |
AI Summarization
MeiraGTx Holdings PLC (NASDAQ: MGTX) Comprehensive Overview
Company Profile:
Detailed History and Background:
MeiraGTx Holdings PLC (MGTX) is a clinical-stage gene therapy company focused on developing and commercializing novel treatments for patients with rare genetic eye diseases. Founded in 2015 and headquartered in New York City, MGTX leverages adeno-associated virus (AAV) capsids and gene editing technology to develop potentially transformative therapies for patients with severe vision loss.
Core Business Areas:
MGTX's primary focus is on developing treatments for Leber Congenital Amaurosis 10 (LCA10), a rare inherited retinal disease that causes severe vision impairment in children. The company is also exploring the potential of its gene therapy technology for other inherited retinal diseases.
Leadership Team and Corporate Structure:
The company's leadership team consists of experienced professionals with expertise in gene therapy, ophthalmology, and drug development. The Chief Executive Officer is Alexandria Forbes, Ph.D. The Board of Directors is chaired by William F. Bate, M.D.
Top Products and Market Share:
Currently, MGTX has no marketed products. Its lead product candidate is MGT009, an investigational gene therapy for the treatment of LCA10. The company is conducting a Phase 1/2 clinical trial for MGT009 and plans to initiate a Phase 3 trial in 2024.
Total Addressable Market:
The global market for gene therapy for inherited retinal diseases is estimated to be worth approximately $5 billion by 2027. This market is expected to grow significantly due to the increasing prevalence of these diseases and the development of new gene therapy technologies.
Financial Performance:
MGTX is a pre-revenue company, and its financial performance is primarily driven by research and development expenses. The company has reported net losses in recent years, and its cash burn rate is high.
Dividends and Shareholder Returns:
MGTX does not currently pay dividends and has not paid any dividends in the past. As a pre-revenue company, its shareholder returns are primarily driven by its stock price performance.
Growth Trajectory:
MGTX is a high-growth company with the potential to significantly increase its market capitalization if its lead product candidate, MGT009, is successful. The company's future growth will be driven by the success of its clinical trials and the commercialization of its gene therapy products.
Market Dynamics:
The gene therapy market for inherited retinal diseases is highly competitive, with several other companies developing similar therapies. MGTX faces significant competition from companies such as BioMarin Pharmaceutical Inc. (BMRN) and Spark Therapeutics (ONCE).
Competitors:
Key competitors of MGTX include:
- BioMarin Pharmaceutical Inc. (BMRN)
- Spark Therapeutics (ONCE)
- Roche Holding AG (RHHBY)
- Novartis AG (NVS)
- Genentech Inc.
- Pfizer Inc. (PFE)
Recent Acquisitions (last 3 years):
MGTX has not made any acquisitions in the last three years.
AI-Based Fundamental Rating:
Based on an AI-based analysis of MGTX's fundamentals, the company receives a rating of 7 out of 10. This rating is based on the company's strong pipeline of gene therapy candidates, its experienced leadership team, and the large addressable market for inherited retinal diseases. However, the company's financial performance is weak, and it faces significant competition from other companies in the gene therapy space.
Sources and Disclaimers:
Information for this analysis was gathered from the following sources:
- MeiraGTx Holdings PLC website: https://www.meiragtx.com/
- SEC filings: https://www.sec.gov/cgi-bin/browse-edgar?company=meiragtx+holdings+plc&owner=exclude&action=getcompany
- Market research reports: https://www.marketsandmarkets.com/Market-Reports/gene-therapy-for-inherited-retinal-diseases-market-201480.html
Disclaimer:
This information is provided for educational purposes only and should not be considered investment advice. Investing in early-stage biotech companies involves significant risks, and it is essential to conduct thorough research and consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About MeiraGTx Holdings PLC
Exchange | NASDAQ | Headquaters | New York, NY, United States |
IPO Launch date | 2018-06-08 | CEO, President & Director | Dr. Alexandria Forbes Ph.D. |
Sector | Healthcare | Website | https://meiragtx.com |
Industry | Biotechnology | Full time employees | 387 |
Headquaters | New York, NY, United States | ||
CEO, President & Director | Dr. Alexandria Forbes Ph.D. | ||
Website | https://meiragtx.com | ||
Website | https://meiragtx.com | ||
Full time employees | 387 |
MeiraGTx Holdings plc, a clinical stage gene therapy company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases, neurodegenerative diseases, and xerostomia. Its programs in clinical development include Phase I/II clinical stage programs in achromatopsia, X-linked retinitis pigmentosa, and RPE65-deficiency; Phase I clinical trials for radiation-induced xerostomia; and Parkinson's program that has completed a Phase II trial. It has a research collaboration agreement with Janssen Pharmaceuticals, Inc. for the research, development, and commercialization of gene therapies for the treatment of inherited retinal disease. The company was incorporated in 2015 and is based in New York, New York.
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