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MDWD 
Mediwound Ltd (MDWD)
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Upturn Advisory Summary
04/01/2025: MDWD (1-star) is currently NOT-A-BUY. Pass it for now.
Upturn Star Rating
Not Recommended Performance
These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.
AI Based Fundamental Rating
Below Average Performance
These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.
Analysis of Past Performance
Type Stock | Historic Profit -73.37% | Avg. Invested days 24 | Today’s Advisory PASS |
Upturn Star Rating | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 04/01/2025 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 179.23M USD | Price to earnings Ratio - | 1Y Target Price 31 |
Price to earnings Ratio - | 1Y Target Price 31 | ||
Volume (30-day avg) 84228 | Beta 0.82 | 52 Weeks Range 12.78 - 24.00 | Updated Date 04/1/2025 |
52 Weeks Range 12.78 - 24.00 | Updated Date 04/1/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.95 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Geography
Earnings Date
Report Date 2025-03-19 | When Before Market | Estimate -0.6075 | Actual -0.36 |
Profitability
Profit Margin -149.46% | Operating Margin (TTM) -104.47% |
Management Effectiveness
Return on Assets (TTM) -17.33% | Return on Equity (TTM) -96.34% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 172210443 | Price to Sales(TTM) 8.86 |
Enterprise Value 172210443 | Price to Sales(TTM) 8.86 | ||
Enterprise Value to Revenue 8.52 | Enterprise Value to EBITDA -6.32 | Shares Outstanding 11251800 | Shares Floating 7322966 |
Shares Outstanding 11251800 | Shares Floating 7322966 | ||
Percent Insiders 18.94 | Percent Institutions 45.74 |
Analyst Ratings
Rating 4.5 | Target Price 29 | Buy 2 | Strong Buy 2 |
Buy 2 | Strong Buy 2 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Mediwound Ltd
Company Overview
History and Background
MediWound Ltd., founded in 2000, is a biopharmaceutical company focused on developing, manufacturing, and commercializing novel, cost-effective bio-therapeutic solutions for severe burns, chronic wounds, and other hard-to-treat wounds. They have evolved from focusing solely on enzymatic debridement to expanding their product pipeline and global reach.
Core Business Areas
- EscharEx: A biological product for non-surgical enzymatic debridement of eschar (dead tissue) in severe burn patients. It reduces the need for surgical interventions.
- NexoBrid: The trade name for EscharEx in Europe and other territories. It is marketed by partners outside of the US.
- MW005: A research and development program targeting biological solutions for treating Non-melanoma skin cancers (NMSC).
Leadership and Structure
MediWound's leadership team includes seasoned executives with experience in the pharmaceutical and biotechnology industries. The organizational structure includes departments for research and development, manufacturing, clinical operations, and commercialization.
Top Products and Market Share
Key Offerings
- NexoBrid/EscharEx: A biological product for non-surgical enzymatic debridement of eschar. While specific global market share data is fragmented and varies by region due to regulatory approvals and market access, it is approved in the US, Europe and other territories. Competitors include traditional surgical debridement and other enzymatic debridement products. Limited market data available.
- MW005: An early-stage product targeting non-melanoma skin cancers (NMSC). No current market share or revenue data available. The competitors are the standard treatments for NMSC which include surgery, radiation and topical treatments. No market data available.
Market Dynamics
Industry Overview
The wound care market is a growing market, driven by an aging population, increasing prevalence of diabetes and obesity, and rising incidence of chronic wounds and burns. The market includes traditional wound care products, advanced wound care products, and biological therapies.
Positioning
MediWound is positioned in the advanced wound care and biologics segment, offering a non-surgical alternative for debridement. Their competitive advantage lies in the potential to reduce surgical interventions and improve patient outcomes.
Total Addressable Market (TAM)
The global wound care market is estimated to be in the billions of dollars. MediWound's TAM is tied to the portion of the market addressable by NexoBrid/EscharEx, which includes severe burns and potentially chronic wounds. Estimates vary, but this portion is significant. The company is positioned to capture a portion of this TAM through market penetration and expansion.
Upturn SWOT Analysis
Strengths
- Novel enzymatic debridement technology
- Potential to reduce surgical interventions
- Approved in US and Europe
- Pipeline of new products (MW005)
Weaknesses
- Reliance on single key product (NexoBrid/EscharEx)
- Dependence on partnerships for commercialization outside the US
- Limited financial resources compared to larger competitors
- Market access challenges and reimbursement hurdles
Opportunities
- Expansion into new geographic markets
- Development of new applications for enzymatic debridement technology
- Strategic partnerships and collaborations
- Positive clinical trial results for MW005
Threats
- Competition from existing and emerging wound care products
- Regulatory hurdles and changes in reimbursement policies
- Clinical trial failures
- Patent expirations
Competitors and Market Share
Key Competitors
- Integra LifeSciences (IART)
- Smith & Nephew (SNN)
- Organogenesis Holdings Inc. (ORGO)
Competitive Landscape
MediWound faces competition from established players with broader product portfolios and greater financial resources. Their advantage lies in their novel technology, but they need to overcome market access challenges.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth has been tied to NexoBrid/EscharEx adoption and sales. Growth trajectory varies depending on market acceptance.
Future Projections: Future growth depends on market penetration, new product development (MW005), and geographic expansion. Analyst estimates are needed to provide specific projections.
Recent Initiatives: Recent initiatives may include clinical trials, regulatory submissions, commercialization efforts, and partnerships.
Summary
MediWound is a biopharmaceutical company with a focus on novel wound care solutions, particularly NexoBrid/EscharEx. While the product offers a non-surgical debridement option with regulatory approvals, the company faces challenges in market penetration and competition. Their dependence on a single product and need for partnerships highlight the need for strategic initiatives. Successful development and commercialization of MW005 will be critical for sustained growth.
Similar Companies
- IART
- SNN
- ORGO
- ARAV
Sources and Disclaimers
Data Sources:
- Company website
- SEC filings
- Industry reports
- Analyst reports (where available)
Disclaimers:
This analysis is based on publicly available information and is not financial advice. Market share data is estimated and may vary. Real-time financial data is required for a more comprehensive analysis.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Mediwound Ltd
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2014-03-20 | CEO - | ||
Sector Healthcare | Industry Biotechnology | Full time employees 111 | Website https://www.mediwound.com |
Full time employees 111 | Website https://www.mediwound.com | ||
MediWound Ltd., a biopharmaceutical company, develops, manufactures, and commercializes novel, bio-therapeutic, and non-surgical solutions for tissue repair and regeneration in the United States and internationally. It markets NexoBrid, a biopharmaceutical product for the removal of eschar, a dead or damaged tissue in patients with deep partial- and full-thickness thermal burns to burn centers and hospitals burn units. The company also develops EscharEx for the treatment of chronic wounds and other hard-to-heal wounds; and MW005, a topically applied biological product candidate to treat non-melanoma skin cancers. MediWound Ltd. was incorporated in 2000 and is headquartered in Yavne, Israel.
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