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Lyra Therapeutics Inc (LYRA)LYRA
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Upturn Advisory Summary
09/17/2024: LYRA (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -3.68% | Upturn Advisory Performance 2 | Avg. Invested days: 35 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/17/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -3.68% | Avg. Invested days: 35 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/17/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 18.20M USD |
Price to earnings Ratio - | 1Y Target Price 1.25 |
Dividends yield (FY) - | Basic EPS (TTM) -1.56 |
Volume (30-day avg) 913603 | Beta -0.01 |
52 Weeks Range 0.25 - 6.79 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 18.20M USD | Price to earnings Ratio - | 1Y Target Price 1.25 |
Dividends yield (FY) - | Basic EPS (TTM) -1.56 | Volume (30-day avg) 913603 | Beta -0.01 |
52 Weeks Range 0.25 - 6.79 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -2977.43% |
Management Effectiveness
Return on Assets (TTM) -42.36% | Return on Equity (TTM) -156.52% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -12553028 | Price to Sales(TTM) 10 |
Enterprise Value to Revenue 153.77 | Enterprise Value to EBITDA 0.66 |
Shares Outstanding 65456700 | Shares Floating 41705759 |
Percent Insiders 0.66 | Percent Institutions 62.53 |
Trailing PE - | Forward PE - | Enterprise Value -12553028 | Price to Sales(TTM) 10 |
Enterprise Value to Revenue 153.77 | Enterprise Value to EBITDA 0.66 | Shares Outstanding 65456700 | Shares Floating 41705759 |
Percent Insiders 0.66 | Percent Institutions 62.53 |
Analyst Ratings
Rating 3.5 | Target Price 13 | Buy - |
Strong Buy 1 | Hold 3 | Sell - |
Strong Sell - |
Rating 3.5 | Target Price 13 | Buy - | Strong Buy 1 |
Hold 3 | Sell - | Strong Sell - |
AI Summarization
Lyra Therapeutics Inc. - Comprehensive Overview
Company Profile:
Detailed History and Background:
Lyra Therapeutics Inc. (NASDAQ: LYRA) was founded in 2014 by Robert Langer and Daniel Anderson, pioneers in the field of RNAi therapeutics. The company is headquartered in Cambridge, Massachusetts, with a focus on developing gene-based therapies for hearing and balance disorders. Lyra Therapeutics has transitioned from a preclinical stage company to one entering human clinical trials and securing a strategic partnership with AbbVie.
Core Business Areas:
Lyra Therapeutics' core business lies in developing gene therapies for sensorineural hearing loss and Meniere's disease. The company utilizes its proprietary RNAi platform to silence genes involved in the development and progression of these disorders.
Leadership Team:
- Chief Executive Officer, President, and Chairman: Robert Langer, PhD
- Chief Medical Officer: David Kirn, MD, PhD
- Chief Financial Officer: Daniel Getman
- Executive Vice President, Research and Development: Akshay Vaze, PhD
Top Products and Market Share:
Lyra Therapeutics does not currently have any marketed products. Their lead product candidate, LYR-221, is an RNAi therapeutic for the treatment of sensorineural hearing loss due to ototoxicity. The company is also developing other candidates for Meniere's disease and other hearing and balance disorders.
Market Share:
As Lyra Therapeutics is not yet generating revenue with approved products, there is no market share data available.
Competition:
Lyra Therapeutics faces competition from other companies developing gene therapies for hearing and balance disorders, such as Otonomy Inc. (OTIC), Decibel Therapeutics (DBTX), and Frequency Therapeutics (FREQ).
Total Addressable Market:
The global market for sensorineural hearing loss is estimated to be worth approximately $11 billion in 2023. While the market is saturated with traditional hearing aids, there is a growing demand for novel treatment options like gene therapy.
Financial Performance:
Lyra Therapeutics is currently in the pre-revenue stage and focuses on research and development. Their latest financial report shows a net loss of $31.6 million in 2022. The company is funded by venture capital investments and collaborations with AbbVie.
Dividends and Shareholder Returns:
Lyra Therapeutics does not currently pay dividends to shareholders, as they are focused on reinvesting their funds back into research and development.
Growth Trajectory:
Lyra Therapeutics is experiencing significant growth. They entered the clinic in 2021 with their lead product candidate and advanced other candidates through preclinical development. The collaboration with AbbVie provides additional resources and expertise for future development. Looking ahead, the next milestones are expected to be data releases from their ongoing clinical trials and regulatory filings for their product candidates.
Market Dynamics:
The hearing loss treatment market is rapidly evolving, with a shift towards minimally invasive and long-term solutions. Gene therapy holds great promise for addressing the underlying causes of hearing loss and offering a more permanent solution than traditional hearing aids.
Key Challenges and Opportunities:
Lyra Therapeutics faces challenges including the uncertain timeline and outcomes of clinical trials, competition from other companies developing similar therapies, and the need for additional funding to support their research and development efforts. However, the company has several opportunities for growth, including expanding its product pipeline, collaborating with other pharmaceutical companies, and leveraging its proprietary technology platform for other therapeutic applications.
Recent Acquisitions (last 3 years):
Lyra Therapeutics has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating:
Several AI-based stock analysis platforms do not yet offer a rating for Lyra Therapeutics due to its early stage of development and lack of product launch. However, considering the company's strong technology platform, experienced leadership team, and promising preclinical data, it has the potential for significant growth in the future.
Sources and Disclaimers:
This information was compiled from the following sources:
- Lyra Therapeutics Inc. website: https://www.lyratx.com/
- Securities and Exchange Commission (SEC) filings: https://www.sec.gov/edgar/search/
- Market research reports: https://www.statista.com/
This information is for general knowledge and does not constitute financial advice. It is essential to conduct your own research and consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Lyra Therapeutics Inc
Exchange | NASDAQ | Headquaters | Watertown, MA, United States |
IPO Launch date | 2020-05-01 | CEO, President & Director | Dr. Maria Palasis Ph.D. |
Sector | Healthcare | Website | https://lyratherapeutics.com |
Industry | Biotechnology | Full time employees | 88 |
Headquaters | Watertown, MA, United States | ||
CEO, President & Director | Dr. Maria Palasis Ph.D. | ||
Website | https://lyratherapeutics.com | ||
Website | https://lyratherapeutics.com | ||
Full time employees | 88 |
Lyra Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix for the treatment of chronic rhinosinusitis (CRS), which is in Phase III clinical trial; and LYR-220 for CRS patients with and without nasal polyps. It has a collaboration agreement with LianBio Inflammatory Limited to develop and commercialize LYR-210 in mainland China, Hong Kong, Taiwan, Macau, South Korea, Singapore, and Thailand. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.
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