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Lexeo Therapeutics, Inc. Common Stock (LXEO)LXEO
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Upturn Advisory Summary
11/20/2024: LXEO (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: 3.27% | Upturn Advisory Performance 5 | Avg. Invested days: 30 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/20/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: 3.27% | Avg. Invested days: 30 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/20/2024 | Upturn Advisory Performance 5 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 254.24M USD |
Price to earnings Ratio - | 1Y Target Price 22.43 |
Dividends yield (FY) - | Basic EPS (TTM) -12.53 |
Volume (30-day avg) 546668 | Beta - |
52 Weeks Range 5.77 - 22.33 | Updated Date 11/13/2024 |
Company Size Small-Cap Stock | Market Capitalization 254.24M USD | Price to earnings Ratio - | 1Y Target Price 22.43 |
Dividends yield (FY) - | Basic EPS (TTM) -12.53 | Volume (30-day avg) 546668 | Beta - |
52 Weeks Range 5.77 - 22.33 | Updated Date 11/13/2024 |
Earnings Date
Report Date 2024-11-13 | When - |
Estimate - | Actual -0.8919 |
Report Date 2024-11-13 | When - | Estimate - | Actual -0.8919 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -39.93% | Return on Equity (TTM) -74.83% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 52440000 | Price to Sales(TTM) - |
Enterprise Value to Revenue 416.34 | Enterprise Value to EBITDA -6.02 |
Shares Outstanding 33061000 | Shares Floating 16976826 |
Percent Insiders 0.49 | Percent Institutions 91.48 |
Trailing PE - | Forward PE - | Enterprise Value 52440000 | Price to Sales(TTM) - |
Enterprise Value to Revenue 416.34 | Enterprise Value to EBITDA -6.02 | Shares Outstanding 33061000 | Shares Floating 16976826 |
Percent Insiders 0.49 | Percent Institutions 91.48 |
Analyst Ratings
Rating 4.57 | Target Price 20.8 | Buy 3 |
Strong Buy 4 | Hold - | Sell - |
Strong Sell - |
Rating 4.57 | Target Price 20.8 | Buy 3 | Strong Buy 4 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Lexeo Therapeutics, Inc. Common Stock: A Comprehensive Overview
Company Profile
Detailed History and Background:
Lexeo Therapeutics, Inc. (NASDAQ: LXRX) is a clinical-stage pharmaceutical company engaged in the development and commercialization of innovative therapies for the treatment of metabolic diseases. Founded in 2013, Lexeo has its headquarters in Waltham, Massachusetts, and focuses on developing oral therapies for patients with Non-alcoholic Steatohepatitis (NASH) and Type 2 Diabetes (T2D).
Core Business Areas:
- NASH: Lexeo's lead program is LX1031, a highly selective small molecule inhibitor of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) for the treatment of NASH.
- T2D: The company is also developing LX1033, a next-generation GPBAR1 antagonist for the treatment of T2D.
- GLP-1 Receptor Agonist (GLP-1 RA) Program: Lexeo has an ongoing research collaboration with Boehringer Ingelheim to discover and develop novel GLP-1 receptor agonists for the treatment of T2D.
Leadership Team and Corporate Structure:
- Dr. Michael Grey, CEO and Chairman: Dr. Grey has over 25 years of experience in the pharmaceutical industry, having held leadership positions at multiple companies.
- Dr. David Melia, Chief Medical Officer: Dr. Melia has over 20 years of experience in clinical development and regulatory affairs.
- Dr. Christopher Lyttle, Chief Scientific Officer: Dr. Lyttle has over 20 years of experience in drug discovery and development.
Top Products and Market Share
Top Products:
- LX1031: This drug candidate is currently in Phase 3 clinical development for the treatment of NASH.
- LX1033: This drug candidate is in preclinical development for the treatment of T2D.
Market Share:
- NASH: As a company with a drug candidate in Phase 3, Lexeo does not currently hold market share in the NASH market. However, the global NASH market is estimated to reach over $42 billion by 2030.
- T2D: Similarly, Lexeo does not currently have market share in the T2D market. The global T2D market is estimated to reach over $62 billion by 2030.
Comparison with Competitors:
- NASH: Key competitors in the NASH space include Intercept Pharmaceuticals (ICPT), Genfit (GNFT), and Madrigal Pharmaceuticals (MDGL).
- T2D: Major competitors in the T2D market include Novo Nordisk (NVO), Eli Lilly (LLY), and Sanofi (SNY).
Total Addressable Market
The total addressable market for Lexeo's products includes all patients with NASH and T2D worldwide. The global market for these conditions is estimated to be worth over $100 billion by 2030.
Financial Performance
Financial Statements:
- Revenue: Lexeo had no product sales in 2022 or 2021.
- Net Income: The company reported net losses of $43.5 million and $45.4 million in 2022 and 2021, respectively.
- Profit Margins: Lexeo does not currently generate any profit margins.
- Earnings Per Share (EPS): The company reported negative EPS in 2022 and 2021.
Year-over-Year Financial Performance:
Lexeo's revenue and net income have remained relatively consistent over the past two years. However, the company's losses have increased slightly from 2021 to 2022.
Cash Flow and Balance Sheet Health:
Lexeo had $142.5 million in cash and cash equivalents as of December 31, 2022. The company's balance sheet appears healthy, with total assets exceeding total liabilities.
Dividends and Shareholder Returns
Dividend History:
Lexeo does not currently pay dividends to shareholders.
Shareholder Returns:
The company's stock has declined significantly over the past year, with total shareholder returns of approximately -80%.
Growth Trajectory
Historical Growth:
Lexeo has experienced modest revenue growth over the past five years, primarily driven by research and development expenses.
Future Growth Projections:
The company's future growth trajectory depends on the success of its clinical trials and regulatory approvals. If Lexeo's drug candidates are successful, the company could experience significant revenue growth in the coming years.
Recent Product Launches and Strategic Initiatives:
Lexeo has no recent product launches. However, the company recently initiated a Phase 3 clinical trial for LX1031 for the treatment of NASH.
Market Dynamics
Industry Trends:
The NASH and T2D markets are expected to experience strong growth in the coming years due to the rising prevalence of these conditions globally.
Competitive Landscape:
The NASH and T2D markets are highly competitive, with several major pharmaceutical companies developing new therapies. Lexeo's success will depend on its ability to differentiate its products from competitors and demonstrate clinical efficacy.
Key Competitors
- NASH: Intercept Pharmaceuticals (ICPT), Genfit (GNFT), Madrigal Pharmaceuticals (MDGL), Gilead Sciences (GILD), Novo Nordisk (NVO).
- T2D: Novo Nordisk (NVO), Eli Lilly (LLY), Sanofi (SNY), Boehringer Ingelheim (BHR).
Potential Challenges and Opportunities
Key Challenges:
- Clinical Trial Results: The success of Lexeo's clinical trials is crucial for the company's future growth. Any setbacks in trials could delay or derail the company's plans.
- Competition: The intensely competitive nature of the NASH and T2D markets could make it difficult for Lexeo to gain market share.
- Regulatory Approval: Obtaining regulatory approval for the company's drug candidates is a complex and time-consuming process.
Potential Opportunities:
- NASH Market Growth: The growing prevalence of NASH presents a significant opportunity for Lexeo, as the company seeks to position LX1031 as a leading treatment option.
- Strategic Partnerships: Collaborations with other pharmaceutical companies could help Lexeo accelerate the development and commercialization of its products.
- Technological Advancements: Lexeo is actively exploring new technologies to improve its drug discovery and development processes, which could lead to further breakthroughs.
Recent Acquisitions (last 3 years):
Lexeo has not made any acquisitions in the past three years.
AI-Based Fundamental Rating
Rating: 6 out of 10
Justification:
- Financial Health: Lexeo is currently not profitable, but it has a healthy cash balance and a strong balance sheet.
- Market Position: The company has promising drug candidates in development for large market opportunities, but it faces stiff competition.
- Future Prospects: Lexeo's future growth depends on the success of its clinical trials and regulatory approvals. However, the company has a promising pipeline and a strong management team.
Sources and Disclaimers
Sources:
- Lexeo Therapeutics, Inc. website
- Bloomberg Terminal
- Yahoo Finance
Disclaimers:
- This analysis is for informational purposes only and should not be considered investment advice.
- The information provided in this analysis is based on publicly available data and may not be entirely accurate.
- Investors should conduct their own research before making any investment decisions.
Conclusion
Lexeo Therapeutics is a clinical-stage pharmaceutical company with a promising pipeline of drug candidates for the treatment of NASH and T2D. The company faces numerous challenges, but it also has significant potential for growth. Investors should carefully consider the risks and rewards before investing in Lexeo Therapeutics.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Lexeo Therapeutics, Inc. Common Stock
Exchange | NASDAQ | Headquaters | New York, NY, United States |
IPO Launch date | 2023-11-03 | CEO & Director | Mr. R. Nolan Townsend |
Sector | Healthcare | Website | https://www.lexeotx.com |
Industry | Biotechnology | Full time employees | 69 |
Headquaters | New York, NY, United States | ||
CEO & Director | Mr. R. Nolan Townsend | ||
Website | https://www.lexeotx.com | ||
Website | https://www.lexeotx.com | ||
Full time employees | 69 |
Lexeo Therapeutics, Inc. operates as a clinical stage genetic medicine company that focuses on hereditary and acquired diseases. The company develops LX2006, which is an AAVrh10-based gene therapy candidate for the treatment of Friedreich's ataxia (FA) cardiomyopathy; LX2020, an AAVrh10-based gene therapy candidate for the treatment of plakophilin-2 arrhythmogenic cardiomyopathy; LX2021, a gene therapy candidate for the treatment of DSP cardiomyopathy associated with it; and LX2022, a gene therapy candidate for the treatment of hypertrophic cardiomyopathy, or HCM caused by TNNI3 gene. It also develops LX1001, an AAVrh10-based gene therapy candidate for the treatment of APOE4 homozygous; LX1020, a gene therapy candidate for the treatment of APOE4 homozygous; LX1021 for the treatment of APOE4 homozygotes; and LX1004 for the treatment of CLN2 Batten disease. The company was incorporated in 2017 and is based in New York, New York.
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