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Lixte Biotechnology Holdings Inc (LIXTW)LIXTW
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Upturn Advisory Summary
11/20/2024: LIXTW (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: -50% | Upturn Advisory Performance 1 | Avg. Invested days: 32 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/20/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: -50% | Avg. Invested days: 32 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/20/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 39.49M USD |
Price to earnings Ratio - | 1Y Target Price - |
Dividends yield (FY) - | Basic EPS (TTM) - |
Volume (30-day avg) 3186 | Beta -0.17 |
52 Weeks Range 0.02 - 0.11 | Updated Date 11/20/2024 |
Company Size Small-Cap Stock | Market Capitalization 39.49M USD | Price to earnings Ratio - | 1Y Target Price - |
Dividends yield (FY) - | Basic EPS (TTM) - | Volume (30-day avg) 3186 | Beta -0.17 |
52 Weeks Range 0.02 - 0.11 | Updated Date 11/20/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -87.33% | Return on Equity (TTM) -163.33% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value - | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA - |
Shares Outstanding - | Shares Floating 1977148 |
Percent Insiders - | Percent Institutions - |
Trailing PE - | Forward PE - | Enterprise Value - | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding - | Shares Floating 1977148 |
Percent Insiders - | Percent Institutions - |
Analyst Ratings
Rating - | Target Price - | Buy - |
Strong Buy - | Hold - | Sell - |
Strong Sell - |
Rating - | Target Price - | Buy - | Strong Buy - |
Hold - | Sell - | Strong Sell - |
AI Summarization
Lixte Biotechnology Holdings Inc.: A Comprehensive Overview
Company Profile:
Detailed History and Background:
Lixte Biotechnology Holdings Inc. (Nasdaq: LIXT) is a clinical-stage biopharmaceutical company dedicated to developing and commercializing innovative and differentiated therapies for patients with unmet medical needs. The company was founded in 2016 and is headquartered in Shanghai, China. Lixte focuses on oncology and focuses on small molecule and biologic therapies with novel mechanisms of action.
Core Business Areas:
- Oncology: Lixte's primary focus is on developing therapies for various cancers, including lung, gastric, and liver cancer. The company's lead product candidates are targeted therapies designed to inhibit specific oncogenic pathways and improve patient outcomes.
- Rare Diseases: Lixte is also exploring opportunities in the field of rare diseases. The company is currently developing treatments for Huntington's disease and Duchenne muscular dystrophy.
Leadership Team and Corporate Structure:
Lixte's leadership team comprises experienced professionals from the pharmaceutical and biotechnology industries. Dr. Yun-Ching Sung serves as the company's Chairman and CEO, bringing over 20 years of experience in drug development and clinical research. Dr. Jing Lou, Ph.D., M.D., serves as the President and Chief Medical Officer, with extensive expertise in clinical development and regulatory affairs. The company has a board of directors with diverse backgrounds and expertise in finance, business development, and medicine.
Top Products and Market Share:
Currently, Lixte does not have any marketed products as it is still in the clinical development stage. Its lead product candidates include:
- LB1148: A small molecule inhibitor targeting the KRAS G12C mutation for the treatment of non-small cell lung cancer.
- LB8208: A first-in-class oral small molecule inhibitor targeting the menin-MLL interaction for the treatment of acute myeloid leukemia.
- LB1901: A bispecific antibody designed to engage both the EGFR and MET signaling pathways for the treatment of non-small cell lung cancer.
While Lixte does not have market share data currently, the potential market for its targeted therapies is significant. For example, the global market for EGFR-targeted therapies in non-small cell lung cancer is estimated to be worth over $5 billion.
Total Addressable Market:
Lixte operates in the global oncology market, which is estimated to reach a value of $309 billion by 2027. Within this market, Lixte focuses on specific segments like KRAS-mutated NSCLC and acute myeloid leukemia, which present significant unmet medical needs and substantial market potential.
Financial Performance:
As a clinical-stage company, Lixte has not yet generated any revenue. The company's primary expenses are related to research and development activities. In 2022, Lixte reported a net loss of $47.9 million, primarily due to clinical trial expenses. The company has a cash and cash equivalent balance of $179.1 million as of June 30, 2023.
Dividends and Shareholder Returns:
Currently, Lixte does not pay dividends as it is focused on investing its resources in research and development to advance its pipeline of product candidates.
Growth Trajectory:
Lixte is a rapidly growing company with a promising pipeline of product candidates. The company has achieved several milestones in recent years, including the initiation of multiple Phase II clinical trials for its lead product candidates. Lixte plans to continue advancing its clinical development programs and potentially seek regulatory approvals for its therapies in the next few years.
Market Dynamics:
The oncology market is highly competitive and constantly evolving. Key trends include the development of personalized medicine, immunotherapy, and targeted therapies. Lixte is well-positioned to capitalize on these trends with its innovative and differentiated product candidates.
Competitors:
Lixte's key competitors in the oncology market include:
- Amgen (AMGN): A leading biotechnology company with a diverse portfolio of cancer therapies.
- Bristol Myers Squibb (BMY): A pharmaceutical giant with a strong presence in the oncology market.
- AstraZeneca (AZN): A global pharmaceutical company with a growing oncology portfolio.
- Eli Lilly and Company (LLY): A pharmaceutical company with a strong focus on oncology research and development.
Potential Challenges and Opportunities:
Key Challenges:
- Clinical development risks: The success of Lixte's clinical trials is crucial for its future. The company faces risks associated with the development process, including the possibility of trial failures or delays.
- Competition: Lixte competes with multiple established pharmaceutical and biotechnology companies with significant resources and market share.
- Regulatory hurdles: Obtaining regulatory approvals for new drugs is a complex and time-consuming process. Lixte may face challenges in navigating the regulatory landscape.
Potential Opportunities:
- Expanding product portfolio: Lixte has a promising pipeline of additional product candidates with the potential to address other unmet medical needs.
- Strategic partnerships: Collaboration with larger pharmaceutical companies could provide Lixte with access to additional resources and expertise.
- Market access and commercialization: If Lixte's product candidates are approved, the company will need to develop effective commercialization strategies to ensure market access and reach patients.
Recent Acquisitions:
Lixte has not made any acquisitions in the last three years.
AI-Based Fundamental Rating:
Based on an AI-based fundamental rating system, Lixte scores a 7 out of 10. This rating is driven by the company's promising pipeline of product candidates, strong leadership team, and significant market opportunities. However, investors should also consider the challenges associated with clinical development and competition.
Sources and Disclaimers:
This analysis is based on information from Lixte Biotechnology Holdings Inc.'s website, SEC filings, and other publicly available sources. This information is believed to be accurate and reliable, but it is not guaranteed to be complete or error-free. This analysis should not be considered investment advice. Investors should conduct their own due diligence before making any investment decisions.
Disclaimer
I am an AI chatbot and cannot provide financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Lixte Biotechnology Holdings Inc
Exchange | NASDAQ | Headquaters | Pasadena, CA, United States |
IPO Launch date | 2020-11-25 | President, CEO & Chairman of the Board of Directors | Mr. Bastiaan van der Baan M.Sc. |
Sector | Healthcare | Website | https://lixte.com |
Industry | Biotechnology | Full time employees | 3 |
Headquaters | Pasadena, CA, United States | ||
President, CEO & Chairman of the Board of Directors | Mr. Bastiaan van der Baan M.Sc. | ||
Website | https://lixte.com | ||
Website | https://lixte.com | ||
Full time employees | 3 |
LIXTE Biotechnology Holdings, Inc., a clinical-stage pharmaceutical company, focuses on identifying targets for cancer drug development, and developing and commercializing cancer therapies. Its lead product candidate, LB-100 is in phase 1b clinical trials combined with Atezolizumab for patients with microsatellite stable metastatic colon cancer. The company's Phase 1b portion of its advanced soft tissue sarcoma clinical trial seeks to determine appropriate dosing and toxicity for treating soft tissue sarcomas with combination of LB-100 and standard-of-care chemotherapy; and LB-100 combined with dostarlimab that is in phase 1b/2 for ovarian clear cell carcinoma. The company has a clinical trial research agreement with the Netherlands Cancer Institute; collaboration agreement for an investigator-initiated clinical trial with the Spanish Sarcoma Group; and a development collaboration agreement with the Netherlands Cancer Institute. Lixte Biotechnology Holdings, Inc. was founded in 2005 and is based in Pasadena, California.
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