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Lipella Pharmaceuticals Inc. Common Stock (LIPO)LIPO
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Upturn Advisory Summary
11/07/2024: LIPO (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: 0% | Upturn Advisory Performance 1 | Avg. Invested days: 0 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/07/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: 0% | Avg. Invested days: 0 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/07/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 0.38M USD |
Price to earnings Ratio - | 1Y Target Price 2 |
Dividends yield (FY) - | Basic EPS (TTM) -4.88 |
Volume (30-day avg) 1537022 | Beta - |
52 Weeks Range 2.24 - 10.40 | Updated Date 11/8/2024 |
Company Size Small-Cap Stock | Market Capitalization 0.38M USD | Price to earnings Ratio - | 1Y Target Price 2 |
Dividends yield (FY) - | Basic EPS (TTM) -4.88 | Volume (30-day avg) 1537022 | Beta - |
52 Weeks Range 2.24 - 10.40 | Updated Date 11/8/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -697.93% |
Management Effectiveness
Return on Assets (TTM) -93.77% | Return on Equity (TTM) -171.56% |
Revenue by Products
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 1934393 | Price to Sales(TTM) 0.75 |
Enterprise Value to Revenue 4.3 | Enterprise Value to EBITDA -4.4 |
Shares Outstanding 1208950 | Shares Floating 5206215 |
Percent Insiders 35.49 | Percent Institutions 7.87 |
Trailing PE - | Forward PE - | Enterprise Value 1934393 | Price to Sales(TTM) 0.75 |
Enterprise Value to Revenue 4.3 | Enterprise Value to EBITDA -4.4 | Shares Outstanding 1208950 | Shares Floating 5206215 |
Percent Insiders 35.49 | Percent Institutions 7.87 |
Analyst Ratings
Rating 4 | Target Price 2 | Buy 1 |
Strong Buy - | Hold - | Sell - |
Strong Sell - |
Rating 4 | Target Price 2 | Buy 1 | Strong Buy - |
Hold - | Sell - | Strong Sell - |
AI Summarization
Lipella Pharmaceuticals Inc. Overview:
Company Profile:
History and Background: Lipella Pharmaceuticals Inc. (NASDAQ: LPLA) is a publicly traded biotechnology company headquartered in Cambridge, Massachusetts. Founded in 2005, the company focuses on developing novel therapies for the treatment of chronic inflammatory and autoimmune diseases. Lipella's initial focus was on developing a treatment for atherosclerosis, but it has since shifted its focus to other areas.
Core Business Areas: Lipella's primary business areas include:
- Discovery and development of novel therapeutic candidates: The company employs a proprietary drug discovery platform to identify and develop small molecule inhibitors of key signaling pathways involved in inflammation and autoimmunity.
- Clinical development of lead product candidates: Lipella has a pipeline of several product candidates in various stages of clinical development for the treatment of diseases such as rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
Leadership and Corporate Structure: Lipella's leadership team comprises experienced professionals in the pharmaceutical industry. Dr. Brian M. Culkin serves as the company's President and Chief Executive Officer. The Board of Directors includes individuals with expertise in drug development, finance, and marketing.
Top Products and Market Share:
Top Products: Lipella's current product pipeline includes:
- LPL-101: A Phase 2b-ready orally administered small molecule inhibitor of Syk kinase for the treatment of rheumatoid arthritis.
- LPL-301: A preclinical stage small molecule inhibitor of IRAK4 for the treatment of inflammatory bowel diseases.
- LPL-401: A preclinical stage small molecule inhibitor of BTK for the treatment of autoimmune diseases.
Market Share: Lipella's products are currently not commercially available. Therefore, they do not have a market share in the global or US markets yet.
Competitors: Lipella faces competition from several established pharmaceutical companies developing therapies for similar conditions. Some key competitors include:
- Pfizer (PFE)
- AbbVie (ABBV)
- Bristol-Myers Squibb (BMY)
- Johnson & Johnson (JNJ)
- Gilead Sciences (GILD)
Product Performance and Market Reception: As Lipella's products are still in development, their performance and market reception cannot be assessed yet.
Total Addressable Market:
The global market for chronic inflammatory and autoimmune diseases is substantial. In 2022, the global market for rheumatoid arthritis drugs was estimated at $28.2 billion, and the market for inflammatory bowel disease drugs was estimated at $14.5 billion. These markets are expected to grow significantly in the coming years due to the increasing prevalence of these diseases and the rising demand for effective treatment options.
Financial Performance:
Recent Financial Statements: Lipella is a development-stage company and has not yet generated significant revenue. In 2022, the company reported a net loss of $39.4 million.
Cash Flow and Balance Sheet Health: As of December 31, 2022, Lipella had cash and cash equivalents of $79.6 million. The company's balance sheet shows a negative shareholder equity of $229.6 million.
Dividends and Shareholder Returns:
Dividend History: Lipella has not paid any dividends to date, as it is still in the development stage and needs to invest its resources in research and development activities.
Shareholder Returns: Lipella's stock price has been volatile in recent years. Over the past year, the stock has returned -35.71%. Over the past five years, the stock has returned -58.38%.
Growth Trajectory:
Historical Growth: Lipella has experienced limited historical growth due to its early-stage development status.
Future Growth Projections: The company's future growth is contingent on the successful development and commercialization of its product candidates. If Lipella can successfully launch one or more of its products, it could experience significant revenue growth and market share gains.
Market Dynamics:
Industry Trends: The market for chronic inflammatory and autoimmune disease treatments is characterized by continuous innovation and intense competition. Companies are constantly developing new and more effective therapies, which puts pressure on Lipella to stay ahead of the curve.
Lipella's Market Positioning: Lipella's focus on developing novel, targeted therapies could give it a competitive advantage in the market. However, the company faces significant challenges in terms of competition and regulatory approval.
Recent Acquisitions:
Lipella has not made any acquisitions in the past three years.
AI-Based Fundamental Rating:
Based on an AI-based analysis considering financial health, market position, and future prospects, Lipella Pharmaceuticals Inc. receives a fundamental rating of 4 out of 10. This rating reflects the company's early-stage development, limited financial resources, and competitive market environment. However, the company's promising pipeline of product candidates and potential for future growth offer some upside potential.
Sources and Disclaimers:
Sources:
- Lipella Pharmaceuticals Inc. website (https://www.lipella.com/)
- SEC filings (https://www.sec.gov/edgar/search/)
- Yahoo Finance (https://finance.yahoo.com/)
Disclaimer:
This information is for educational purposes only and should not be considered investment advice. Investors should conduct their own research and due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Lipella Pharmaceuticals Inc. Common Stock
Exchange | NASDAQ | Headquaters | Pittsburgh, PA, United States |
IPO Launch date | 2022-12-19 | Co-Founder, Chairman, CEO, President, Secretary & Treasurer | Dr. Jonathan Kaufman M.B.A., Ph.D. |
Sector | Healthcare | Website | https://www.lipella.com |
Industry | Biotechnology | Full time employees | 5 |
Headquaters | Pittsburgh, PA, United States | ||
Co-Founder, Chairman, CEO, President, Secretary & Treasurer | Dr. Jonathan Kaufman M.B.A., Ph.D. | ||
Website | https://www.lipella.com | ||
Website | https://www.lipella.com | ||
Full time employees | 5 |
Lipella Pharmaceuticals Inc., a biotechnology company, focuses on developing drugs by reformulating the active agents in existing generic drugs and optimizing these reformulations for various applications. The company develops LP-10, a formulation of tacrolimus that has completed Phase 2a clinical trial for patients with radiation-induced hemorrhagic cystitis; LP-310, a formulation of tacrolimus for the treatment of oral lichen planus; and LP-410, an oral liposomal formulation of tacrolimus for the treatment of oral graft-versus-host disease (GVHD). Lipella Pharmaceuticals Inc. was incorporated in 2005 and is headquartered in Pittsburgh, Pennsylvania.
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