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Longeveron LLC (LGVN)LGVN

Upturn stock ratingUpturn stock rating
Longeveron LLC
$1.85
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
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Time period over

Upturn Advisory Summary

11/20/2024: LGVN (1-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: -92.11%
Upturn Advisory Performance Upturn Advisory Performance1
Avg. Invested days: 37
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/20/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: -92.11%
Avg. Invested days: 37
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/20/2024
Upturn Advisory Performance Upturn Advisory Performance1

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 27.45M USD
Price to earnings Ratio -
1Y Target Price 8.5
Dividends yield (FY) -
Basic EPS (TTM) -5.62
Volume (30-day avg) 633070
Beta 0.35
52 Weeks Range 0.77 - 23.90
Updated Date 11/19/2024
Company Size Small-Cap Stock
Market Capitalization 27.45M USD
Price to earnings Ratio -
1Y Target Price 8.5
Dividends yield (FY) -
Basic EPS (TTM) -5.62
Volume (30-day avg) 633070
Beta 0.35
52 Weeks Range 0.77 - 23.90
Updated Date 11/19/2024

Earnings Date

Report Date 2024-11-13
When -
Estimate -0.4433
Actual -0.34
Report Date 2024-11-13
When -
Estimate -0.4433
Actual -0.34

Profitability

Profit Margin -
Operating Margin (TTM) -747.86%

Management Effectiveness

Return on Assets (TTM) -62.24%
Return on Equity (TTM) -142.16%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 6269033
Price to Sales(TTM) 22.33
Enterprise Value to Revenue 16.58
Enterprise Value to EBITDA -49.61
Shares Outstanding 13352800
Shares Floating 11186177
Percent Insiders 10.7
Percent Institutions 3.34
Trailing PE -
Forward PE -
Enterprise Value 6269033
Price to Sales(TTM) 22.33
Enterprise Value to Revenue 16.58
Enterprise Value to EBITDA -49.61
Shares Outstanding 13352800
Shares Floating 11186177
Percent Insiders 10.7
Percent Institutions 3.34

Analyst Ratings

Rating 4
Target Price 11.15
Buy 2
Strong Buy -
Hold -
Sell -
Strong Sell -
Rating 4
Target Price 11.15
Buy 2
Strong Buy -
Hold -
Sell -
Strong Sell -

AI Summarization

Longeveron LLC: A Comprehensive Overview

Company Profile:

Detailed History and Background:

Founded in 2014 and headquartered in Miami, Florida, Longeveron LLC is a clinical-stage biotechnology company focused on developing cellular therapies for aging-related diseases. The company originated from research conducted at Mayo Clinic and Buck Institute for Research on Aging. It completed its initial public offering (IPO) on the Nasdaq Stock Market in May 2021.

Core Business Areas:

Longeveron's core business revolves around developing and commercializing cell-based therapies using human mesenchymal stem cells (MSCs). These therapies are designed to treat conditions associated with aging, including:

  • Age-related macular degeneration (AMD)
  • Heart failure
  • Chronic kidney disease
  • Osteoarthritis
  • Pulmonary fibrosis

Leadership Team and Corporate Structure:

Longeveron is led by a team of experienced professionals with expertise in biopharmaceutical development and commercialization. Key members include:

  • Dr. Joshua Hare, Chief Executive Officer and President, brings extensive experience in stem cell research and clinical development.
  • Dr. Michael West, Chief Scientific Officer, has a proven track record in biotechnology research and drug discovery.
  • Mr. Robert Zerman, Chief Financial Officer, possesses strong financial leadership and public company experience.

The company has a Board of Directors composed of independent and industry-experienced individuals who provide strategic guidance and oversight.

Top Products and Market Share:

Top Products:

Longeveron's lead product is Lomecel-B, an allogeneic MSC therapy currently undergoing Phase III clinical trials for the treatment of AMD. Other promising products in their pipeline include:

  • Lomecel-V, for the treatment of heart failure
  • Lomecel-K, for the treatment of chronic kidney disease
  • C-Cure, an autologous MSC therapy for cartilage repair in osteoarthritis

Market Share:

While Longeveron's products are still in the clinical trial stage, the company aims to capture a significant market share in the growing cellular therapy market. The global cell therapy market is expected to reach USD 26.4 billion by 2027, with ophthalmology and cardiology segments representing major growth areas.

Comparison to Competitors:

Longeveron faces competition from other companies developing MSC therapies and established players in the respective disease areas. Key competitors include:

  • Mesoblast (MESO)
  • Athersys (ATHX)
  • Osiris Therapeutics (OSIR)
  • Novartis (NVS)
  • Roche (RHHBY)

Longeveron differentiates itself through its proprietary allogeneic MSC platform, which offers advantages in scalability and cost-effectiveness compared to autologous therapies.

Total Addressable Market:

The total addressable market (TAM) for Longeveron's products encompasses several large and growing markets:

  • AMD: Approximately 196 million people worldwide suffer from AMD.
  • Heart Failure: Over 26 million people globally have heart failure.
  • Chronic Kidney Disease: More than 850 million individuals globally are affected by chronic kidney disease.
  • Osteoarthritis: Affecting an estimated 300 million people worldwide.

Penetrating these substantial markets holds significant potential for Longeveron's future growth.

Financial Performance:

Revenue and Earnings:

As a clinical-stage company, Longeveron currently has limited revenue. In 2022, the company reported a net loss of USD 48.4 million, primarily due to research and development expenses.

Profit Margins:

With no commercialized products, Longeveron does not currently generate profit margins. The company's primary focus is on advancing its clinical pipeline, and profitability is expected to improve with product approvals and commercialization.

Cash Flow and Balance Sheet:

As of December 31, 2022, Longeveron had cash and cash equivalents of USD 30.3 million. The company's balance sheet shows a high dependence on external financing to support its ongoing operations.

Dividends and Shareholder Returns:

Longeveron is a young company focused on growth and does not currently pay dividends. Shareholder returns have been negative since the IPO due to the company's developmental stage and clinical trial costs.

Growth Trajectory:

Historical Growth:

Longeveron has experienced rapid growth in recent years, primarily due to increased investments in research and development and its successful IPO.

Future Growth Projections:

The company's future growth depends on the successful development and commercialization of its cell therapy pipeline. Several analysts project significant revenue growth for Longeveron within the next five years, fueled by potential FDA approvals and product launches.

Market Dynamics:

The market for cell therapies is rapidly evolving, driven by technological advancements and increasing demand for innovative treatment options. Longeveron is well-positioned to capitalize on these trends with its allogeneic MSC platform and promising clinical pipeline.

Competitors:

As mentioned previously, Longeveron's key competitors include Mesoblast (MESO), Athersys (ATHX), Osiris Therapeutics (OSIR), Novartis (NVS), and Roche (RHHBY). While these competitors have established market presence, Longeveron's differentiators offer a compelling advantage.

Potential Challenges and Opportunities:

Challenges:

Longeveron faces several challenges, including:

  • Regulatory hurdles in gaining product approvals.
  • Competition from established players in the cell therapy market.
  • The potential for clinical trial failures.
  • Uncertainty around reimbursement for its therapies.

Opportunities:

Despite the challenges, Longeveron also has significant opportunities:

  • Large and growing addressable markets for its products.
  • Potential for breakthrough therapies with its allogeneic MSC platform.
  • Strategic partnerships with pharmaceutical companies to accelerate development and commercialization.

Recent Acquisitions:

Longeveron has not made any acquisitions in the past three years.

AI-Based Fundamental Rating:

Based on the analysis presented above, Longeveron receives an AI-based fundamental rating of 7 out of 10. This rating considers the company's strong intellectual property portfolio, promising clinical pipeline, large addressable markets, and experienced management team. However, the company's developmental stage, lack of profitability, and competitive landscape present some uncertainties.

Sources and Disclaimers:

This overview is based on information from the following sources:

  • Longeveron LLC Investor Relations website
  • Securities and Exchange Commission (SEC) filings
  • Industry reports and market research
  • News articles and media coverage

The information provided in this overview should not be considered investment advice. It is crucial to conduct your research and due diligence before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Longeveron LLC

Exchange NASDAQ Headquaters Miami, FL, United States
IPO Launch date 2021-02-12 CEO & Director Mr. Mohamed Wa'el Ahmed Hashad M.B.A.
Sector Healthcare Website https://longeveron.com
Industry Biotechnology Full time employees 23
Headquaters Miami, FL, United States
CEO & Director Mr. Mohamed Wa'el Ahmed Hashad M.B.A.
Website https://longeveron.com
Website https://longeveron.com
Full time employees 23

Longeveron Inc., a clinical stage biotechnology company, develops cellular therapies for aging-related and life-threatening conditions in the United States and Japan. The company's lead investigational product is the LOMECEL-B, an allogeneic mesenchymal stem cell formulation sourced from the bone marrow of young and healthy adult donors. It is conducting Phase 1, Phase 1/2, Phase 2a, and Phase 2b clinical trials in various indications, such as aging-related frailty, alzheimer's disease, and hypoplastic left heart syndrome. Longeveron Inc. was incorporated in 2014 and is headquartered in Miami, Florida.

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