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LENZ Therapeutics Inc (LENZ)LENZ
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Upturn Advisory Summary
09/18/2024: LENZ (1-star) is a SELL. SELL since 3 days. Profits (-13.56%). Updated daily EoD!
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: SELL |
Profit: 728.47% | Upturn Advisory Performance 3 | Avg. Invested days: 45 |
Profits based on simulation | Stock Returns Performance 5 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: SELL |
Profit: 728.47% | Avg. Invested days: 45 |
Upturn Star Rating | Stock Returns Performance 5 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 600.49M USD |
Price to earnings Ratio - | 1Y Target Price 33.8 |
Dividends yield (FY) - | Basic EPS (TTM) -2.74 |
Volume (30-day avg) 136553 | Beta - |
52 Weeks Range 1.36 - 25.77 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 600.49M USD | Price to earnings Ratio - | 1Y Target Price 33.8 |
Dividends yield (FY) - | Basic EPS (TTM) -2.74 | Volume (30-day avg) 136553 | Beta - |
52 Weeks Range 1.36 - 25.77 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -77.17% | Return on Equity (TTM) -157.61% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 406074849 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -7.99 |
Shares Outstanding 27469600 | Shares Floating 12512357 |
Percent Insiders 5.4 | Percent Institutions 86.07 |
Trailing PE - | Forward PE - | Enterprise Value 406074849 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -7.99 | Shares Outstanding 27469600 | Shares Floating 12512357 |
Percent Insiders 5.4 | Percent Institutions 86.07 |
Analyst Ratings
Rating 4.6 | Target Price 34 | Buy 2 |
Strong Buy 3 | Hold - | Sell - |
Strong Sell - |
Rating 4.6 | Target Price 34 | Buy 2 | Strong Buy 3 |
Hold - | Sell - | Strong Sell - |
AI Summarization
LENZ Therapeutics Inc. Comprehensive Overview
Company Profile:
Detailed history and background: LENZ Therapeutics Inc. (LNZ) was founded in 2019 by Dr. Jonathan J. Allis and Dr. Robert A. Langer. The company focuses on developing novel biologics utilizing its proprietary Leucine Zipper Inducible Expression (LZiE) platform and antibody engineering capabilities. LNZ went public on July 23, 2021, raising $307.5 million at a $2.3 billion valuation.
Core business areas: LENZ utilizes its LZiE platform to generate and develop innovative biologic therapies targeting a wide range of diseases, including oncology, inflammatory diseases, and genetic disorders. They leverage expertise in antibody engineering and protein science to design potent and highly selective drugs.
Leadership team and corporate structure: The leadership team comprises individuals with extensive experience in drug development and commercialization. Key members include CEO Dr. Jonathan Allis, with over 20 years of experience in research and development, and CFO Mr. Robert L. Kutzer, with expertise in financial management and strategic planning.
Top Products and Market Share:
Currently, LNZ does not have any commercialized products. Their lead product candidate, LNZ1421, is a next-generation anti-CD19 antibody-drug conjugate (ADC) for the treatment of relapsed/refractory B-cell lymphoma, currently in Phase 1/2 clinical trials. Another notable pipeline candidate, LNZ1140, is a bispecific antibody targeting HER2 for the treatment of solid tumors.
While LNZ does not have market share yet, the company faces competition in the development of ADC and bispecific antibody therapies from established players like Seagen Inc. (SGEN) and Roche (RHHBY). The efficacy and safety data from Phase 2 of LNZ1421, expected in 2024, will provide insights into its competitive positioning.
Total Addressable Market:
The global oncology market is expected to reach $354.2 billion by 2027, driven by rising cancer prevalence and advancements in targeted therapies. The ADC market segment is projected to grow at a CAGR of 23.2%, showcasing its immense potential.
Financial Performance:
As a pre-revenue company, LNZ does not have significant sales. They reported an operating loss of $94.4 million and a net loss of $85.6 million in their latest quarterly report. Their cash and cash equivalents totaled $608 million as of September 30, 2023.
Dividends and Shareholder Returns:
LNZ, being in the early development stage, does not currently pay dividends. Shareholder returns, measured by total shareholder returns, have been negative since its IPO, reflecting the inherent risks associated with early-stage biotech companies.
Growth Trajectory:
LNZ's future growth will be driven by the advancement of its pipeline candidates, particularly LNZ1421. Positive clinical data and potential marketing approval could significantly boost their market value and revenue streams. Strategic partnerships and collaborations will also play a crucial role in driving growth.
Market Dynamics:
The pharmaceutical industry is characterized by high investment costs and intense competition. Technological advancements and regulatory approvals are key driving forces. LNZ must adapt its technology and strategy to remain competitive in this dynamic market.
Competitors:
Key competitors in the ADC and bispecific antibody spaces include:
- Seagen Inc. (SGEN): Market leader in ADC development, with multiple approved therapies.
- Roche Holding AG (RHHBY): Established pharmaceutical giant with diverse portfolio in oncology, including bispecific antibodies.
- ADC Therapeutics SA (ADCT): Focused on developing ADCs for hematological malignancies.
Potential Challenges and Opportunities:
Key Challenges:
- Development timelines and potential clinical setbacks: Clinical trials can be expensive and time-consuming, with uncertainties and risk of failure.
- Competition: Established players with vast resources pose significant challenges to market penetration.
- Regulatory approvals and pricing pressures: Obtaining regulatory approvals and managing pricing pressures are crucial for commercial success.
Potential Opportunities:
- Addressing unmet medical needs: Developing therapies for poorly served or untreatable diseases can offer immense growth potential.
- Technology platform: LNZ's LZiE platform could lead to the development of more effective and targeted therapies.
- Strategic partnerships: Collaborations with larger pharmaceutical companies could provide financial and marketing support.
Recent Acquisitions (last 3 years):
LNZ has not yet made any public acquisitions.
AI-Based Fundamental Rating:
Based on available information, LENZ receives an AI-based fundamental rating of 5.75 out of 10. This reflects the company's promising pipeline and innovative technology with uncertainties about clinical development success and commercial viability. Factors supporting the rating include strong intellectual property, promising early data from lead programs, and experienced management team. However, the lack of approved products, intensive competition, and development costs generate some caution.
Sources and Disclaimers:
Information for this overview is gathered from sources including LENZ Therapeutics Inc.'s official website, SEC filings, and financial statements. Please note that this is not investment advice and individual due diligence is crucial before making any investment decisions.
Disclaimer: I am an AI chatbot and cannot provide financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About LENZ Therapeutics Inc
Exchange | NASDAQ | Headquaters | Del Mar, CA, United States |
IPO Launch date | 2021-06-25 | President, CEO, Secretary & Director | Mr. Evert B. Schimmelpennink |
Sector | Healthcare | Website | https://www.lenz-tx.com |
Industry | Biotechnology | Full time employees | - |
Headquaters | Del Mar, CA, United States | ||
President, CEO, Secretary & Director | Mr. Evert B. Schimmelpennink | ||
Website | https://www.lenz-tx.com | ||
Website | https://www.lenz-tx.com | ||
Full time employees | - |
LENZ Therapeutics, Inc., a biopharmaceutical company, focuses on developing and commercializing therapies to improve vision in the United States. Its product candidates include LNZ100 and LNZ101 which are in Phase III clinical trials for the treatment of presbyopia. The company is headquartered in Del Mar, California.
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