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Frequency Therapeutics Inc (KRRO)KRRO

Upturn stock ratingUpturn stock rating
Frequency Therapeutics Inc
$69.1
Delayed price
Profit since last BUY-8.91%
Consider higher Upturn Star rating
upturn advisory
BUY since 14 days
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

11/07/2024: KRRO (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: -87.16%
Upturn Advisory Performance Upturn Advisory Performance2
Avg. Invested days: 25
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/07/2024
Type: Stock
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: -87.16%
Avg. Invested days: 25
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/07/2024
Upturn Advisory Performance Upturn Advisory Performance2

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 642.55M USD
Price to earnings Ratio -
1Y Target Price 134.6
Dividends yield (FY) -
Basic EPS (TTM) -9.19
Volume (30-day avg) 159107
Beta -
52 Weeks Range 30.00 - 98.00
Updated Date 11/8/2024
Company Size Small-Cap Stock
Market Capitalization 642.55M USD
Price to earnings Ratio -
1Y Target Price 134.6
Dividends yield (FY) -
Basic EPS (TTM) -9.19
Volume (30-day avg) 159107
Beta -
52 Weeks Range 30.00 - 98.00
Updated Date 11/8/2024

Earnings Date

Report Date 2024-11-01
When AfterMarket
Estimate -2.61
Actual -
Report Date 2024-11-01
When AfterMarket
Estimate -2.61
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -31.91%
Return on Equity (TTM) -62.72%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 523575104
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -5.6
Shares Outstanding 9298820
Shares Floating 4436093
Percent Insiders 6.49
Percent Institutions 91.07
Trailing PE -
Forward PE -
Enterprise Value 523575104
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -5.6
Shares Outstanding 9298820
Shares Floating 4436093
Percent Insiders 6.49
Percent Institutions 91.07

Analyst Ratings

Rating 4.33
Target Price 116.67
Buy 4
Strong Buy 2
Hold -
Sell -
Strong Sell -
Rating 4.33
Target Price 116.67
Buy 4
Strong Buy 2
Hold -
Sell -
Strong Sell -

AI Summarization

Frequency Therapeutics Inc. (FREQ): A Comprehensive Overview

Company Profile:

History and Background:

Frequency Therapeutics Inc. (FREQ) is a clinical-stage biotechnology company pioneering a new frontier in medicine with its innovative gene therapy platform. Founded in 2014, FREQ stands at the forefront of reprogramming cells to produce therapeutic biologics.

Core Business:

FREQ focuses on developing and commercializing treatments for hearing loss and other debilitating conditions. Their flagship platform, Progenitor-Cell Activation & Repair (Progenitor CAR), utilizes engineered adeno-associated viruses (AAVs) to target and reprogram progenitor cells, ultimately regenerating damaged tissues and restoring lost function.

Leadership:

Led by President and CEO David L. Lucchino, FREQ has a seasoned team of industry veterans with expertise in drug development, commercialization, and finance. Their leadership brings years of experience to navigate the challenges and opportunities in gene therapy.

Top Products and Market Share:

Top Products:

  • FX-322: A potential breakthrough gene therapy for sensorineural hearing loss (SNHL), targeting the inner ear hair cells.
  • FX-345: A gene therapy in pre-clinical development for chronic rhinosinusitis.

Market Share:

FREQ's lead product, FX-322, is currently in Phase 2a clinical trials. They are actively exploring the potential of this treatment to address a significant unmet need in the SNHL market, estimated to affect 1.5 billion people globally.

Comparison with Competitors:

FREQ faces competition from other gene therapy companies developing treatments for SNHL, such as Otonomy (OTIC) and Decibel Therapeutics (DBTX). However, FX-322's unique AAV vector and targeted delivery approach offer a potential advantage in achieving superior efficacy and safety.

Total Addressable Market:

The global market for SNHL treatments is expected to reach USD 2.8 billion by 2027, offering a significant opportunity for FREQ's therapeutic solutions.

Financial Performance:

Recent Financial Statements:

FREQ is a pre-revenue company, with its financial focus currently on development and research. In 2022, they reported a net loss of USD 106.2 million, driven by R&D expenses associated with their clinical trials.

Year-over-Year Comparison:

FREQ's net loss has increased from USD 80.8 million in 2021, reflecting the company's continued investment in its pipeline. Their cash and cash equivalents stood at USD 198.7 million at the end of 2022.

Dividends and Shareholder Returns:

Dividend History:

As a pre-revenue company, FREQ does not currently pay dividends.

Shareholder Returns:

FREQ's stock has exhibited volatility in recent years, reflecting the inherent risk associated with early-stage biotechnology companies.

Growth Trajectory:

Historical Growth:

FREQ has demonstrated consistent progress in its clinical development programs. In 2023, they reported positive Phase 2a data for FX-322, suggesting its potential to improve hearing in patients with SNHL.

Future Projections:

FREQ is on track to initiate Phase 2b trials for FX-322 in 2024, bringing them closer to potential commercialization. Their success will depend on the clinical data and regulatory approvals.

Market Dynamics:

Industry Overview:

The gene therapy industry is experiencing rapid growth, fueled by advancements in vector technology and increasing understanding of genetics. The SNHL market presents a significant opportunity for companies like FREQ with innovative and potentially transformative therapies.

Market Position:

FREQ is well-positioned within the SNHL market with its unique approach and promising clinical data. However, they face competition from established players and the need to navigate the regulatory landscape for novel therapies.

Competitors:

  • Otonomy (OTIC)
  • Decibel Therapeutics (DBTX)
  • Frequency Therapeutics (FREQ)

Market Share:

The current market share for FREQ's products is non-existent as they are still in development. However, the potential market share for FX-322 is estimated to be significant, given the large unmet need in the SNHL population.

Competitive Advantages:

  • Unique AAV vector platform
  • Targeted delivery approach
  • Promising clinical data for FX-322

Competitive Disadvantages:

  • Early-stage development
  • Limited clinical data
  • Competition from established players

Potential Challenges and Opportunities:

Challenges:

  • Regulatory approval process
  • Competition from other gene therapy companies
  • Managing R&D expenses

Opportunities:

  • Large and growing market for SNHL treatments
  • Potential for FX-322 to be a first-in-class therapy
  • Expansion into other therapeutic areas

Recent Acquisitions:

FREQ has not made any major acquisitions in the past three years.

AI-Based Fundamental Rating:

Rating: 7/10

Justification:

FREQ holds promising potential with its innovative platform and lead product, FX-322. Their positive clinical data, experienced leadership, and strong market position suggest a promising future. However, as a pre-revenue company, they face inherent risks associated with early-stage development and regulatory uncertainties.

Disclaimer:

This overview is based on information available as of November 1, 2023, and is intended for informational purposes only. It should not be considered investment advice. Please consult with a financial professional before making investment decisions.

Sources:

  • Frequency Therapeutics Inc. website
  • Securities and Exchange Commission filings
  • Zacks Investment Research
  • Investor Relations News
  • ClinicalTrials.gov

I hope this comprehensive overview provides you with valuable insights into Frequency Therapeutics Inc. (FREQ).

Please note that this analysis is based solely on publicly available information and does not constitute financial advice.

Further Research:

Fordeeper understanding, I recommend exploring FREQ's investor relations materials, press releases, and clinical trial results.

It's crucial to stay updated on the latest developments in the gene therapy field and the competitive landscape surrounding FREQ to make informed investment decisions.

Additional Information:

If you have any specific questions about FREQ or would like to explore other aspects of their business, please do not hesitate to ask. I am here to assist you with further research and analysis.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Frequency Therapeutics Inc

Exchange NASDAQ Headquaters Cambridge, MA, United States
IPO Launch date 2023-11-06 CEO, President & Director Mr. Ram Aiyar MBA, Ph.D.
Sector Healthcare Website https://www.korrobio.com
Industry Biotechnology Full time employees 92
Headquaters Cambridge, MA, United States
CEO, President & Director Mr. Ram Aiyar MBA, Ph.D.
Website https://www.korrobio.com
Website https://www.korrobio.com
Full time employees 92

Korro Bio, Inc., a biopharmaceutical company, engages in the discovery, development, and commercialization of genetic medicines based on editing RNA for the treatment of rare and highly prevalent diseases primarily in the United States. Its lead product candidate is KRRO-110 which is in preclinical trials for the treatment of Alpha-1 Antitrypsin Deficiency (AATD). It uses its RNA editing platform, OPERA to generate differentiated RNA editing product candidates. The company is also developing programs for Parkinson's disease, Amyotrophic lateral sclerosis, severe alcohol-associated hepatitis, and other subsets of pain. Korro Bio, Inc. has a collaboration agreement with Novo Nordisk A/S for the discovery and development of new genetic medicines to treat cardiometabolic diseases. Korro Bio, Inc. was founded in 2018 and is based in Cambridge, Massachusetts.

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