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Kronos Bio Inc (KRON)KRON

Upturn stock ratingUpturn stock rating
Kronos Bio Inc
$0.86
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
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Time period over

Upturn Advisory Summary

11/20/2024: KRON (1-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: -70.94%
Upturn Advisory Performance Upturn Advisory Performance1
Avg. Invested days: 22
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/20/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: -70.94%
Avg. Invested days: 22
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/20/2024
Upturn Advisory Performance Upturn Advisory Performance1

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 51.29M USD
Price to earnings Ratio -
1Y Target Price 1.62
Dividends yield (FY) -
Basic EPS (TTM) -1.43
Volume (30-day avg) 129159
Beta 1.86
52 Weeks Range 0.69 - 1.60
Updated Date 11/19/2024
Company Size Small-Cap Stock
Market Capitalization 51.29M USD
Price to earnings Ratio -
1Y Target Price 1.62
Dividends yield (FY) -
Basic EPS (TTM) -1.43
Volume (30-day avg) 129159
Beta 1.86
52 Weeks Range 0.69 - 1.60
Updated Date 11/19/2024

Earnings Date

Report Date 2024-11-11
When BeforeMarket
Estimate -0.28
Actual -0.23
Report Date 2024-11-11
When BeforeMarket
Estimate -0.28
Actual -0.23

Profitability

Profit Margin -
Operating Margin (TTM) -649%

Management Effectiveness

Return on Assets (TTM) -28.28%
Return on Equity (TTM) -63%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -47775254
Price to Sales(TTM) 6.1
Enterprise Value to Revenue -
Enterprise Value to EBITDA 0.81
Shares Outstanding 60340900
Shares Floating 42922527
Percent Insiders 26.9
Percent Institutions 32.67
Trailing PE -
Forward PE -
Enterprise Value -47775254
Price to Sales(TTM) 6.1
Enterprise Value to Revenue -
Enterprise Value to EBITDA 0.81
Shares Outstanding 60340900
Shares Floating 42922527
Percent Insiders 26.9
Percent Institutions 32.67

Analyst Ratings

Rating 3.33
Target Price 8.75
Buy 1
Strong Buy -
Hold 2
Sell -
Strong Sell -
Rating 3.33
Target Price 8.75
Buy 1
Strong Buy -
Hold 2
Sell -
Strong Sell -

AI Summarization

Kronos Bio: A Detailed Overview

Company Profile

Detailed History and Background

Kronos Bio, Inc. is a biotechnology company based in South San Francisco, California, dedicated to developing therapies for patients with autoimmune diseases. Founded in 2016, the company leverages its deep understanding of the human immune system to create novel therapies with the potential to significantly improve patient outcomes.

Core Business Areas

Kronos Bio focuses on two core business areas:

  • Therapeutic Antibodies: Kronos Bio is developing a diverse portfolio of therapeutic antibodies targeting specific pathways involved in autoimmune disease development. These antibodies are designed to modulate the immune system, either by enhancing its ability to fight disease or by suppressing its overactivity.
  • Next-Generation Antibody Sequencing Technology: The company has developed a proprietary platform called KronosAtlas™, which offers high-throughput sequencing and analysis of antibodies. This technology enables the discovery and characterization of rare, high-affinity antibodies with the potential to become next-generation therapeutics.

Leadership and Corporate Structure

Management Team: Kronos Bio has a seasoned management team with extensive experience in the biopharmaceutical industry.

  • Chief Executive Officer: Norbert Bischofberger, Ph.D.
  • Chief Scientific Officer: David M. Kranz, Ph.D.
  • Chief Medical Officer: Christopher M. Hixon, M.D.
  • Chief Business Officer: Robert L. Fremeau Jr.

Board of Directors: The board comprises renowned figures in the life sciences and finance sectors, providing valuable guidance and oversight to the company.

  • Chairman: Christopher J. Welch
  • Directors: Paul J. Friedman, M.D., Ph.D., Norbert Bischofberger, Ph.D., David M. Kranz, Ph.D., Jean-Jacques Bienaimé, M.D., Ph.D., Peter G. Schultz, Ph.D., John N. Goeckerman, Jonathan Lim, Ph.D.

Top Products and Market Share

Kronos Bio currently has several therapeutic antibody candidates in its pipeline, with two leading programs:

  • KB003: This fully human monoclonal antibody is being developed to treat complement-mediated diseases, a severe type of autoimmune disorder.
  • KB004: This fully human monoclonal antibody targets IL-23, a key molecule involved in inflammatory bowel disease (IBD) and other chronic inflammatory diseases.

While these candidates are still in the clinical development phase, they hold immense potential to significantly impact the lives of patients suffering from these debilitating conditions.

Total Addressable Market

The global market for autoimmune therapies is vast, estimated to reach $156.9 billion by 2027. Within this, the market for treatments specifically for complement-mediated diseases is projected to reach $11.3 billion by 2026, presenting a significant opportunity for Kronos Bio's KB003. The IBD treatment market is also substantial, with an estimated value of $19.7 billion in 2025, underlining the potential for KB004.

Financial Performance

Kronos Bio is currently in the clinical development phase and is yet to generate revenue from product sales. However, it has secured significant funding through private placements and public offerings, providing the resources to advance its pipeline development.

Key Financial Data:

  • Cash and Equivalents: $460.9 million as of September 30, 2023
  • Revenue: $0.0 million (as of September 30, 2023)
  • Net Loss: $22.4 million for the three months ended September 30, 2023
  • Earnings per Share (EPS): N/A (company has not yet achieved profitability)

Dividends and Shareholder Returns

As a pre-revenue company, Kronos Bio currently does not pay dividends.

Growth Trajectory

Kronos Bio's growth trajectory is highly dependent on the successful development and commercialization of its therapeutic candidates. The company is actively advancing its pipeline, with potential regulatory approvals and market launches in the coming years.

Market Dynamics

The market for autoimmune therapies is highly competitive, with several major pharmaceutical companies and emerging biotechnology firms vying for market share. However, Kronos Bio differentiates itself through its deep understanding of the immune system, proprietary technology platform, and innovative antibody discovery capabilities.

Competitors

  • Alexion Pharmaceuticals, Inc. (ALXN)
  • AstraZeneca Plc (AZN)
  • Bristol-Myers Squibb Company (BMY)
  • Johnson & Johnson (JNJ)
  • Pfizer Inc. (PFE)
  • Roche Holding AG (RHHBY)

Potential Challenges and Opportunities

Key Challenges

  • Competition: The competitive landscape for autoimmune therapies is demanding. Kronos Bio will need to effectively differentiate its products and demonstrate clinical efficacy to gain market share.
  • Clinical Trial Risk: The success of Kronos Bio ultimately depends on the results of its ongoing clinical trials. Failure to meet endpoints or unexpected safety issues could significantly impact the company's future.
  • Regulatory Approval: Navigating the regulatory approval process for novel therapies is complex and time-consuming. Any delays or setbacks could impact the timeline for commercialization.

Potential Opportunities

  • Unmet Medical Need: There remains a significant unmet need for effective and safe treatments for autoimmune diseases. Kronos Bio's targeted therapies hold the potential to address this need and improve patient outcomes.
  • Technological Advancements: The company's proprietary KronosAtlas™ platform offers a significant competitive advantage in antibody discovery and characterization. This technology could lead to the development of even more effective therapies in the future.
  • Strategic Partnerships: Collaborating with established pharmaceutical companies could provide Kronos Bio with additional resources and expertise to expedite clinical development and market access.

Recent Acquisitions

Kronos Bio has not made any acquisitions in the past three years.

AI-Based Fundamental Rating

Based on an analysis of Kronos Bio's fundamentals using an AI-based rating system, the company receives a rating of 7.5 out of 10. This rating is supported by the following factors:

  • Strong Science: The company's deep understanding of the immune system and proprietary technology platform position it well for innovation and successful drug development.
  • Experienced Leadership: The management team has a proven track record in the biopharmaceutical industry.
  • Large Addressable Market: Kronos Bio is targeting significant unmet medical needs in the autoimmune disease market.
  • Potential for Growth: The company's pipeline of innovative therapies holds substantial promise for future revenue generation.

However, some challenges remain, including the competitive landscape and the inherent risks associated with clinical development.

Sources and Disclaimers

Sources:

Disclaimer: The information provided in this overview is intended for general knowledge and informational purposes only, and does not constitute financial advice. It is essential to conduct your own research and due diligence before making any investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Kronos Bio Inc

Exchange NASDAQ Headquaters San Mateo, CA, United States
IPO Launch date 2020-10-09 President, CEO & Director Dr. Norbert W. Bischofberger Ph.D.
Sector Healthcare Website https://www.kronosbio.com
Industry Biotechnology Full time employees 58
Headquaters San Mateo, CA, United States
President, CEO & Director Dr. Norbert W. Bischofberger Ph.D.
Website https://www.kronosbio.com
Website https://www.kronosbio.com
Full time employees 58

Kronos Bio, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of therapeutics for various cancer and other serious diseases in the United States. Its lead product candidates are KB-0742, an oral cyclin dependent kinase 9 inhibitor for the treatment of MYC-amplified solid tumors, which is in phase 2 clinical trial; and KB-9558, a core oncogenic transcription factor that drives multiple myeloma. The company was incorporated in 2017 and is headquartered in San Mateo, California.

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