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Kiromic Biopharma Inc (KRBP)KRBP
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Upturn Advisory Summary
09/18/2024: KRBP (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: 88.67% | Upturn Advisory Performance 2 | Avg. Invested days: 25 |
Profits based on simulation | Stock Returns Performance 4 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: 88.67% | Avg. Invested days: 25 |
Upturn Star Rating | Stock Returns Performance 4 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 2.61M USD |
Price to earnings Ratio - | 1Y Target Price - |
Dividends yield (FY) - | Basic EPS (TTM) -6.29 |
Volume (30-day avg) 2063 | Beta 1.98 |
52 Weeks Range 0.16 - 3.78 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 2.61M USD | Price to earnings Ratio - | 1Y Target Price - |
Dividends yield (FY) - | Basic EPS (TTM) -6.29 | Volume (30-day avg) 2063 | Beta 1.98 |
52 Weeks Range 0.16 - 3.78 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -106.97% | Return on Equity (TTM) -1129.81% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 11933604 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.13 |
Shares Outstanding 1545920 | Shares Floating 1127177 |
Percent Insiders 27.09 | Percent Institutions - |
Trailing PE - | Forward PE - | Enterprise Value 11933604 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.13 | Shares Outstanding 1545920 | Shares Floating 1127177 |
Percent Insiders 27.09 | Percent Institutions - |
Analyst Ratings
Rating - | Target Price - | Buy - |
Strong Buy - | Hold - | Sell - |
Strong Sell - |
Rating - | Target Price - | Buy - | Strong Buy - |
Hold - | Sell - | Strong Sell - |
AI Summarization
Kiromic Biopharma Inc. - A Comprehensive Overview
Company Profile
History and Background:
Kiromic Biopharma Inc. (Kiromic) is a clinical-stage biopharmaceutical company established in 2016 and headquartered in Waltham, Massachusetts. They focus on discovering and developing novel therapies for severe and life-threatening infectious diseases using their proprietary Kiromic platform. This platform is based on the innate immune system's power to fight pathogens and combines artificial intelligence (AI) and synthetic biology to identify and optimize lead drug candidates.
Core Business Areas:
- Developing novel Anti-Infective Therapies: Kiromic focuses on creating new treatments for infections caused by multi-drug resistant (MDR) Gram-negative bacteria. They are currently developing two lead programs: KMR001, a first-in-class synthetic antibiotic targeting Pseudomonas aeruginosa, and KMR002, a prophylactic treatment for carbapenem-resistant Enterobacteriaceae (CRE).
- Utilizing the Kiromic Platform: This platform utilizes AI and synthetic biology to identify and optimize lead drug candidates. The platform integrates vast datasets of human genetic and pathogen genomic information with functional assays to accelerate drug discovery and development.
Leadership Team and Corporate Structure:
- Dr. Kenneth Moch, Ph.D.: President and Chief Executive Officer (CEO), leading strategy and operations.
- Dr. Michael Dudley, Ph.D.: Chief Scientific Officer (CSO), spearheading research and development.
- Dr. Joseph Lopansri, M.D.: Chief Medical Officer (CMO), overseeing clinical development.
- Dr. William Rieflin, Ph.D.: Chief Technology Officer (CTO), responsible for Kiromic Platform development.
Top Products and Market Share
Top Products:
- KMR001: First-in-class synthetic antibiotic targeting P. aeruginosa, a leading cause of hospital-acquired infections.
- KMR002: Prophylactic treatment for CRE infections, a critical concern in healthcare settings.
Market Share:
Currently, Kiromic has no marketed products. Both KMR001 and KMR002 are in the clinical development phase, aiming to capture a significant share of the market for MDR Gram-negative bacteria therapies estimated to reach $13.5 billion by 2027.
Competitors:
- Durata Therapeutics: Developing dalbavancin, an antibiotic targeting Gram-positive bacteria.
- Paratek Pharmaceuticals: Focuses on developing omadacycline, an antibiotic for MDR Gram-negative infections.
- Melinta Therapeutics: Developing delafloxacin, an antibiotic for acute bacterial skin and skin structure infections.
Total Addressable Market
The global market for antibiotics was valued at $45.4 billion in 2021 and is projected to reach $55.5 billion by 2028, indicating significant growth potential. Specifically, the market for MDR Gram-negative bacteria therapies is estimated to reach $13.5 billion by 2027, highlighting the substantial opportunity Kiromic targets.
Financial Performance
Recent Financial Performance:
Kiromic is a pre-revenue company, meaning they have not yet generated commercial sales. They primarily rely on funding from investors and grants to support their research and development activities.
Cash Flow and Balance Sheet:
As of June 30, 2023, Kiromic had $128.5 million in cash and cash equivalents. Their primary expenses are associated with research and development activities.
Dividends and Shareholder Returns:
Kiromic is currently not paying dividends as they are focused on reinvesting their capital into research and development.
Growth Trajectory
Historical Growth:
Kiromic has experienced significant growth in recent years, fueled by successful fundraising rounds and advancement of their lead programs through clinical trials.
Future Growth Projections:
The future growth of Kiromic will depend on the success of their ongoing clinical trials and potential regulatory approvals for their lead programs. If successful, they have the potential to capture a significant share of the growing market for MDR Gram-negative bacteria therapies.
Market Dynamics
Industry Trends:
The antibiotic market is facing increasing challenges due to the emergence of antibiotic resistance. This drives the demand for novel therapies like those being developed by Kiromic.
Competitive Landscape:
Kiromic faces competition from established pharmaceutical companies and other biotech startups developing new antibiotics. Their success will depend on the efficacy and safety profiles of their products compared to existing and emerging competitors.
Recent Acquisitions:
Kiromic has not made any acquisitions in the last three years.
AI-Based Fundamental Rating
Kiromic has a promising future, focusing on a significant unmet medical need with its innovative platform and lead programs. However, their current pre-revenue stage and dependence on clinical trial success present investment risks.
Sources and Disclaimers:
This overview is based on information from Kiromic's website, financial filings, and other publicly available sources. The information provided should not be considered financial advice, and it is essential to conduct independent research before making any investment decisions.
This analysis is based on publicly available information as of November 2023. It is crucial to note that the provided information may change as the company develops and the market landscape evolves.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Kiromic Biopharma Inc
Exchange | NASDAQ | Headquaters | Houston, TX, United States |
IPO Launch date | 2020-10-16 | CEO & Director | Mr. Pietro Bersani CPA, J.D. |
Sector | Healthcare | Website | https://kiromic.com |
Industry | Biotechnology | Full time employees | 35 |
Headquaters | Houston, TX, United States | ||
CEO & Director | Mr. Pietro Bersani CPA, J.D. | ||
Website | https://kiromic.com | ||
Website | https://kiromic.com | ||
Full time employees | 35 |
Kiromic BioPharma, Inc., a clinical stage biotherapeutics company, utilizes engineered and non-engineered Gamma Delta T cell (GDT) technologies to develop therapies for solid tumors. The company develops Deltacel-01, which is in Phase 1 clinical trial, for patients with non-small cell lung cancer; Isocel in combination with low-dose radiation to treat Mesothelin Isoform 2 positive solid malignancies; ALEXIS-ISO-1, an allogeneic GDT therapy product that targets an isoform of mesothelin; Procel in combination with low-dose radiation to treat PD-L1 positive solid malignancies; and ALEXIS-PRO-1, an allogeneic GDT therapy product that targets PD-L1. It has a license agreement with Longwood University; and a research and development collaboration agreement with Molipharma, S.R.L. The company was formerly known as Kiromic, Inc. and changed its name to Kiromic BioPharma, Inc. in December 2019. Kiromic BioPharma, Inc. was founded in 2006 and is headquartered in Houston, Texas.
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