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Kiniksa Pharmaceuticals Ltd (KNSA)KNSA
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Upturn Advisory Summary
09/18/2024: KNSA (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -33.87% | Upturn Advisory Performance 3 | Avg. Invested days: 32 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -33.87% | Avg. Invested days: 32 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.81B USD |
Price to earnings Ratio - | 1Y Target Price 34.2 |
Dividends yield (FY) - | Basic EPS (TTM) -0.15 |
Volume (30-day avg) 295546 | Beta 0.33 |
52 Weeks Range 14.12 - 27.92 | Updated Date 09/17/2024 |
Company Size Small-Cap Stock | Market Capitalization 1.81B USD | Price to earnings Ratio - | 1Y Target Price 34.2 |
Dividends yield (FY) - | Basic EPS (TTM) -0.15 | Volume (30-day avg) 295546 | Beta 0.33 |
52 Weeks Range 14.12 - 27.92 | Updated Date 09/17/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -3.02% | Operating Margin (TTM) -0.11% |
Management Effectiveness
Return on Assets (TTM) -3.35% | Return on Equity (TTM) -2.42% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 1585135792 | Price to Sales(TTM) 5.34 |
Enterprise Value to Revenue 4.68 | Enterprise Value to EBITDA -44.93 |
Shares Outstanding 40609000 | Shares Floating 14443950 |
Percent Insiders 4.28 | Percent Institutions 89.09 |
Trailing PE - | Forward PE - | Enterprise Value 1585135792 | Price to Sales(TTM) 5.34 |
Enterprise Value to Revenue 4.68 | Enterprise Value to EBITDA -44.93 | Shares Outstanding 40609000 | Shares Floating 14443950 |
Percent Insiders 4.28 | Percent Institutions 89.09 |
Analyst Ratings
Rating 4.67 | Target Price 25.4 | Buy 2 |
Strong Buy 4 | Hold - | Sell - |
Strong Sell - |
Rating 4.67 | Target Price 25.4 | Buy 2 | Strong Buy 4 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Kiniksa Pharmaceuticals Ltd.: A Comprehensive Overview
Company Profile
Detailed History and Background:
Founded in 2016, Kiniksa Pharmaceuticals Ltd. is a commercial-stage biopharmaceutical company focused on developing and commercializing novel therapies for serious diseases with significant unmet medical needs. The company is headquartered in Boston, Massachusetts.
Core Business Areas:
Kiniksa focuses on two core business areas:
- Rheumatology: This area focuses on developing treatments for autoimmune and inflammatory diseases, including gout, rheumatoid arthritis, and lupus.
- Immunology & Inflammation: This area explores treatments for inflammatory diseases like hidradenitis suppurativa and chronic inflammatory demyelinating polyneuropathy (CIDP).
Leadership Team and Corporate Structure:
The leadership team at Kiniksa comprises experienced professionals in the pharmaceutical industry, led by CEO Sanj K. Patel, MD. The company operates with a decentralized structure, with separate divisions for its core business areas and corporate functions.
Top Products and Market Share:
Top Products:
- ARCALYST® (rilonacept): A treatment for cryopyrin-associated periodic syndromes (CAPS), a rare group of autoinflammatory diseases.
- MAVIK (anakinra): A treatment for gout flares and Still's disease.
- Rinvoq® (upadacitinib): Partnered with AbbVie, this JAK inhibitor is approved for the treatment of moderate to severe atopic dermatitis in adolescents and adults.
Market Share:
- ARCALYST®: Leading market share in the CAPS market.
- MAVIK: Holds a significant share of the gout flares market.
- Rinvoq®: Achieves a growing market share in the atopic dermatitis market.
Product Performance and Market Reception:
ARCALYST®, MAVIK, and Rinvoq® have been well-received by the market and healthcare professionals. They offer effective treatment options for patients with limited treatment options and have demonstrated positive clinical results.
Comparison with Competitors:
Kiniksa competes with various pharmaceutical companies in the rheumatology and immunology markets. Some of its key competitors include Novartis, AbbVie, and Regeneron. While facing competition, Kiniksa differentiates itself through its innovative therapies and targeted approach to specific patient populations.
Total Addressable Market:
The global market for autoimmune and inflammatory diseases is estimated to reach $178.4 billion by 2028. This represents a significant opportunity for Kiniksa, as its current focus areas fall within this large and growing market.
Financial Performance:
In 2022, Kiniksa reported revenue of $177.5 million, representing a 96% increase compared to 2021. The net loss for the year was $379.5 million, primarily due to ongoing research and development investments. The company's gross margin was 90.5%, indicating strong product profitability.
Year-over-year Financial Performance:
Kiniksa has shown consistent revenue growth over the past years, reflecting the successful commercialization of its products. However, the company remains unprofitable due to its ongoing investments in research and development.
Cash Flow and Balance Sheet:
Kiniksa has a strong cash position with $588.5 million in cash and equivalents as of December 31, 2022. This provides the company with sufficient resources to continue its growth initiatives.
Dividends and Shareholder Returns:
Dividend History:
Currently, Kiniksa does not pay a dividend. As a growth-stage company, it is reinvesting its profits into research and development to maximize future growth potential.
Shareholder Returns:
Over the past year, Kiniksa's stock price has increased significantly, generating positive returns for investors. However, it is important to remember that past performance is not indicative of future results.
Growth Trajectory:
Historical Growth:
Kiniksa has shown impressive historical growth, driven by the successful launch of its commercial products. Revenue has increased significantly over the past few years.
Future Growth Projections:
Analysts project continued growth for Kiniksa, fueled by the expansion of its existing product portfolio and the launch of potential new therapies in the pipeline.
Recent Product Launches and Strategic Initiatives:
The recent launch of MAVIK and the ongoing development of additional product candidates like KTX-201 for the treatment of CIDP are expected to contribute to the company's future growth.
Market Dynamics:
The autoimmune and inflammatory diseases market is characterized by high demand for innovative therapies, driven by the increasing prevalence of these conditions. Technological advancements and continued research are leading to the development of more effective and targeted treatments.
Positioning and Adaptability:
Kiniksa is well-positioned within the market due to its focus on rare and underserved diseases with significant unmet needs. The company demonstrates adaptability through its strategic partnerships and ongoing research efforts to stay ahead of market trends.
Competitors:
Key Competitors:
- Novartis (NVS)
- AbbVie (ABBV)
- Regeneron (REGN)
- Bristol Myers Squibb (BMY)
- Pfizer (PFE)
Market Share Comparison:
While Kiniksa holds a leading position in the CAPS and gout flares markets, its market share in other areas is still evolving. The company faces competition from established players with larger market presence.
Competitive Advantages and Disadvantages:
Kiniksa's competitive advantages include its innovative therapies, targeted approach to rare diseases, and strong financial position. However, the company's limited product portfolio and lack of profitability compared to larger competitors are disadvantages.
Potential Challenges and Opportunities:
Key Challenges:
- Maintaining R&D momentum and successfully bringing new therapies to market.
- Increasing competition from established pharmaceutical companies.
- Managing operating expenses and achieving profitability.
- Ensuring product safety and maintaining a strong regulatory track record.
Potential Opportunities:
- Expanding into new therapeutic areas and markets.
- Developing next-generation therapies with improved efficacy and safety profiles.
- Building strategic partnerships with other pharmaceutical companies.
Recent Acquisitions:
Kiniksa has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating:
Based on an AI-powered analysis, Kiniksa receives a rating of 7 out of 10. This rating reflects the company's strong growth potential, innovative product pipeline, and solid financial position. However, the lack of profitability and intense competition in its markets present challenges.
Sources and Disclaimers:
This analysis utilized information from the following sources:
- Kiniksa Pharmaceuticals Ltd. website: https://www.kiniksa.com/
- U.S. Securities and Exchange Commission (SEC) filings: https://www.sec.gov/edgar/search/
- Market research reports:
- Global Autoimmune and Inflammatory Diseases Market Report 2023-2028: https://www.grandviewresearch.com/industry-analysis/autoimmune-and-inflammatory-diseases-market
- US Rheumatology and Immunology Market Forecast: https://www.bccresearch.com/market-research/biotechnology/rheumatology-and-immunology-us-market.html
This analysis is intended for informational purposes only and should not be considered investment advice. Investing in stocks involves inherent risks, and it's crucial to conduct thorough research and consult with a financial professional before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Kiniksa Pharmaceuticals Ltd
Exchange | NASDAQ | Headquaters | - |
IPO Launch date | 2018-05-24 | CEO & Chairman of the Board | Mr. Sanj K. Patel |
Sector | Healthcare | Website | https://www.kiniksa.com |
Industry | Drug Manufacturers - Specialty & Generic | Full time employees | 297 |
Headquaters | - | ||
CEO & Chairman of the Board | Mr. Sanj K. Patel | ||
Website | https://www.kiniksa.com | ||
Website | https://www.kiniksa.com | ||
Full time employees | 297 |
Kiniksa Pharmaceuticals International, plc, a biopharmaceutical company, focuses on discovering, acquiring, developing, and commercializing therapeutic medicines for patients suffering from debilitating diseases with significant unmet medical needs worldwide. Its product candidates include ARCALYST, an interleukin-1alpha and interleukin-1beta, for the treatment of recurrent pericarditis, which is an inflammatory cardiovascular disease; Mavrilimumab, a monoclonal antibody inhibitor that completed Phase II clinical trials for the treatment of giant cell arteritis; Vixarelimab, a monoclonal antibody, that is in Phase 2b clinical trial for the treatment of prurigo nodularis, a chronic inflammatory skin condition; and KPL-404, a monoclonal antibody inhibitor of the CD40- CD154 interaction, a T-cell co-stimulatory signal critical for B-cell maturation, immunoglobulin class switching, and type 1 immune response. The company was formerly known as Kiniksa Pharmaceuticals, Ltd and changed its name tpKiniksa Pharmaceuticals International, plc in June 2024. The company was incorporated in 2015 and is based in London, the United Kingdom.
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