Cancel anytime
Janux Therapeutics Inc (JANX)JANX
- BUY Advisory
- Profitable SELL
- Loss-Inducing SELL
- Profit
- Loss
- PASS (Skip invest)*
- ALL
- YEAR
- MONTH
- WEEK
Upturn Advisory Summary
08/30/2024: JANX (3-star) is a STRONG-BUY. BUY since 1 days. Profits (0.00%). Updated daily EoD!
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Strong Buy |
Profit: 52.3% | Upturn Advisory Performance 2 | Avg. Invested days: 25 |
Profits based on simulation | Stock Returns Performance 3 | Last Close 08/30/2024 |
Type: Stock | Today’s Advisory: Strong Buy |
Profit: 52.3% | Avg. Invested days: 25 |
Upturn Star Rating | Stock Returns Performance 3 |
Profits based on simulation Last Close 08/30/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 2.58B USD |
Price to earnings Ratio - | 1Y Target Price 67.5 |
Dividends yield (FY) - | Basic EPS (TTM) -0.88 |
Volume (30-day avg) 502228 | Beta 3.57 |
52 Weeks Range 5.65 - 65.60 | Updated Date 09/18/2024 |
Company Size Mid-Cap Stock | Market Capitalization 2.58B USD | Price to earnings Ratio - | 1Y Target Price 67.5 |
Dividends yield (FY) - | Basic EPS (TTM) -0.88 | Volume (30-day avg) 502228 | Beta 3.57 |
52 Weeks Range 5.65 - 65.60 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -291.17% | Operating Margin (TTM) -155.36% |
Management Effectiveness
Return on Assets (TTM) -7.98% | Return on Equity (TTM) -9.2% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 1957583071 | Price to Sales(TTM) 170.56 |
Enterprise Value to Revenue 129.41 | Enterprise Value to EBITDA -33.8 |
Shares Outstanding 52164500 | Shares Floating 28870221 |
Percent Insiders 9.42 | Percent Institutions 99.72 |
Trailing PE - | Forward PE - | Enterprise Value 1957583071 | Price to Sales(TTM) 170.56 |
Enterprise Value to Revenue 129.41 | Enterprise Value to EBITDA -33.8 | Shares Outstanding 52164500 | Shares Floating 28870221 |
Percent Insiders 9.42 | Percent Institutions 99.72 |
Analyst Ratings
Rating 4.7 | Target Price 27.25 | Buy 1 |
Strong Buy 8 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.7 | Target Price 27.25 | Buy 1 | Strong Buy 8 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Company Profile
Detailed History and Background of Janux Therapeutics Inc.
Janux Therapeutics Inc. (NASDAQ: JANX) is a clinical-stage biopharmaceutical company founded in 2016 and headquartered in Cambridge, Massachusetts. The company focuses on discovering and developing novel small molecule therapies for people with severe autoimmune and inflammatory diseases.
Janux's lead product candidate is PTX-200, a potent and selective inhibitor of Bruton’s tyrosine kinase (BTK), which is an enzyme that plays a critical role in B cell signaling and activation. The company is currently conducting Phase 2 clinical trials for PTX-200 in patients with moderate-to-severe rheumatoid arthritis (RA) and lupus nephritis (LN).
Description of the Company’s Core Business Areas
Janux Therapeutics is primarily focused on developing innovative therapies for autoimmune and inflammatory diseases with high unmet medical needs. The company utilizes its deep understanding of immunology and drug discovery to create highly selective and potent small molecule therapies that target key pathways in the immune system.
Overview of the Company’s Leadership Team and Corporate Structure
Janux's leadership team comprises experienced individuals with extensive expertise in drug development, business strategy, and finance. The current CEO is David E. Lee, a seasoned pharmaceutical executive with over 25 years of experience in the industry.
The company operates a lean corporate structure, with a focus on efficiency and agility. Key departments include research and development, clinical development, corporate development, and finance.
Top Products and Market Share
Identification and Description of Janux Therapeutics Inc's Top Products and Offerings
Janux's top product candidate is PTX-200, a highly selective BTK inhibitor currently in Phase 2 clinical trials for RA and LN. The company also has other preclinical programs targeting various autoimmune and inflammatory diseases.
Analysis of the Market Share of These Products in the Global and US Markets
BTK inhibitors are a rapidly growing class of drugs in the treatment of autoimmune and inflammatory diseases. The global market for BTK inhibitors is expected to reach $12.5 billion by 2027. In the US, the market is estimated to be around $6 billion.
PTX-200 has the potential to capture a significant share of the BTK inhibitor market if it proves to be safe and effective in clinical trials. The company is initially focusing on the US market, but it could expand to other markets in the future.
Comparison of Product Performance and Market Reception Against Competitors
PTX-200 faces competition from other BTK inhibitors, such as ibrutinib (Imbruvica), acalabrutinib (Calquence), and zanubrutinib (Brukinsa). These drugs have demonstrated efficacy in various autoimmune and inflammatory diseases, and they have established market share.
PTX-200 has the potential to differentiate itself from its competitors by offering a more favorable safety profile and greater efficacy in specific patient populations. The company is currently conducting clinical trials to demonstrate these advantages.
Total Addressable Market
The global market for autoimmune and inflammatory diseases is estimated to be over $200 billion, and it is expected to grow significantly in the coming years. The growing prevalence of these diseases, coupled with the rising demand for novel and effective therapies, is driving market growth.
Financial Performance
Detailed Analysis of Recent Financial Statements
- Revenue: Janux has not yet generated any product revenue, as it is still in the clinical development stage.
- Net Income: The company has incurred significant net losses due to its ongoing research and development expenses. In 2022, the net loss was approximately $68.4 million.
- Profit Margins: Janux currently has negative profit margins due to its pre-commercialization stage.
- Earnings per Share (EPS): The company's EPS is also negative, reflecting the net losses.
Year-over-Year Financial Performance Comparison
Janux's financial performance has been marked by increasing research and development expenses as the company advances its clinical programs. The company has secured funding through collaborations and public offerings to support its development activities.
Examination of Cash Flow Statements and Balance Sheet Health
Janux's cash flow statement shows negative operating cash flow due to the company's ongoing research and development activities. The company has a strong balance sheet with significant cash and investments, providing it with financial flexibility.
Dividends and Shareholder Returns
Dividend History:
Janux does not currently pay dividends, as it is focused on reinvesting its resources into research and development.
Shareholder Returns:
The company's stock price has been volatile, reflecting the risks associated with clinical-stage biopharmaceutical companies. However, investors who bought shares during the initial public offering in 2020 have experienced significant gains.
Growth Trajectory
Historical Growth Analysis over the Past 5 to 10 Years
Janux is a relatively young company, and its historical growth analysis is limited. However, the company has shown significant progress in advancing its clinical programs and expanding its pipeline.
Future Growth Projections based on Industry Trends and Company Guidance
The autoimmune and inflammatory disease market is expected to offer significant growth opportunities for Janux in the coming years. The company's management team is optimistic about its prospects and has guided for continued clinical development progress and potential regulatory approvals for PTX-200 in the near future.
Recent Product Launches and Strategic Initiatives on Growth Prospects
Janux has not yet launched any products, but it is actively pursuing strategic initiatives to enhance its growth prospects. These initiatives include collaborations with research institutions, licensing agreements with other companies, and potential acquisitions.
Market Dynamics
Overview of the Industry Stock Janux Therapeutics Inc operates in, including current trends, demand-supply scenarios, and technological advancements
The autoimmune and inflammatory disease market is characterized by intense competition, rapidly evolving treatment modalities, and increasing patient demand for innovative therapies. Janux is well-positioned within this dynamic industry due to its focus on novel drug discovery and development.
Analysis of how Janux Therapeutics Inc is positioned within the industry and its adaptability to market changes
Janux's strategy of developing highly selective and potent BTK inhibitors is well-aligned with the current market trends and patient needs. The com
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Janux Therapeutics Inc
Exchange | NASDAQ | Headquaters | San Diego, CA, United States |
IPO Launch date | 2021-06-11 | President, CEO & Director | Dr. David Alan Campbell Ph.D. |
Sector | Healthcare | Website | https://www.januxrx.com |
Industry | Biotechnology | Full time employees | 69 |
Headquaters | San Diego, CA, United States | ||
President, CEO & Director | Dr. David Alan Campbell Ph.D. | ||
Website | https://www.januxrx.com | ||
Website | https://www.januxrx.com | ||
Full time employees | 69 |
Janux Therapeutics, Inc., a clinical stage biopharmaceutical company, develops immunotherapies based on Tumor Activated T Cell Engagers (TRACTr) and Tumor Activated Immunomodulators (TRACIr) platforms technology to treat patients suffering from cancer. The company's clinical candidates comprise JANX007, a prostate-specific membrane antigen or PSMA-TRACTr, which is in Phase 1 clinical trial in adults for the treatment of metastatic castration-resistant prostate cancer (mCRPC) and the vasculature of other tumors; and JANX008, an epidermal growth factor receptor or EGFR-TRACTr that is in Phase 1 clinical trial for the treatment of multiple solid cancers, including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, and renal cell carcinoma. Its development pipeline also consists of discovery stage products. The company has strategic research collaboration agreement with Merck Sharp & Dohme Corp. to develop TRACTr product candidates. Janux Therapeutics, Inc. was incorporated in 2017 and is headquartered in San Diego, California.
Note: This website is maintained by Upturn Corporation, which is an investment adviser registered with the U.S. Securities and Exchange Commission. Such registration does not imply a certain level of skill or training. Investing in securities has risks. Past performance is no guarantee of future returns. No assurance is provided as to any particular investment return, and you may lose money using our services. You are strongly advised to consult appropriate counsel before making any investments in companies you learn about through our services. You should obtain appropriate legal, tax, investment, accounting, and other advice that takes into account your investment portfolio and overall financial situation. You are solely responsible for conducting due diligence on a potential investment. We do not affect trades for you. You will select your own broker through which to transact. Investments are not FDIC insured, they are not guaranteed, and they may lose value. Please see the Privacy Policy, Terms of Use, and Disclosure for more information.