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Upturn AI SWOT - About
Opus Genetics, Inc. (IRD)
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Upturn Advisory Summary
04/07/2025: IRD (1-star) is currently NOT-A-BUY. Pass it for now.
Upturn Star Rating
Not Recommended Performance
These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.
AI Based Fundamental Rating
Below Average Performance
These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.
Analysis of Past Performance
Type Stock | Historic Profit -65.59% | Avg. Invested days 20 | Today’s Advisory PASS |
Upturn Star Rating | Upturn Advisory Performance  2.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 04/07/2025 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 35.67M USD | Price to earnings Ratio - | 1Y Target Price 10.5 |
Price to earnings Ratio - | 1Y Target Price 10.5 | ||
Volume (30-day avg) 244791 | Beta 0.24 | 52 Weeks Range 0.80 - 2.18 | Updated Date 04/4/2025 |
52 Weeks Range 0.80 - 2.18 | Updated Date 04/4/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.09 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -207.11% |
Management Effectiveness
Return on Assets (TTM) -38.95% | Return on Equity (TTM) -64.3% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -962644 | Price to Sales(TTM) 4.26 |
Enterprise Value -962644 | Price to Sales(TTM) 4.26 | ||
Enterprise Value to Revenue 0.2 | Enterprise Value to EBITDA -2.55 | Shares Outstanding 31568500 | Shares Floating 27724682 |
Shares Outstanding 31568500 | Shares Floating 27724682 | ||
Percent Insiders 16.15 | Percent Institutions 16.63 |
Analyst Ratings
Rating 4.75 | Target Price - | Buy 1 | Strong Buy 3 |
Buy 1 | Strong Buy 3 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Opus Genetics, Inc.
Company Overview
History and Background
Opus Genetics is a gene therapy company focused on developing treatments for inherited retinal diseases. Founded in 2020 as a spin-out from the University of Pennsylvania and Childrenu2019s Hospital of Philadelphia (CHOP), it aims to address unmet needs in inherited retinal disease (IRD) therapy development.
Core Business Areas
- Gene Therapy Development: Focuses on developing gene therapy candidates for specific IRDs, leveraging AAV vectors to deliver functional genes to retinal cells.
- Platform Technology: Utilizes a proprietary AAV platform optimized for retinal delivery and expression.
- Clinical Trials: Conducts clinical trials to evaluate the safety and efficacy of gene therapy candidates in patients with IRDs.
Leadership and Structure
Opus Genetics has a management team with experience in gene therapy, ophthalmology, and drug development. The company structure is based on functional departments supporting research, development, and clinical operations.
Top Products and Market Share
Key Offerings
- OPI-005 (RHO-linked autosomal dominant retinitis pigmentosa (adRP)): Gene therapy candidate for RHO-linked adRP. Market share data is unavailable as it is still in development. Competitors include companies developing gene therapies for inherited retinal diseases.
- OPI-004 (Leber congenital amaurosis (LCA)): Gene therapy candidate for LCA. Market share data is unavailable as it is still in development. Competitors include companies developing gene therapies for inherited retinal diseases.
Market Dynamics
Industry Overview
The gene therapy market for inherited retinal diseases is growing, driven by advancements in gene editing and delivery technologies and the high unmet need for effective treatments.
Positioning
Opus Genetics is positioned as a specialist in inherited retinal disease gene therapy, focusing on developing targeted therapies for specific genetic mutations.
Total Addressable Market (TAM)
The global inherited retinal disease market is estimated to be in the billions of dollars. Opus Genetics is targeting specific genetic subtypes within this broader market.
Upturn SWOT Analysis
Strengths
- Specialized focus on inherited retinal diseases
- Proprietary AAV vector platform
- Experienced management team
- Strong scientific foundation (spin-out from UPenn/CHOP)
Weaknesses
- Early-stage company with limited revenue
- High R&D expenses
- Dependence on clinical trial success
- Limited commercial infrastructure
Opportunities
- Potential to address unmet needs in IRDs
- Expanding gene therapy market
- Strategic partnerships with larger pharmaceutical companies
- Expansion of pipeline to additional IRD targets
Threats
- Clinical trial failures
- Competition from established pharmaceutical companies
- Regulatory hurdles
- Manufacturing challenges
Competitors and Market Share
Key Competitors
- SPRK
- EDIT
- CRSP
Competitive Landscape
Opus Genetics competes with both established pharmaceutical companies and smaller biotech firms in the gene therapy space. Its competitive advantage lies in its specialized focus on inherited retinal diseases and proprietary AAV platform.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth data is not publicly available.
Future Projections: Future projections are not publicly available, but the company's success hinges on clinical trial progress and regulatory approvals.
Recent Initiatives: Recent initiatives include advancing gene therapy candidates through clinical trials and expanding its research and development efforts.
Summary
Opus Genetics is a promising gene therapy company focused on inherited retinal diseases. It has a strong scientific foundation and a specialized AAV platform. However, it is an early-stage company with high R&D expenses and dependence on clinical trial success and needs to be aware of larger competitors in the market.
Similar Companies
CRSP
Crispr Therapeutics AG
CRSP
Crispr Therapeutics AG
EDIT
Editas Medicine Inc
EDIT
Editas Medicine Inc
Sources and Disclaimers
Data Sources:
- Company website
- Press releases
- Industry reports
Disclaimers:
This analysis is based on publicly available information and limited by the company's private status. Market share data is estimated and may not be precise. Investment decisions should be based on independent research and professional advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Opus Genetics, Inc.
Exchange NASDAQ | Headquaters Farmington Hills, MI, United States | ||
IPO Launch date 2005-05-23 | CEO - | ||
Sector Healthcare | Industry Biotechnology | Full time employees - | Website https://opusgtx.com |
Full time employees - | Website https://opusgtx.com | ||
Opus Genetics, Inc., a clinical-stage ophthalmic biopharmaceutical company, focuses on developing and commercializing therapies for the treatment of unmet needs of patients with refractive and retinal eye disorders. The company offers Phentolamine Ophthalmic Solution for reversal of mydriasis, as well as is in Phase III clinical trials for presbyopia and dim light or night vision disturbances. Its lead retinal product candidate is APX3330, a small-molecule inhibitor of reduction oxidation effector factor-1 protein that has completed Phase II clinical trial for the treatment of diabetic retinopathy. The company also develops APX2009 and APX2014 that are preclinical product candidates for retina indications. The company was formerly known as Ocuphire Pharma, Inc. Opus Genetics, Inc. was founded in 2018 and is headquartered in Farmington Hills, Michigan.
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