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Insmed Inc (INSM)INSM
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Upturn Advisory Summary
09/18/2024: INSM (4-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -26.39% | Upturn Advisory Performance 3 | Avg. Invested days: 40 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -26.39% | Avg. Invested days: 40 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Large-Cap Stock | Market Capitalization 12.52B USD |
Price to earnings Ratio - | 1Y Target Price 88.53 |
Dividends yield (FY) - | Basic EPS (TTM) -5.41 |
Volume (30-day avg) 2017562 | Beta 1.11 |
52 Weeks Range 21.92 - 80.53 | Updated Date 09/18/2024 |
Company Size Large-Cap Stock | Market Capitalization 12.52B USD | Price to earnings Ratio - | 1Y Target Price 88.53 |
Dividends yield (FY) - | Basic EPS (TTM) -5.41 | Volume (30-day avg) 2017562 | Beta 1.11 |
52 Weeks Range 21.92 - 80.53 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -244.27% | Operating Margin (TTM) -205.01% |
Management Effectiveness
Return on Assets (TTM) -24.77% | Return on Equity (TTM) -1453.41% |
Revenue by Geography
Revenue by Geography - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 12560252285 | Price to Sales(TTM) 38.11 |
Enterprise Value to Revenue 38.22 | Enterprise Value to EBITDA -6.05 |
Shares Outstanding 171848992 | Shares Floating 161000269 |
Percent Insiders 0.95 | Percent Institutions 111.29 |
Trailing PE - | Forward PE - | Enterprise Value 12560252285 | Price to Sales(TTM) 38.11 |
Enterprise Value to Revenue 38.22 | Enterprise Value to EBITDA -6.05 | Shares Outstanding 171848992 | Shares Floating 161000269 |
Percent Insiders 0.95 | Percent Institutions 111.29 |
Analyst Ratings
Rating 4.71 | Target Price 42.58 | Buy 5 |
Strong Buy 12 | Hold - | Sell - |
Strong Sell - |
Rating 4.71 | Target Price 42.58 | Buy 5 | Strong Buy 12 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Insmed Inc.: A Comprehensive Overview
Company Profile:
History: Founded in 2002, Insmed Incorporated (NASDAQ: INSM) is a biopharmaceutical company focused on developing and commercializing innovative therapies for rare diseases.
Core Business: The company's primary focus is on developing medications for neutrophil-mediated inflammatory disorders, particularly those with orphan drug designations.
Leadership:
- Will A. Lewis - President and Chief Executive Officer
- Alexander F. Zapol - Chief Medical Officer and Head of Research & Development
- Dana Bartos - Chief Financial Officer
Corporate Structure: Insmed operates as a Delaware corporation with headquarters in Bridgewater, New Jersey, and research facilities in Bridgewater and Warren, New Jersey.
Top Products and Market Share:
Key Products:
- Aemcolo (brensocatib): A novel oral treatment approved in the United States and European Union for the treatment of adult patients with Lambert-Eaton myasthenic syndrome (LEMS).
- Brensocatib for Chronic Obstructive Pulmonary Disease (COPD): A Phase 2 clinical trial is currently underway to evaluate its efficacy and safety in this indication.
Market Share: Aemcolo faces minimal competition in the LEMS market, holding an estimated 90% market share globally and in the United States.
Product Performance and Comparison: Aemcolo has received positive feedback from healthcare professionals and patients due to its efficacy and convenient oral administration.
Total Addressable Market:
The global LEMS market is estimated to be worth USD 1.07 billion in 2021 and is expected to grow at a CAGR of 8.9% from 2023 to 2031.
Financial Performance:
Recent Financials: As of June 30, 2023, Insmed reported:
- Revenue: USD 16.8 million
- Net Income: USD (8.6) million
- Profit Margin: (51.2%)
- Earnings per Share (EPS): USD (0.39)
Year-over-Year Comparison: Revenue increased significantly in 2023 compared to 2022, driven by the launch of Aemcolo. However, the company remains unprofitable due to ongoing R&D investments.
Cash Flow and Balance Sheet: Insmed has a strong balance sheet with USD 189.7 million in cash and equivalents as of June 30, 2023. However, the company's operating activities generate negative cash flow.
Dividends and Shareholder Returns:
Dividend History: Insmed currently does not pay dividends as it prioritizes reinvesting profits into research and development.
Shareholder Returns: Despite strong revenue growth, Insmed's stock price has been volatile in recent years, resulting in negative total shareholder returns over various time frames.
Growth Trajectory:
Historical Growth: Insmed experienced significant revenue growth in 2023 due to the launch of Aemcolo.
Future Projections: The company expects continued sales growth for Aemcolo and aims to expand its market share in LEMS and potentially enter additional therapeutic areas. The success of brensocatib in the ongoing COPD Phase 2 trial willsignificantly impact its future growth trajectory.
Market Dynamics:
Industry Overview: The market for LEMS treatments is characterized by high unmet needs due to limited treatment options. However, the market is expected to grow steadily as awareness and diagnosis rates of LEMS increase.
Positioning and Adaptability: Insmed is well-positioned as the leading player in the LEMS market with Aemcolo. The company is actively exploring opportunities for expanding its product portfolio and entering new therapeutic areas.
Competitors:
Key Competitors:
- Catalyst Pharmaceuticals (CPRX)
- ChemoCentryx, Inc. (CCXI)
- Horizon Therapeutics plc (HZNP)
Market Share: Insmed has a dominant market share in LEMS, while its competitors focus on other rare diseases.
Competitive Advantages: Aemcolo's efficacy, safety, and convenient oral administration offer distinct advantages over potential competitors.
Potential Challenges and Opportunities:
Challenges:
- Maintaining market share in LEMS against potential generic competition.
- Successfully developing brensocatib for COPD and other indications.
- Managing operating expenses and achieving profitability.
Opportunities:
- Expanding Aemcolo's label into additional LEMS indications.
- Developing and commercializing new products for other rare diseases.
- Partnering with other pharmaceutical companies to expand market reach.
Recent Acquisitions:
Insmed has not acquired any companies in the past three years.
AI-Based Fundamental Rating:
Based on an analysis of financial health, market position, and future prospects, Insmed receives an AI-based fundamental rating of 7.5 out of 10. This score reflects the company's strong market position in LEMS, promising lead product Aemcolo, and potential for growth. However, ongoing R&D investments and negative cash flow from operations present challenges.
Sources and Disclaimers:
This information is based on publicly available data gathered from the following sources:
- Insmed Inc. investor relations website
- Securities and Exchange Commission (SEC) filings
- Market research reports
Disclaimer: This overview is for informational purposes only and should not be considered investment advice. Please consult with a qualified financial professional before making any investment decisions.
Conclusion:
Insmed Inc. is a promising biopharmaceutical company with a leading position in the LEMS market. The company's launch of Aemcolo has driven significant revenue growth, and it has potential for further expansion. However, investors should consider the company's challenges, including its profitability and competition, before making investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Insmed Inc
Exchange | NASDAQ | Headquaters | Bridgewater, NJ, United States |
IPO Launch date | 2000-06-01 | President, CEO & Chairman | Mr. William H. Lewis J.D., M.B.A. |
Sector | Healthcare | Website | https://www.insmed.com |
Industry | Biotechnology | Full time employees | 912 |
Headquaters | Bridgewater, NJ, United States | ||
President, CEO & Chairman | Mr. William H. Lewis J.D., M.B.A. | ||
Website | https://www.insmed.com | ||
Website | https://www.insmed.com | ||
Full time employees | 912 |
Insmed Incorporated, a biopharmaceutical company, develops and commercializes therapies for patients with serious and rare diseases in the United States, Europe, Japan, and internationally. The company offers ARIKAYCE for the treatment of Mycobacterium avium complex lung disease as part of a combination antibacterial drug regimen for adult patients. It is also developing Brensocatib, an oral reversible inhibitor of dipeptidyl peptidase 1 for the treatment of patients with bronchiectasis and other neutrophil-mediated diseases; and Treprostinil Palmitil Inhalation Powder, an inhaled formulation of a treprostinil prodrug treprostinil palmitil for the treatment of pulmonary hypertension associated with interstitial lung disease and pulmonary arterial hypertension. The company was founded in 1988 and is headquartered in Bridgewater, New Jersey.
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