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GTBP logo GTBP
Upturn stock ratingUpturn stock rating
GTBP logo

GT Biopharma Inc (GTBP)

Upturn stock ratingUpturn stock rating
$2.35
Delayed price
Profit since last BUY-8.2%
upturn advisory
WEAK BUY
BUY since 16 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

04/04/2025: GTBP (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -63.48%
Avg. Invested days 18
Today’s Advisory WEAK BUY
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/04/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 6.23M USD
Price to earnings Ratio -
1Y Target Price 11
Price to earnings Ratio -
1Y Target Price 11
Volume (30-day avg) 936672
Beta 0.57
52 Weeks Range 1.72 - 10.66
Updated Date 04/6/2025
52 Weeks Range 1.72 - 10.66
Updated Date 04/6/2025
Dividends yield (FY) -
Basic EPS (TTM) -7.39

Earnings Date

Report Date 2025-03-24
When Before Market
Estimate -
Actual -1.6895

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -60.59%
Return on Equity (TTM) -131.48%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -3815468
Price to Sales(TTM) -
Enterprise Value -3815468
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.09
Shares Outstanding 2234330
Shares Floating 1665289
Shares Outstanding 2234330
Shares Floating 1665289
Percent Insiders 12.15
Percent Institutions 67.52

Analyst Ratings

Rating 4
Target Price 11
Buy 1
Strong Buy -
Buy 1
Strong Buy -
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

GT Biopharma Inc

stock logo

Company Overview

overview logo History and Background

GT Biopharma, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative immunotherapies based on its TriKEu00ae platform. Founded to address unmet needs in cancer treatment, the company is pioneering novel approaches to harness the power of the immune system to target and eliminate cancer cells.

business area logo Core Business Areas

  • TriKEu00ae Platform: GT Biopharma's core business revolves around its TriKEu00ae (Tri-specific Killer Engager) platform. This technology engineers immune cells to target and kill cancer cells.
  • Clinical Development: The company focuses on advancing its TriKEu00ae-based drug candidates through clinical trials, primarily targeting hematologic malignancies.

leadership logo Leadership and Structure

The leadership team comprises experienced professionals in the biopharmaceutical industry, with a focus on drug development and commercialization. The company structure includes research and development, clinical operations, and administrative functions.

Top Products and Market Share

overview logo Key Offerings

  • GTB-3550 TriKEu00ae: GTB-3550 is a TriKEu00ae-based drug candidate targeting CD33+ hematologic malignancies, including acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). As a clinical-stage product, it does not currently generate revenue. Competitors include companies developing other immunotherapies for AML, such as antibody-drug conjugates (ADCs) and CAR-T therapies.
  • GTB-4550 TriKEu00ae: GTB-4550 is a TriKEu00ae based drug candidate targeting CD33 and CD123. It does not currently generate revenue. Competitors include companies developing other immunotherapies for AML, such as antibody-drug conjugates (ADCs) and CAR-T therapies.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is highly competitive, with a strong focus on developing novel cancer therapies. Immunotherapy is a rapidly growing segment, driven by the potential to offer more effective and less toxic treatments compared to traditional chemotherapy.

Positioning

GT Biopharma is positioned as an innovative immunotherapy company with its proprietary TriKEu00ae platform. Its competitive advantage lies in the potential for TriKEu00ae to overcome limitations of existing immunotherapies by engaging a broader range of immune cells and targeting multiple cancer antigens.

Total Addressable Market (TAM)

The total addressable market for hematologic malignancies is substantial, estimated to be in the billions of dollars. GT Biopharma is positioned to capture a portion of this market with its TriKEu00ae platform, focusing initially on AML and MDS.

Upturn SWOT Analysis

Strengths

  • Proprietary TriKEu00ae platform
  • Potential for broad application across multiple cancer types
  • Experienced management team
  • Focus on unmet medical needs

Weaknesses

  • Clinical-stage company with no current revenue
  • High reliance on successful clinical trial outcomes
  • Limited financial resources compared to larger pharmaceutical companies
  • Risk of competition from established players

Opportunities

  • Successful clinical trial results leading to regulatory approval
  • Partnerships with larger pharmaceutical companies
  • Expansion of TriKEu00ae platform to other cancer indications
  • Increased adoption of immunotherapy in cancer treatment

Threats

  • Failure to achieve positive clinical trial results
  • Competition from more established immunotherapy companies
  • Changes in regulatory landscape
  • Economic downturn impacting funding for biotechnology companies

Competitors and Market Share

competitor logo Key Competitors

  • NK
  • AGEN
  • TCR2

Competitive Landscape

GT Biopharma faces competition from established immunotherapy companies and companies developing alternative therapies for hematologic malignancies. Its TriKEu00ae platform offers a novel approach, but its success depends on demonstrating clinical efficacy and safety.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: GT Biopharma's historical growth is primarily reflected in its clinical development progress and expansion of its TriKEu00ae platform. It has not yet generated significant revenue.

Future Projections: Future growth depends on the success of its clinical trials and potential partnerships. Analyst estimates are necessary for specific projections.

Recent Initiatives: Recent initiatives include advancing GTB-3550 through clinical trials, exploring new TriKEu00ae designs, and seeking collaborations with other companies.

Summary

GT Biopharma is a clinical-stage biopharmaceutical company with a promising TriKEu00ae platform for immunotherapy. The company's success hinges on the results of its clinical trials and its ability to secure partnerships. While the technology is innovative, the company faces significant risks associated with drug development and competition. Success will require strong execution and financial resources.

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Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Press releases
  • Industry reports

Disclaimers:

This analysis is based on publicly available information and is not financial advice. Market share data are estimates and may not be precise. Clinical trial outcomes are inherently uncertain.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About GT Biopharma Inc

Exchange NASDAQ
Headquaters San Francisco, CA, United States
IPO Launch date 2017-09-22
Interim CEO & Executive Chairman Mr. Michael Martin Breen L.L.B.
Sector Healthcare
Industry Biotechnology
Full time employees 1
Full time employees 1

GT Biopharma, Inc., a clinical stage biopharmaceutical company, engages in the development and commercialization of immuno-oncology products based on its proprietary Tri-specific Killer Engager (TriKE) fusion protein immune cell engager technology platform. The company develops GTB-3650, which is in preclinical studies that target CD33 on the surface of myeloid leukemias and an agonistic camelid; GTB-5550 which targets B7-H3 on the surface of advanced solid tumors; GTB-7550, a product candidate in development for the treatment of lupus and other autoimmune disorders. GT Biopharma, Inc. entered a master services agreement with Cytovance Biologics, Inc. to perform biologic development and manufacturing services, and to produce and test compounds; and a license agreement with the Regents of the University of Minnesota to develop and commercialize cancer therapies using TriKE technology. The company was formerly known as OXIS International, Inc. and changed its name to GT Biopharma, Inc. in July 2017. GT Biopharma, Inc. was incorporated in 1965 and is based in Brisbane, California.

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