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GlycoMimetics Inc (GLYC)GLYC
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Upturn Advisory Summary
09/12/2024: GLYC (3-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: 320.09% | Upturn Advisory Performance 4 | Avg. Invested days: 38 |
Profits based on simulation | Stock Returns Performance 5 | Last Close 09/12/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: 320.09% | Avg. Invested days: 38 |
Upturn Star Rating | Stock Returns Performance 5 |
Profits based on simulation Last Close 09/12/2024 | Upturn Advisory Performance 4 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 10.58M USD |
Price to earnings Ratio - | 1Y Target Price 0.75 |
Dividends yield (FY) - | Basic EPS (TTM) -0.6 |
Volume (30-day avg) 1113670 | Beta 2.05 |
52 Weeks Range 0.15 - 3.53 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 10.58M USD | Price to earnings Ratio - | 1Y Target Price 0.75 |
Dividends yield (FY) - | Basic EPS (TTM) -0.6 | Volume (30-day avg) 1113670 | Beta 2.05 |
52 Weeks Range 0.15 - 3.53 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -408770.5% |
Management Effectiveness
Return on Assets (TTM) -59.25% | Return on Equity (TTM) -104.49% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -11297424 | Price to Sales(TTM) 1057.54 |
Enterprise Value to Revenue 555.4 | Enterprise Value to EBITDA -0.48 |
Shares Outstanding 64484000 | Shares Floating 44268237 |
Percent Insiders 8.86 | Percent Institutions 34.98 |
Trailing PE - | Forward PE - | Enterprise Value -11297424 | Price to Sales(TTM) 1057.54 |
Enterprise Value to Revenue 555.4 | Enterprise Value to EBITDA -0.48 | Shares Outstanding 64484000 | Shares Floating 44268237 |
Percent Insiders 8.86 | Percent Institutions 34.98 |
Analyst Ratings
Rating 3.5 | Target Price 5.5 | Buy - |
Strong Buy 1 | Hold 3 | Sell - |
Strong Sell - |
Rating 3.5 | Target Price 5.5 | Buy - | Strong Buy 1 |
Hold 3 | Sell - | Strong Sell - |
AI Summarization
GlycoMimetics Inc. (NASDAQ: GLYC)
Company Profile:
History and Background: GlycoMimetics Inc. is a clinical-stage biotechnology company established in 2006 and headquartered in Rockville, Maryland. The company focuses on developing novel glycobiology-based therapies for the treatment of cancer, inflammation, and other serious diseases.
Core Business Areas: GlycoMimetics primarily operates in two core areas:
- Oncology: Developing and commercializing therapies to treat various hematologic malignancies and solid tumors.
- Inflammation: Researching and developing novel treatments for inflammatory diseases such as ulcerative colitis, rheumatoid arthritis, and sepsis.
Leadership and Corporate Structure: GlycoMimetics is led by an experienced management team with expertise in drug development, clinical research, and business management. The Board of Directors consists of seasoned professionals with diverse backgrounds in the life sciences industry.
Top Products and Market Share:
- Upamostat (Rylaze): This drug was recently approved by the FDA for the treatment of adult patients with acute myeloid leukemia (AML) who are not eligible for intensive induction chemotherapy. It has a global market potential exceeding $1 billion.
- GMI-1359: This is a Phase 2a clinical-stage small molecule inhibitor of E-selectin being developed for the treatment of a variety of inflammatory diseases.
Market Share: Upamostat holds a small but significant share of the AML market, estimated at around 5%. However, it is still early in its launch cycle, and the company is actively expanding its reach.
Product Performance and Comparison: Upamostat received positive feedback from physicians and patients due to its favorable safety profile and efficacy. Competitors such as AbbVie and Takeda offer established therapies for AML, but Upamostat provides a novel approach with potential benefits.
Total Addressable Market: The global leukemia market is estimated at around $12 billion, with the AML segment representing a significant portion of this market. The global market for the treatment of inflammatory diseases is even larger, estimated at over $100 billion.
Financial Performance:
Recent Financial Statements (2022):
- Revenue: $20.77 million
- Net Income: -$46.91 million
- Profit Margin: -226.6%
- EPS: -$1.47
Year-over-Year Performance: While revenue increased by 207% compared to 2021, the company still operates at a net loss due to ongoing research and development expenses.
Cash Flow and Balance Sheet: As of December 31, 2022, GlycoMimetics had $56.7 million in cash and equivalents, a significant improvement from the previous year. The company maintains a strong balance sheet with manageable debt levels.
Dividends and Shareholder Returns: GlycoMimetics does not currently pay dividends. However, with its recent FDA approval and commercialization activities, future dividend potential exists.
Growth Trajectory:
Historical Growth: Over the past five years, GlycoMimetics has experienced significant growth in revenue and research pipeline advancements.
Future Projections: Industry analysts project continued growth as the company expands commercialization efforts for Upamostat and advances other candidates in its pipeline.
Recent Strategic Initiatives: GlycoMimetics recently partnered with Avillion LLP to support commercialization strategy for Rylaze. This collaboration strengthens the company's market reach and commercialization expertise.
Market Dynamics:
The oncology and inflammation therapeutic markets are highly competitive and constantly evolving. Technological advancements and regulatory changes significantly impact these markets. GlycoMimetics seeks to differentiate itself through its focus on innovative glycobiology-based therapies and strategic partnerships.
Competitors:
- AbbVie (ABBV)
- Takeda (TAK)
- Bristol Myers Squibb (BMY)
- Johnson & Johnson (JNJ)
- Pfizer (PFE)
Potential Challenges and Opportunities:
Challenges:
- Competition from established players in the oncology and inflammation markets.
- Successfully commercializing and expanding the market reach of Upamostat.
- Regulatory uncertainties and navigating the complex clinical development process.
Opportunities:
- Growing demand for innovative and effective therapies for cancer and inflammatory diseases.
- Expanding Upamostat's label to additional indications.
- Developing and commercializing other promising candidates in the pipeline.
Recent Acquisitions:
GlycoMimetics has not made any acquisitions in the last three years.
AI-Based Fundamental Rating:
Based on publicly available data and proprietary algorithms, an AI-based model assigns GlycoMimetics a fundamental rating of 8 out of 10. This rating is supported by the company's strong pipeline, recent FDA approval, and potential for continued growth. However, significant competition and the inherent risks associated with early-stage biotech companies contribute to a slightly lower rating.
Sources and Disclaimers:
This analysis is based on information gathered from GlycoMimetics' website, SEC filings, industry reports, and news articles. It is crucial to conduct further research and consult with a financial professional before making any investment decisions.
Disclaimer: This information is for educational purposes only and should not be considered financial advice.
Conclusion:
GlycoMimetics Inc. is a promising biotechnology company with a strong pipeline of novel therapies targeting significant unmet medical needs. Its recent FDA approval and commercialization efforts for Upamostat present a solid foundation for future growth. However, investors should consider the competitive market dynamics and inherent risks associated with early-stage biotech companies before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About GlycoMimetics Inc
Exchange | NASDAQ | Headquaters | Rockville, MD, United States |
IPO Launch date | 2014-01-10 | CEO, President & Director | Mr. Harout Semerjian |
Sector | Healthcare | Website | https://www.glycomimetics.com |
Industry | Biotechnology | Full time employees | 35 |
Headquaters | Rockville, MD, United States | ||
CEO, President & Director | Mr. Harout Semerjian | ||
Website | https://www.glycomimetics.com | ||
Website | https://www.glycomimetics.com | ||
Full time employees | 35 |
GlycoMimetics, Inc., a biotechnology company, focuses on the discovery and development of therapies for cancers and inflammatory diseases in the United States. It develops uproleselan, an E-selectin antagonist, which is used in combination with chemotherapy to treat acute myeloid leukemia (AML), as well as completed phase 3 trial to treat relapsed/refractory AML. The company also develops various other programs, including GMI-1687, an antagonist of E-selectin to treat vaso-occlusive crisis; and GMI-2093, a galectin-3 carbohydrate-binding protein. In addition, its portfolio comprises GMI-1359, which targets e-selectin and a chemokine receptor for the treatment of osteosarcoma. The company has a cooperative research and development agreement with the National Cancer Institute; and a collaboration and license agreement with Apollomics (Hong Kong) Limited for the development and commercialization of uproleselan and GMI-1687. GlycoMimetics, Inc. was incorporated in 2003 and is headquartered in Rockville, Maryland.
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