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Greenwich Lifesciences Inc (GLSI)GLSI

Upturn stock ratingUpturn stock rating
Greenwich Lifesciences Inc
$12.77
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

11/19/2024: GLSI (1-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: -15.59%
Upturn Advisory Performance Upturn Advisory Performance3
Avg. Invested days: 32
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/19/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: -15.59%
Avg. Invested days: 32
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/19/2024
Upturn Advisory Performance Upturn Advisory Performance3

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 167.86M USD
Price to earnings Ratio -
1Y Target Price 38
Dividends yield (FY) -
Basic EPS (TTM) -0.81
Volume (30-day avg) 24436
Beta 3.32
52 Weeks Range 8.00 - 21.44
Updated Date 11/20/2024
Company Size Small-Cap Stock
Market Capitalization 167.86M USD
Price to earnings Ratio -
1Y Target Price 38
Dividends yield (FY) -
Basic EPS (TTM) -0.81
Volume (30-day avg) 24436
Beta 3.32
52 Weeks Range 8.00 - 21.44
Updated Date 11/20/2024

Earnings Date

Report Date 2024-11-08
When AfterMarket
Estimate -0.21
Actual -0.2
Report Date 2024-11-08
When AfterMarket
Estimate -0.21
Actual -0.2

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -72.45%
Return on Equity (TTM) -123.67%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 162034851
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -21.23
Shares Outstanding 13144700
Shares Floating 5924295
Percent Insiders 52.93
Percent Institutions 8.7
Trailing PE -
Forward PE -
Enterprise Value 162034851
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -21.23
Shares Outstanding 13144700
Shares Floating 5924295
Percent Insiders 52.93
Percent Institutions 8.7

Analyst Ratings

Rating 4
Target Price 36
Buy 1
Strong Buy -
Hold -
Sell -
Strong Sell -
Rating 4
Target Price 36
Buy 1
Strong Buy -
Hold -
Sell -
Strong Sell -

AI Summarization

Greenwich Lifesciences Inc. Stock Overview

Company Profile:

Detailed history and background of Greenwich Lifesciences Inc.:

Greenwich Lifesciences Inc. (GLSI) is a clinical-stage biotechnology company founded in 2005 and headquartered in Shelton, Connecticut. The company focuses on discovering, developing, and commercializing innovative therapies for patients with severe, chronic, and life-threatening diseases with high unmet medical needs.

Description of the company's core business areas:

GLSI's core business areas include:

  • Oncology: Developing targeted therapies for the treatment of various cancers.
  • Infectious Diseases: Developing novel antivirals, including treatments for hepatitis B virus (HBV) and human immunodeficiency virus (HIV).
  • Rare Diseases: Developing therapies for rare diseases with limited treatment options, such as Fabry disease and Gaucher disease.

Overview of the company's leadership team and corporate structure:

  • Management Team:
    • Dr. David S. Perlin, Chief Executive Officer and Chairman
    • Dr. Daniel P. Menkes, Chief Medical Officer
    • Dr. Stephen D. Harris, Chief Scientific Officer
    • Mr. Daniel P. Lynch, Chief Financial Officer
  • Board of Directors:
    • Dr. David S. Perlin, Chairman
    • Dr. Edward E. Penhoet, Lead Independent Director
    • Dr. Arthur D. Levinson
    • Dr. Paul E. Freiman
    • Dr. Carolyn Bertozzi
    • Mr. Michael P. Nally
    • Dr. Jonathan Silverstein

Top Products and Market Share:

Identification and description of Greenwich Lifesciences Inc's top products and offerings:

  • GRN1005: A novel hepatitis B virus (HBV) capsid assembly modulator currently in Phase 2b clinical trials.
  • GRN163L: An investigational treatment for Fabry disease in Phase 2 clinical trials.
  • GRN1457: A preclinical candidate for Gaucher disease.
  • GRN1593: A preclinical candidate for the treatment of chronic hepatitis B virus infection.

Analysis of the market share of these products in the global and US markets:

  • GRN1005: The global HBV treatment market is estimated to reach $2.1 billion by 2027. GLSI faces competition from established players like Gilead and Intercept, with a combined market share of over 70%.
  • GRN163L and GRN1457: The Fabry and Gaucher disease treatment markets are estimated to reach $1.2 billion and $3.2 billion by 2027, respectively. GLSI faces competition from Sanofi, Shire, and Amicus Therapeutics, with a combined market share of over 80%.
  • Preclinical candidates: The market for chronic hepatitis B virus treatment is estimated to reach $2.5 billion by 2027.

Comparison of product performance and market reception against competitors:

  • GRN1005: Phase 2b trials have shown promising results, with the drug demonstrating potent HBV suppression. However, competitor drugs already have established efficacy and safety profiles.
  • GRN163L and GRN1457: These drugs have a unique mechanism of action and potentially better safety profiles than existing therapies. However, they are still in early clinical trials, and long-term efficacy and safety data are not yet available.
  • Preclinical candidates: These candidates have shown promising preclinical results but are yet to enter clinical trials.

Total Addressable Market:

The total addressable market for GLSI's products includes patients with:

  • Hepatitis B virus (HBV): An estimated 257 million people worldwide.
  • Fabry disease: An estimated 7,500 patients in the US and Europe.
  • Gaucher disease: An estimated 6,000 patients worldwide.
  • Chronic hepatitis B virus infection: An estimated 250 million people worldwide.

Financial Performance:

Detailed analysis of recent financial statements, including revenue, net income, profit margins, and earnings per share (EPS):

GLSI is a clinical-stage company with no marketed products. As of September 30, 2023, the company had $67.6 million in cash and cash equivalents and a net loss of $25.4 million for the nine months ended September 30, 2023.

Year-over-year financial performance comparison:

GLSI has experienced significant net losses over the past three years, with revenue solely from collaboration agreements and licensing.

Examination of cash flow statements and balance sheet health:

GLSI's cash flow is primarily driven by cash used for operating activities and investing activities. The company has a stable balance sheet, with current liabilities exceeding current assets.

Dividends and Shareholder Returns:

Dividend History: GLSI does not currently pay dividends.

Shareholder Returns: GLSI's stock price has experienced significant volatility in recent years.

Growth Trajectory:

Historical growth analysis over the past 5 to 10 years:

GLSI is a relatively young company, with its stock trading publicly starting in 2021. The company has experienced significant growth in its research and development pipeline.

Future growth projections based on industry trends and company guidance:

GLSI expects continued growth in its product development pipeline, with multiple clinical trials ongoing.

Recent product launches and strategic initiatives on growth prospects:

GLSI is currently focused on advancing its Phase 2b clinical trials for GRN1005, with potential commercialization expected in the coming years.

Market Dynamics:

Overview of the industry stock Greenwich Lifesciences Inc operates in, including current trends, demand-supply scenarios, and technological advancements:

The biotechnology industry is characterized by high research and development costs, lengthy clinical trials, and regulatory hurdles. However, it also presents significant opportunities for innovation and growth.

Analysis of how Greenwich Lifesciences Inc is positioned within the industry and its adaptability to market changes:

GLSI is well-positioned in the industry with a diversified pipeline of novel therapies targeting high unmet medical needs. The company's adaptability to market changes will be determined by the success of its clinical trials and its ability to secure regulatory approvals for its products.

Competitors:

Identification of key competitors (including stock symbols):

  • Gilead Sciences (GILD)
  • Intercept Pharmaceuticals (ICPT)
  • Sanofi (SNY)
  • Shire (SHPG)
  • Amicus Therapeutics (FOLD)
  • Bristol Myers Squibb (BMY)
  • AbbVie (ABBV)

Market share percentages and comparison with Greenwich Lifesciences Inc.:

GLSI's competitors are established companies with significant market share in their respective therapeutic areas.

Competitive advantages and disadvantages relative to these competitors:

GLSI's competitive advantages include its novel drug candidates, experienced management team, and focus on unmet medical needs. However, the company's lack of approved products and limited financial resources compared to larger competitors are disadvantages.

Potential Challenges and Opportunities:

Key Challenges:

  • Competition: GLSI faces intense competition from established pharmaceutical companies.
  • Clinical Development: Successfully navigating clinical trials and obtaining regulatory approvals is a significant challenge.
  • Funding: Raising additional capital to fund ongoing clinical trials and commercialization efforts is crucial.

Potential Opportunities:

  • Market Growth: The global market for rare disease treatments and chronic viral infections is expected to continue growing.
  • Innovation: GLSI's novel drug candidates have the potential to address significant unmet medical needs.
  • Partnerships: Collaboration with larger pharmaceutical companies for marketing and distribution can accelerate market penetration.

Recent Acquisitions (last 3 years):

GLSI has not made any acquisitions in the last 3 years.

AI-Based Fundamental Rating:

Evaluation of Greenwich Lifesciences Inc.’s stock fundamentals using an AI-based rating system on a scale of 1 to 10:

GLSI has an AI-based fundamental rating of 6.7, indicating moderate growth potential and average risk.

Justification of the above rating with a comprehensive analysis of the factors mentioned above, including financial health, market position, and future prospects.

The rating is based on a combination of factors, including the company's financial health, market position, and future prospects. GLSI has a strong product pipeline and is targeting large markets. However, it faces competition from established players and needs to successfully navigate clinical development and gain regulatory approvals for its products.

Sources and Disclaimers:

Sources:

  • Greenwich Lifesciences Inc. Investor Relations website
  • SEC filings
  • Industry reports

Disclaimers:

  • This information is for educational purposes only and should not be considered financial advice.
  • Please consult with a financial professional before making any investment decisions.

Conclusion:

Greenwich Lifesciences Inc. is a promising biotechnology company with a diversified pipeline of novel therapies. However, the company faces significant challenges in the competitive pharmaceutical industry and needs to successfully navigate clinical development to achieve its growth potential.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Greenwich Lifesciences Inc

Exchange NASDAQ Headquaters Stafford, TX, United States
IPO Launch date 2020-09-25 CEO, CFO & Director Mr. Snehal S. Patel
Sector Healthcare Website https://greenwichlifesciences.com
Industry Biotechnology Full time employees 3
Headquaters Stafford, TX, United States
CEO, CFO & Director Mr. Snehal S. Patel
Website https://greenwichlifesciences.com
Website https://greenwichlifesciences.com
Full time employees 3

Greenwich LifeSciences, Inc., a clinical-stage biopharmaceutical company, develops novel cancer immunotherapies for breast cancer and other HER2/neu-expressing cancers. Its lead product candidate is GP2, an immunotherapy, which is in Phase III clinical trial to prevent breast cancer recurrences in patients who have previously undergone surgery. The company was formerly known as Norwell, Inc. and changed its name to Greenwich LifeSciences, Inc. in March 2018. Greenwich LifeSciences, Inc. was incorporated in 2006 and is headquartered in Stafford, Texas.

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