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Foghorn Therapeutics Inc (FHTX)FHTX
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Upturn Advisory Summary
08/29/2024: FHTX (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -80.63% | Upturn Advisory Performance 1 | Avg. Invested days: 31 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 08/29/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -80.63% | Avg. Invested days: 31 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 08/29/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 544.43M USD |
Price to earnings Ratio - | 1Y Target Price 15.5 |
Dividends yield (FY) - | Basic EPS (TTM) -1.93 |
Volume (30-day avg) 108190 | Beta 3.11 |
52 Weeks Range 2.70 - 10.25 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 544.43M USD | Price to earnings Ratio - | 1Y Target Price 15.5 |
Dividends yield (FY) - | Basic EPS (TTM) -1.93 | Volume (30-day avg) 108190 | Beta 3.11 |
52 Weeks Range 2.70 - 10.25 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -245.69% | Operating Margin (TTM) -351.83% |
Management Effectiveness
Return on Assets (TTM) -17.77% | Return on Equity (TTM) -470.38% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 300172965 | Price to Sales(TTM) 15.47 |
Enterprise Value to Revenue 8.53 | Enterprise Value to EBITDA -1.21 |
Shares Outstanding 55328700 | Shares Floating 28817377 |
Percent Insiders 19.07 | Percent Institutions 71.43 |
Trailing PE - | Forward PE - | Enterprise Value 300172965 | Price to Sales(TTM) 15.47 |
Enterprise Value to Revenue 8.53 | Enterprise Value to EBITDA -1.21 | Shares Outstanding 55328700 | Shares Floating 28817377 |
Percent Insiders 19.07 | Percent Institutions 71.43 |
Analyst Ratings
Rating 4.43 | Target Price 15.25 | Buy 2 |
Strong Buy 4 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.43 | Target Price 15.25 | Buy 2 | Strong Buy 4 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Foghorn Therapeutics Inc. (FHTX) Overview
Company Profile:
History and Background:
Foghorn Therapeutics Inc. (FHTX) is a clinical-stage biopharmaceutical company founded in 2013 and headquartered in Cambridge, Massachusetts. Their mission is to develop best-in-class gene therapies for chronic liver and cardiometabolic diseases. They utilize adeno-associated virus (AAV) vector technology to deliver therapeutic genes to specific tissues in the body.
Core Business Areas:
- Gene Therapy Development: FHTX focuses on developing gene therapies for chronic liver and cardiometabolic diseases, including type 1 diabetes (T1D), hemophilia A and B, and alpha-1 antitrypsin deficiency (AATD).
- AAV Vector Technology: They leverage AAV vector technology, which delivers therapeutic genes directly to target tissues with high efficiency and specificity.
Leadership and Corporate Structure:
- Leadership Team:
- Adrian Woolf, M.D. - President and Chief Executive Officer
- Kevin R. Ludlow - Chief Financial Officer
- Eric J. Huang, Ph.D. - Chief Scientific Officer
- Board of Directors:
- Michael G. Kaplitt, M.D., Ph.D. - Chairman
- Adrian Woolf, M.D.
- Susan B. Jha, M.D.
- Bruce Booth, Ph.D.
- Mary E. Beckerle, M.D.
- Daniel H. O'Day
- Catherine Stehman-Breen
Top Products and Market Share:
- FHTX-001: A potential one-time gene therapy for hemophilia A, currently in Phase 1/2 clinical trials.
- FHTX-007: A potential one-time gene therapy for T1D, currently in Phase 1/2 clinical trials.
- FHTX-017: A potential one-time gene therapy for AATD, currently in Phase 1 clinical trials.
- Market Share: FHTX is still in the early stages of development and currently does not hold a significant market share in the gene therapy space. However, they have the potential to capture a significant share in the future as their leading candidates progress through clinical trials and reach commercialization.
Total Addressable Market:
- Global Gene Therapy Market: Estimated to reach $37.1 billion by 2027.
- U.S. Gene Therapy Market: Estimated to reach $26.1 billion by 2027.
Financial Performance:
- Revenue: As a pre-commercial stage company, FHTX currently has no product revenue.
- Net Income: FHTX is currently not profitable and reports net losses due to R&D expenses.
- Profit Margins: N/A.
- Earnings per Share (EPS): N/A.
Dividends and Shareholder Returns:
- Dividend History: FHTX does not currently pay dividends.
- Shareholder Returns: FHTX stock has experienced significant volatility since its IPO in 2020. Overall, shareholder returns have been negative.
Growth Trajectory:
- Historical Growth: FHTX has shown steady growth in R&D activities and pipeline development.
- Future Growth Projections: The company anticipates significant growth potential as its lead candidates progress through clinical trials and reach commercialization.
- Recent Developments: FHTX has several ongoing clinical trials and recently expanded its partnership with Verve Therapeutics to develop additional gene therapies for cardiovascular diseases.
Market Dynamics:
- Industry Trends: The gene therapy market is experiencing rapid growth, driven by technological advancements and increasing demand for personalized medicine.
- Demand-Supply Scenario: The demand for gene therapies is expected to continue increasing, while the supply is still limited.
- FHTX's Positioning: FHTX is well-positioned to benefit from the growing gene therapy market with its innovative platform and promising pipeline of candidates.
Competitors:
- Main Competitors:
- Intellia Therapeutics (NTLA)
- Editas Medicine (EDIT)
- CRISPR Therapeutics (CRSP)
- Beam Therapeutics (BEAM)
- Verve Therapeutics (VERV)
- Market Share: Most competitors have not yet reached commercialization stage, making direct market share comparisons challenging.
- Competitive Advantages: FHTX's proprietary AAV vector technology platform and lead candidates in attractive therapeutic areas offer potential competitive advantages.
- Disadvantages: FHTX's late-stage clinical development program compared to some competitors might pose a challenge.
Key Challenges and Opportunities:
Challenges:
- Clinical Development Risks: FHTX's lead candidates are still in early-stage clinical trials, and their success is not guaranteed.
- Competition: FHTX faces intense competition from established and emerging players in the gene therapy space.
- Regulatory Approvals: Obtaining regulatory approvals for gene therapies is a complex and time-consuming process.
Opportunities:
- Large Market Potential: The gene therapy market offers significant growth potential for FHTX.
- Promising Pipeline: FHTX has a robust pipeline of innovative gene therapy candidates with the potential to address significant unmet medical needs.
- Strategic Partnerships: FHTX's collaboration with Verve Therapeutics opens up new opportunities in the cardiovascular space.
Recent Acquisitions:
- FHTX has not completed any acquisitions in the past 3 years.
AI-Based Fundamental Rating:
Rating: 7/10
Justification: FHTX has a promising pipeline of gene therapy candidates targeting large markets with significant unmet needs. The company has a proprietary AAV vector technology platform and strong leadership team. However, FHTX faces risks associated with clinical development and competition. The assigned rating reflects the company's potential for growth balanced against these challenges.
Sources and Disclaimers:
- Information for this overview was gathered from the following sources:
- Foghorn Therapeutics Inc. website (www.foghorntx.com)
- Securities and Exchange Commission (SEC) filings
- Market research reports
- News articles
- This information is for educational purposes only and should not be considered investment advice. It is essential to conduct your own due diligence before making any investment decisions.
Disclaimer:
I am an AI chatbot and cannot provide financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Foghorn Therapeutics Inc
Exchange | NASDAQ | Headquaters | Cambridge, MA, United States |
IPO Launch date | 2020-10-23 | President, CEO & Director | Mr. Adrian H. B. Gottschalk |
Sector | Healthcare | Website | https://foghorntx.com |
Industry | Biotechnology | Full time employees | 116 |
Headquaters | Cambridge, MA, United States | ||
President, CEO & Director | Mr. Adrian H. B. Gottschalk | ||
Website | https://foghorntx.com | ||
Website | https://foghorntx.com | ||
Full time employees | 116 |
Foghorn Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of medicines targeting genetically determined dependencies within the chromatin regulatory system in the United States. The company uses its proprietary Gene Traffic Control platform to identify, validate, and potentially drug targets within the system. It develops FHD-286, a small molecule inhibitor of the enzymatic activity of BRG1 and BRM that is in phase I for the treatment of relapsed and/or refractory acute myeloid leukemia/myelodysplastic syndrome. The company is also developing therapies for mutant cancers, such as Non-Small Cell Lung, bladder, endometrial, colorectal, and melanoma cancers; and dependent cancers, including prostate cancer and diffuse large b-cell lymphoma. It has a research collaboration and license agreement with Merck Sharp & Dohme Corp. to discover and develop novel oncology therapeutics against a transcription factor target; and Eli Lilly and Company for developing FHD-909, a selective ATPase inhibitor of BRM. Foghorn Therapeutics Inc. was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
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