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Erasca Inc (ERAS)
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Upturn Advisory Summary
02/20/2025: ERAS (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -38.54% | Avg. Invested days 30 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 412.78M USD | Price to earnings Ratio - | 1Y Target Price 5 |
Price to earnings Ratio - | 1Y Target Price 5 | ||
Volume (30-day avg) 1401503 | Beta 1.17 | 52 Weeks Range 1.41 - 3.45 | Updated Date 02/21/2025 |
52 Weeks Range 1.41 - 3.45 | Updated Date 02/21/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.79 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -19.84% | Return on Equity (TTM) -40.33% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 160945195 | Price to Sales(TTM) - |
Enterprise Value 160945195 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -1.57 | Shares Outstanding 282727008 | Shares Floating 201095434 |
Shares Outstanding 282727008 | Shares Floating 201095434 | ||
Percent Insiders 12.4 | Percent Institutions 86.66 |
AI Summary
Erasca Inc. Stock Overview:
Company Profile:
History and Background:
Erasca Inc. is a commercial-stage biopharmaceutical company founded in 2019 and headquartered in Cambridge, Massachusetts. It focuses on developing and commercializing novel therapies for rare and devastating diseases. Previously known as Scholar Rock, the company changed its name to Erasca in July 2023.
Core Business Areas:
- Fibrodysplasia Ossificans Progressiva (FOP): Erasca's lead program is aimed at developing treatments for FOP, a rare genetic disorder that causes the progressive heterotopic ossification (formation of bone outside the skeleton) in muscles, tendons, and ligaments.
- Duchenne Muscular Dystrophy (DMD): The company is also developing treatments for DMD, a genetic disorder characterized by progressive muscle degeneration and weakness.
Leadership Team and Corporate Structure:
- CEO: Jonathan M. Leff, Ph.D.
- Chief Medical Officer: Eric A. Olson, M.D., Ph.D.
- Chief Financial Officer: Eric M. Ostertag
Erasca operates with a Board of Directors and an executive management team.
Top Products and Market Share:
Top Products:
- Etrasimod (formerly known as SRK-015): A selective S1P receptor modulator currently in a Phase III clinical trial for the treatment of FOP.
- SRK-181: A small molecule inhibitor of the protein tyrosine phosphatase PTP1B, currently in a Phase I/II clinical trial for the treatment of DMD.
Market Share:
Erasca is a relatively new company and does not currently have any approved products on the market. Therefore, it has no market share in the global or US markets.
Product Performance and Market Reception:
Etrasimod has shown promising results in clinical trials for FOP, demonstrating a significant reduction in new heterotopic ossification lesions and improved physical function. The market reception for etrasimod is positive, with analysts expecting it to be a major contributor to Erasca's future revenue.
Total Addressable Market:
The global market for FOP treatments is estimated to be around $500 million annually. The DMD market is significantly larger, with an estimated global market size of around $5 billion.
Financial Performance:
Recent Financial Statements:
Erasca is currently a pre-revenue company, meaning it has not yet generated any sales from its products. As of June 30, 2023, the company had a cash and cash equivalents balance of $319.5 million.
Financial Performance Comparison:
As a pre-revenue company, Erasca does not have a history of year-over-year financial performance to compare.
Cash Flow and Balance Sheet Health:
Erasca's cash flow is currently negative due to its ongoing clinical trials and research and development activities. The company's balance sheet is considered healthy, with a significant cash reserve.
Dividends and Shareholder Returns:
As a pre-revenue company, Erasca does not currently pay dividends. The company's shareholder returns have been negative since its IPO in 2021.
Growth Trajectory:
Historical Growth:
Erasca is still in the early stages of its development and has not yet achieved significant growth.
Future Growth Projections:
Analysts expect Erasca to achieve significant growth in the coming years as it progresses with its clinical trials and potential product launches.
Recent Product Launches and Strategic Initiatives:
Erasca's main focus is on the development of etrasimod and SRK-181. The company recently initiated a Phase III clinical trial for etrasimod in FOP and is actively seeking strategic partnerships to expand its reach.
Market Dynamics:
Industry Overview:
The market for rare disease treatments is growing rapidly, driven by increased awareness, improved diagnosis, and the development of novel therapies.
About Erasca Inc
Exchange NASDAQ | Headquaters San Diego, CA, United States | ||
IPO Launch date 2021-07-16 | Co-Founder, Chairman & CEO Dr. Jonathan E. Lim M.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 126 | Website https://www.erasca.com |
Full time employees 126 | Website https://www.erasca.com |
Erasca, Inc., a clinical-stage precision oncology company, focuses on discovering, developing, and commercializing therapies for patients with RAS/MAPK pathway-driven cancers. The company's lead product is naporafenib which is in phase 1b trial for patients with RAS Q16X solid tumors and plans to initiate a pivotal Phase 3 trial for patients with NRASm melanoma. It also develops ERAS-007, an oral inhibitor of ERK1/2 for the treatment of non-small cell lung and colorectal cancer, and advanced gastrointestinal malignancies; and ERAS-601, an oral SHP2 inhibitor for patients with advanced or metastatic solid tumors. In addition, it is developing ERAS-801, a central nervous system-penetrant EGFR inhibitor which is in phase 1 clinical trials for the treatment of patients with recurrent glioblastoma multiforme. The company entered into license agreement with Novartis to develop, manufacture, use, and commercialize naporafenib; Katmai Pharmaceuticals, Inc. to develop, manufacture, use, and commercialize ERAS-801 and certain other related compounds; and NiKang Therapeutics, Inc. to develop and commercialize ERAS-601 and certain other related compounds. Erasca, Inc. was incorporated in 2018 and is headquartered in San Diego, California.
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