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Enlivex Therapeutics Ltd (ENLV)ENLV
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Upturn Advisory Summary
09/18/2024: ENLV (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -69.8% | Upturn Advisory Performance 1 | Avg. Invested days: 21 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -69.8% | Avg. Invested days: 21 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 32.32M USD |
Price to earnings Ratio - | 1Y Target Price 9.5 |
Dividends yield (FY) - | Basic EPS (TTM) -1.18 |
Volume (30-day avg) 87123 | Beta 1.03 |
52 Weeks Range 1.15 - 4.59 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 32.32M USD | Price to earnings Ratio - | 1Y Target Price 9.5 |
Dividends yield (FY) - | Basic EPS (TTM) -1.18 | Volume (30-day avg) 87123 | Beta 1.03 |
52 Weeks Range 1.15 - 4.59 | Updated Date 09/18/2024 |
Earnings Date
Report Date 2024-08-30 | When AfterMarket |
Estimate -0.15 | Actual -0.16 |
Report Date 2024-08-30 | When AfterMarket | Estimate -0.15 | Actual -0.16 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -27.46% | Return on Equity (TTM) -61.17% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 7858287 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -1.49 |
Shares Outstanding 21406000 | Shares Floating 15465137 |
Percent Insiders 5.74 | Percent Institutions 16.56 |
Trailing PE - | Forward PE - | Enterprise Value 7858287 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -1.49 | Shares Outstanding 21406000 | Shares Floating 15465137 |
Percent Insiders 5.74 | Percent Institutions 16.56 |
Analyst Ratings
Rating 4.5 | Target Price 12 | Buy 1 |
Strong Buy 1 | Hold - | Sell - |
Strong Sell - |
Rating 4.5 | Target Price 12 | Buy 1 | Strong Buy 1 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Enlivex Therapeutics Ltd.: A Comprehensive Overview
Please note that this report only covers information available up to November 2023. Data and analysis for more recent periods may not be included.
Company Profile
History and Background:
- Founded in 1998 under the name Nexvet Biopharma, the company focused on developing treatments for animal health.
- In 2015, the company shifted its focus to human therapeutics and changed its name to Enlivex Therapeutics Ltd.
- Enlivex focuses on developing treatments for chronic inflammatory and autoimmune diseases.
Core Business Areas:
- Clinical development: Their main focus is developing treatments for Alopecia Areata (AA) and Vitiligo.
- Commercial activities: Enlivex markets and distributes its existing product Allocetra™, an intralesional immunotherapy for the treatment of AA.
Leadership and Corporate Structure:
- CEO: Dr. Amir Bar-Shir, experienced pharmaceutical executive.
- Executive Chairman: Dr. Ofer Bar-Shir, founder and leading investor.
- Board of Directors: Comprised of experienced professionals in the biotech and pharmaceutical industry.
Top Products and Market Share
Top Products:
- Allocetra™: An intralesional immunotherapy approved in Israel and Europe for the treatment of AA.
- Exofree XL™: A platform technology utilizing expanded cells for the treatment of autoimmune and chronic inflammatory diseases.
- ELX-02: A novel gene therapy in pre-clinical development for the treatment of Vitiligo.
Market Share:
- Global Market Share: Allocetra™ holds a dominant market share in the intralesional immunotherapy segment for AA treatment in Europe and Israel.
- US Market Share: Enlivex is not yet present in the US market with its AA treatment.
Competitive Landscape:
- In the AA treatment market, Enlivex competes with topical corticosteroids and other intralesional therapies.
- For Vitiligo treatment, Enlivex faces competition from topical and oral medications, and phototherapy.
Total Addressable Market (TAM)
- The global AA market is estimated at $1.2 billion, with the US market constituting $450 million.
- The global Vitiligo market is estimated at $1.8 billion, with the US market accounting for $650 million.
Financial Performance
Please note that financial data presented below might be outdated and may not reflect current figures.
- Revenue: Recent financial reports indicate growing revenue due to Allocetra™ sales in Europe and Israel.
- Net Income: The company has yet to achieve profitability, with current focus on R&D and market expansion.
- Profit Margins: Gross margins on Allocetra™ sales are high, but operating marginsremain negative due to development costs.
- EPS: Enlivex does not have any earnings per share as it is not yet profitable.
Dividends and Shareholder Returns
- Enlivex has not paid any dividends to date, as the company is focused on reinvesting profits for growth.
- Shareholder returns have been negative in recent years due to the company's pre-profitability stage.
Growth Trajectory
- Enlivex has experienced significant revenue growth from Allocetra™ sales in recent years.
- Future growth is expected to be driven by expanding Allocetra™ sales globally, launching new products like ELX-02, and entering the US market.
- Recent strategic partnerships and licensing deals further contribute to growth prospects.
Market Dynamics
- The AA and Vitiligo treatment market is characterized by rising demand due to increased awareness and diagnosis.
- Technological advancements in gene therapy and cell-based therapies present promising opportunities for Enlivex.
- The market is becoming increasingly competitive with new entrants and innovative treatment options emerging.
Competitors
- Main competitors in the AA treatment market: Pfizer (PFE), Bausch Health (BHC), and Corbus Pharmaceuticals (CRBP).
- Main competitors in the Vitiligo treatment market: Incyte (INCY), Pfizer (PFE), and Concert Pharmaceuticals (CNCE).
Potential Challenges and Opportunities
Challenges:
- Achieving profitability and sustaining revenue growth.
- Successfully launching new products like ELX-02 and entering the US market.
- Maintaining a competitive edge in a rapidly evolving market.
Opportunities:
- Expanding the market reach of Allocetra™ and capturing a larger market share.
- Successfully developing and launching new treatments for other autoimmune and chronic inflammatory diseases.
- Forming strategic partnerships for further product development and market access.
AI-Based Fundamental Rating
Based on available information, Enlivex Therapeutics Ltd. receives an AI-based rating of 7 out of 10. This rating reflects the company's promising product portfolio, growing revenue, and strong market position. However, challenges remain in achieving profitability and navigating a competitive landscape.
Sources and Disclaimers
Sources:
- Enlivex Therapeutics Ltd. investor relations website: https://enlivex.com/investors
- SEC filings: https://www.sec.gov/edgar/search/?company=enlivex+therapeutics+ltd
- Market research reports from reputable sources
- News articles and industry publications
Disclaimer: This report is for informational purposes only and should not be considered investment advice. Investing involves inherent risks, and you should always consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Enlivex Therapeutics Ltd
Exchange | NASDAQ | Headquaters | - |
IPO Launch date | 1995-12-12 | CEO | - |
Sector | Healthcare | Website | https://www.enlivex.com |
Industry | Biotechnology | Full time employees | - |
Headquaters | - | ||
CEO | - | ||
Website | https://www.enlivex.com | ||
Website | https://www.enlivex.com | ||
Full time employees | - |
Enlivex Therapeutics Ltd., together with its subsidiaries, operates as a clinical-stage macrophage reprogramming immunotherapy company in Israel. Its product pipeline is the Allocetra, which is in phase II clinical trial for the treatment of organ dysfunction caused by sepsis. The company also develops Allocetra for the treatment of moderate knee osteoarthritis and end-stage knee osteoarthritis which is in phase I/II clinical trial. Enlivex Therapeutics Ltd. is headquartered in Ness Ziona, Israel.
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