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DYAI logo DYAI
Upturn stock ratingUpturn stock rating
DYAI logo

Dyadic International Inc (DYAI)

Upturn stock ratingUpturn stock rating
$1.4
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
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Upturn Advisory Summary

03/11/2025: DYAI (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type Stock
Historic Profit -60.17%
Avg. Invested days 24
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 03/11/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 33.60M USD
Price to earnings Ratio -
1Y Target Price 6
Price to earnings Ratio -
1Y Target Price 6
Volume (30-day avg) 38309
Beta 0.72
52 Weeks Range 0.93 - 2.67
Updated Date 03/30/2025
52 Weeks Range 0.93 - 2.67
Updated Date 03/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.27

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date 2025-03-26
When Before Market
Estimate -
Actual -0.052

Profitability

Profit Margin -
Operating Margin (TTM) -528.5%

Management Effectiveness

Return on Assets (TTM) -46.28%
Return on Equity (TTM) -127.38%

Valuation

Trailing PE -
Forward PE 15.82
Enterprise Value 37328002
Price to Sales(TTM) 11.88
Enterprise Value 37328002
Price to Sales(TTM) 11.88
Enterprise Value to Revenue 10.68
Enterprise Value to EBITDA -2.93
Shares Outstanding 29477600
Shares Floating 18981241
Shares Outstanding 29477600
Shares Floating 18981241
Percent Insiders 30.21
Percent Institutions 16.01

Analyst Ratings

Rating 4
Target Price 6
Buy 1
Strong Buy -
Buy 1
Strong Buy -
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Dyadic International Inc

stock logo

Company Overview

overview logo History and Background

Dyadic International Inc. was founded in 1979. Initially focused on industrial enzymes, it transitioned to developing and commercializing the C1 gene expression platform for biopharmaceutical and industrial applications. Significant milestones include the development and validation of the C1 technology and partnerships with various companies for research and development.

business area logo Core Business Areas

  • C1 Technology Platform: Dyadic's core business revolves around its patented C1 gene expression platform, a fungal-based technology for producing enzymes and other proteins used in the biopharmaceutical, animal health, and industrial biotechnology industries.

leadership logo Leadership and Structure

Mark Emalfarb serves as the Chief Executive Officer and founder. The company operates with a management team focused on research and development, business development, and strategic partnerships. They rely heavily on collaborative research agreements.

Top Products and Market Share

overview logo Key Offerings

  • C1 Expression Platform: The C1 platform is Dyadic's primary offering. It allows for rapid and cost-effective production of various proteins and enzymes. C1 platform has partnered research programs for human and animal vaccines, biosimilars and pharmaceutical proteins. Competitors include companies using mammalian cell culture (e.g., CHO cells), E. coli, and yeast-based expression systems (e.g., Pichia pastoris). Difficult to ascertain market share due to its position as technology platform used within other products.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical and industrial enzyme markets are experiencing growth driven by increasing demand for biologics, vaccines, and sustainable industrial processes. Advances in gene expression technologies and biomanufacturing are shaping the competitive landscape.

Positioning

Dyadic positions itself as a provider of a cost-effective and scalable alternative to traditional expression systems. Its C1 platform aims to improve the economics and efficiency of biomanufacturing.

Total Addressable Market (TAM)

The TAM for biopharmaceutical manufacturing is expected to reach hundreds of billions of dollars. Dyadic's platform is positioned to capture a portion of this market by offering a more efficient and cost-effective production method. Exact TAM quantification for C1 is difficult but is related to the recombinant protein production market.

Upturn SWOT Analysis

Strengths

  • Proprietary C1 gene expression platform
  • Potential for lower production costs compared to traditional methods
  • Scalability of the C1 platform
  • Partnerships with established companies

Weaknesses

  • Reliance on partnerships for revenue generation
  • Limited number of commercialized products directly attributable to Dyadic
  • Dependence on successful validation and adoption of C1 platform
  • Limited financial resources compared to larger competitors

Opportunities

  • Expanding applications of C1 platform in biopharmaceuticals and industrial enzymes
  • Increased demand for cost-effective biomanufacturing solutions
  • Strategic alliances and licensing agreements
  • Developing proprietary products based on C1 technology

Threats

  • Competition from established expression systems
  • Regulatory hurdles for new biomanufacturing processes
  • Potential obsolescence of technology
  • Failure of partnerships to yield commercial success

Competitors and Market Share

competitor logo Key Competitors

  • Thermo Fisher Scientific (TMO)
  • Merck KGaA (MRK.DE)
  • Danaher Corporation (DHR)

Competitive Landscape

Dyadic's C1 platform offers a potential cost advantage, but it faces competition from established players with well-validated and widely adopted technologies. Differentiation through specialized applications and strategic partnerships is crucial.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical Growth has been inconsistent with limited product sales and fluctuating revenues tied to partnership agreements and licensing fees. Therefore, no specific growth data.

Future Projections: Future Projections are dependent on the success of ongoing research collaborations and the commercialization of products developed using the C1 platform. No external estimates provided for the company.

Recent Initiatives: Focus on developing C1-based solutions for COVID-19 vaccines and therapeutics, expansion of animal health applications, and collaborations with pharmaceutical companies.

Summary

Dyadic International Inc. is a biotech company with a promising C1 gene expression platform. The company faces challenges due to its dependence on licensing agreements, but its unique technology offers cost and scalability advantages. Future success hinges on the successful development and commercialization of products through ongoing partnerships and internal development efforts. Continued validation of C1 platform and financial stability are key to long-term growth.

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Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Third-party financial data providers

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Investment decisions should be based on thorough research and consultation with a qualified financial advisor. Market share data is approximate.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Dyadic International Inc

Exchange NASDAQ
Headquaters Jupiter, FL, United States
IPO Launch date 2004-11-05
Founder, CEO, President & Director Mr. Mark A. Emalfarb
Sector Healthcare
Industry Biotechnology
Full time employees -
Full time employees -

Dyadic International, Inc., a biotechnology platform company, develops, produces, and sells enzymes and other proteins in the United States and internationally. It utilizes C1-cell protein production platform based on an industrially proven microorganism (C1) for the development and production of biologic products including enzymes and other proteins for human and animal health. The company offers DYAI-100, SARS-CoV-2-RBD antigen vaccine candidate towards a first-in-human Phase 1 clinical trial to demonstrate the safety in humans of a protein produced using the C1 platform. It has also developed the Dapibus thermophilic, a filamentous fungal-based microbial protein production platform to enable the development and large-scale manufacture of cost-effective proteins, metabolites, and other biologic products for use in non-pharmaceutical applications, including food, nutrition, and wellness. The company has a research and development agreement with VTT Technical Research Centre of Finland, Ltd.; license agreement with South Africa's Rubic One Health; Joint Development Agreement with a Global Food Ingredient Company; and sub-license agreement with Abic Biological Laboratories Ltd., Alphazyme, LLC, and Abic Biological Laboratories Ltd. Dyadic International, Inc. was founded in 1979 and is headquartered in Jupiter, Florida.

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