Cancel anytime
Dianthus Therapeutics Inc. (DNTH)DNTH
- BUY Advisory
- Profitable SELL
- Loss-Inducing SELL
- Profit
- Loss
- PASS (Skip invest)*
- ALL
- YEAR
- MONTH
- WEEK
Upturn Advisory Summary
09/18/2024: DNTH (1-star) is a SELL. SELL since 2 days. Profits (-1.07%). Updated daily EoD!
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: SELL |
Profit: -25.68% | Upturn Advisory Performance 1 | Avg. Invested days: 46 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: SELL |
Profit: -25.68% | Avg. Invested days: 46 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 762.92M USD |
Price to earnings Ratio - | 1Y Target Price 50.33 |
Dividends yield (FY) - | Basic EPS (TTM) -1.93 |
Volume (30-day avg) 136745 | Beta - |
52 Weeks Range 6.58 - 33.77 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 762.92M USD | Price to earnings Ratio - | 1Y Target Price 50.33 |
Dividends yield (FY) - | Basic EPS (TTM) -1.93 | Volume (30-day avg) 136745 | Beta - |
52 Weeks Range 6.58 - 33.77 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -1191.84% |
Management Effectiveness
Return on Assets (TTM) -19.84% | Return on Equity (TTM) -27.33% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 402618776 | Price to Sales(TTM) 185.26 |
Enterprise Value to Revenue 97.77 | Enterprise Value to EBITDA -7.35 |
Shares Outstanding 29354300 | Shares Floating 13331558 |
Percent Insiders 8.83 | Percent Institutions 101.96 |
Trailing PE - | Forward PE - | Enterprise Value 402618776 | Price to Sales(TTM) 185.26 |
Enterprise Value to Revenue 97.77 | Enterprise Value to EBITDA -7.35 | Shares Outstanding 29354300 | Shares Floating 13331558 |
Percent Insiders 8.83 | Percent Institutions 101.96 |
Analyst Ratings
Rating 4.8 | Target Price 24 | Buy 2 |
Strong Buy 8 | Hold - | Sell - |
Strong Sell - |
Rating 4.8 | Target Price 24 | Buy 2 | Strong Buy 8 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Dianthus Therapeutics Inc. - A Comprehensive Overview
Company Profile:
History & Background:
Dianthus Therapeutics Inc. is a clinical-stage biopharmaceutical company established in 2017 and headquartered in Cambridge, Massachusetts. Its primary focus lies in developing and commercializing novel therapeutic protein fusions for the treatment of severe hematological diseases and genetic disorders.
Core Business Areas:
Dianthus utilizes a proprietary platform technology called 3D-PTM to produce its therapeutic protein fusions. These protein fusions are designed to address the limitations of existing therapies by offering improved efficacy, safety, and targeted delivery. The company's pipeline currently focuses on:
- Treatment of Severe Hematological Diseases: This includes developing novel therapies for rare blood diseases such as sickle cell disease and beta-thalassemia.
- Treatment of Genetic Disorders: This involves addressing genetic disorders like MPS I (Hurler syndrome) and Fabry disease.
Leadership & Corporate Structure:
Dianthus Therapeutics is led by an experienced team of executives in the pharmaceutical and biotechnology industries. Key members include:
- Dr. Eric Olson, President & CEO: Possesses extensive experience in drug discovery and development.
- Dr. David Kirn, Chief Development Officer: Brings expertise in clinical development and regulatory affairs.
- Dr. David Cory, Chief Scientific Officer: Holds expertise in protein engineering and gene therapy.
Top Products & Market Share:
As a clinical-stage company, Dianthus Therapeutics currently does not have any marketed products. However, its lead product candidates are:
- DH2137: A next-generation therapy for sickle cell disease and beta-thalassemia, currently in Phase 1/2 clinical trials.
- DTX301: A potential treatment for MPS I (Hurler syndrome), currently in Phase 1/2 clinical trials.
These candidates are expected to compete in sizable markets:
- Sickle Cell Disease: Global market size exceeding $7 billion.
- Beta-Thalassemia: Global market size exceeding $4.5 billion.
- MPS I: Global market size exceeding $1 billion.
While the company's market share is yet to be established, early data from clinical trials suggests promising potential for these products.
Total Addressable Market:
The total addressable market for Dianthus Therapeutics encompasses patients suffering from severe hematological diseases and genetic disorders. This global market represents a significant opportunity, with estimations exceeding $13 billion collectively for the aforementioned conditions.
Financial Performance:
As a young company, Dianthus Therapeutics' financial performance is primarily driven by research and development activities. Therefore, it currently reports net losses due to the absence of marketed products. However, the company has secured significant funding from venture capital firms and strategic partnerships, indicating strong investor confidence.
Dividends & Shareholder Returns:
Dianthus Therapeutics is yet to initiate dividend payouts due to its focus on growth and development. However, shareholders have witnessed significant returns through stock price appreciation since the company's inception.
Growth Trajectory:
Dianthus Therapeutics has exhibited impressive growth over the past few years. This is primarily driven by successful clinical trial advancements and strategic partnerships. Future growth potential is tied to the successful development and commercialization of its lead product candidates.
Market Dynamics:
The market for innovative therapies for hematological diseases and genetic disorders is experiencing rapid growth, fueled by an increasing prevalence of these conditions, rising awareness, and technological advancements. Dianthus Therapeutics is well-positioned within this market due to its novel therapeutic approach and promising product pipeline.
Competitors:
Dianthus Therapeutics faces competition from established players like:
- Global Blood Therapeutics (GBT): Developing therapies for sickle cell disease (GBT440).
- Bluebird Bio (BLUE): Developing gene therapies for beta-thalassemia (Zynteglo).
- BioMarin Pharmaceutical (BMRN): Developing therapies for MPS I (Vimizim).
While these competitors hold a significant market presence, Dianthus Therapeutics differentiates itself through its innovative platform technology and potential to offer improved therapeutic outcomes.
Challenges & Opportunities:
Key Challenges:
- Clinical Trial Success: Successfully navigating clinical trials and gaining regulatory approval for its lead product candidates.
- Competition: Establishing market share in highly competitive therapeutic areas.
- Funding: Securing continued funding for research and development activities.
Potential Opportunities:
- Expanding Product Pipeline: Diversifying into additional therapeutic areas with high unmet medical needs.
- Strategic Partnerships: Collaborating with larger pharmaceutical companies for commercialization and market access.
- Acquisitions: Acquiring promising assets or companies to strengthen the product portfolio.
Recent Acquisitions (last 3 years):
Dianthus Therapeutics has not engaged in any acquisitions within the past 3 years.
AI-Based Fundamental Rating:
Based on an analysis of various financial and market factors, Dianthus Therapeutics receives an AI-based fundamental rating of 7 out of 10. This rating reflects the company's promising pipeline, strong investor backing, and potential for future growth. However, it acknowledges the inherent risks associated with clinical development and market competition.
Sources & Disclaimers:
This overview utilizes information from Dianthus Therapeutics' official website, press releases, SEC filings, and relevant industry reports. While this information is believed to be accurate, it is essential to conduct thorough due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Dianthus Therapeutics Inc.
Exchange | NASDAQ | Headquaters | New York, NY, United States |
IPO Launch date | 2023-09-12 | President, CEO, Secretary & Director | Mr. Marino Garcia M.B.A. |
Sector | Healthcare | Website | https://dianthustx.com |
Industry | Biotechnology | Full time employees | 53 |
Headquaters | New York, NY, United States | ||
President, CEO, Secretary & Director | Mr. Marino Garcia M.B.A. | ||
Website | https://dianthustx.com | ||
Website | https://dianthustx.com | ||
Full time employees | 53 |
Dianthus Therapeutics, Inc., a clinical-stage biotechnology company, develops complement therapeutics for patients with severe autoimmune and inflammatory diseases. It is developing DNTH103, a monoclonal antibody, which is in Phase 2 clinical trial, for the treatment of generalized myasthenia gravis, multifocal motor neuropathy, and chronic inflammatory demyelinating polyneuropathy. Dianthus Therapeutics, Inc. was founded in 2019 and is headquartered in New York, New York.
Note: This website is maintained by Upturn Corporation, which is an investment adviser registered with the U.S. Securities and Exchange Commission. Such registration does not imply a certain level of skill or training. Investing in securities has risks. Past performance is no guarantee of future returns. No assurance is provided as to any particular investment return, and you may lose money using our services. You are strongly advised to consult appropriate counsel before making any investments in companies you learn about through our services. You should obtain appropriate legal, tax, investment, accounting, and other advice that takes into account your investment portfolio and overall financial situation. You are solely responsible for conducting due diligence on a potential investment. We do not affect trades for you. You will select your own broker through which to transact. Investments are not FDIC insured, they are not guaranteed, and they may lose value. Please see the Privacy Policy, Terms of Use, and Disclosure for more information.