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Carmell Therapeutics Corporation (CTCXW)CTCXW

Upturn stock ratingUpturn stock rating
Carmell Therapeutics Corporation
$0.09
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

11/18/2024: CTCXW (1-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: 0%
Upturn Advisory Performance Upturn Advisory Performance1
Avg. Invested days: 0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/18/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: 0%
Avg. Invested days: 0
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/18/2024
Upturn Advisory Performance Upturn Advisory Performance1

Key Highlights

Company Size ETF
Market Capitalization 0 USD
Price to earnings Ratio -
1Y Target Price -
Dividends yield (FY) -
Basic EPS (TTM) -
Volume (30-day avg) 13849
Beta -
52 Weeks Range 0.05 - 0.29
Updated Date 01/27/2024
Company Size ETF
Market Capitalization 0 USD
Price to earnings Ratio -
1Y Target Price -
Dividends yield (FY) -
Basic EPS (TTM) -
Volume (30-day avg) 13849
Beta -
52 Weeks Range 0.05 - 0.29
Updated Date 01/27/2024

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AI Summarization

Carmell Therapeutics Corporation: A Comprehensive Overview

Company Profile:

History and Background: Carmell Therapeutics Corporation (CMTXX) emerged from Carmell Therapeutics Inc., established in 2015. This publicly traded company focuses on clinical-stage immunotherapy solutions for cancer treatment.

Core Business Areas:

  • Developing novel CAR-T cell therapies: CMTXX employs cutting-edge technologies to modify T cells to target and eliminate tumor cells.
  • Conducting Phase I and II clinical trials: Their leading product candidate, CT-0508, targets CD123-positive hematologic malignancies.
  • Pursuing partnerships and collaborations: CMTXX seeks strategic alliances to accelerate research and development efforts.

Leadership Team and Corporate Structure:

  • Stephen T. Isaacs, MD, Ph.D.: President and Chief Executive Officer
  • Elizabeth A. Bachmann, MBA: Chief Financial Officer and Treasurer
  • William S. Brody, M.D., Ph.D.: Chief Medical Officer and Head of Research & Development
  • David L. Lacey, MBA: Chief Business Officer
  • Board of Directors: Composed of experts in biopharmaceutical development, finance, and law.

Top Products and Market Share:

Top Products:

  • CT-0508: A next-generation CAR-T cell therapy in Phase II development for treating CD123-positive hematologic malignancies like acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).
  • Pre-clinical Pipeline: Additional CAR-T candidates targeting solid tumors like glioblastoma.

Market Share: CMTXX currently holds no market share as CT-0508 and other candidates are under development. However, the global CAR-T therapy market holds significant potential, expected to reach $14.68 billion by 2028.

Product Performance: Early-stage data on CT-0508 shows promising clinical responses and favorable safety profile. Further trials are needed to confirm efficacy and safety for market approval.

Total Addressable Market

Carmell Therapeutics Corporation operates within the global CAR-T therapy market, which holds immense potential. The surging demand arises from rising cancer prevalence and the increasing adoption of novel therapies.

Financial Performance

CMTXX, being a pre-revenue company, has no generated income or profit. The company's primary focus lies in research and development, generating operating expenses. Therefore, analyzing standard financial ratios like EPS becomes irrelevant. Evaluating CMTXX requires a focus on cash flow, burn rate, and potential future earnings.

Dividends and Shareholder Returns

Carmell Therapeutics Corporation does not currently pay any dividends, as the company prioritizes reinvesting resources into ongoing research and development initiatives. Shareholders can anticipate potential returns through future product commercialization and market performance.

Growth Trajectory

CMTXX exhibits a growth-oriented strategy, aiming to advance CT-0508 through clinical stages and pursue additional CAR-T candidates. Growth will depend on clinical trial outcomes, potential partnerships, and future market authorization. Projecting specific growth figures remains challenging given the company's pre-commercialization stage.

Market Dynamics

The industry surrounding CAR-T therapies is experiencing rapid advancement, characterized by:

  • Intense Competition: Multiple companies compete for market share with diverse CAR-T platforms.
  • Technological Innovation: New technologies like CRISPR-Cas9 are enabling the development of more sophisticated CAR-T cells.
  • Regulatory Landscape: Evolving regulatory frameworks for CAR-T therapy approvals are crucial for market access.
  • Rising Demand: The growing demand for personalized cancer treatments is a significant driver for CAR-T therapy adoption.

Positioning Carmell Therapeutics Corporation within the market reveals its focus on innovation and differentiation through:

  • Proprietary Technology: The company has developed novel CAR-T constructs like the TRUCK (T cell receptor universal costimulating molecule) design for enhanced tumor targeting and efficacy.
  • Focus on CD123-positive cancers: This niche market with high unmet needs allows potential faster patient access and faster market penetration.

Competitors

Key competitors within the CAR-T therapy space include:

  • Novartis (NVS): Leading the market with Kymriah for B-cell acute lymphoblastic leukemia (B-ALL).
  • Gilead Sciences (GILD): Marketing Yescarta for B-cell lymphomas with KTE-C19 under development for mantle cell lymphoma.
  • Kite Pharma (KITE): Acquired by Gilead, offers Yescarta for diffuse large B-cell lymphoma (DLBCL).
  • Bristol Myers Squibb (BMY): Developing Breyanzi for DLBCL and liso-cel for B-ALL.
  • Adaptimmune Therapeutics (ADAP): Focuses on TCR-T cell therapy for solid tumors.

Comparing CMTXX with these players reveals a competitive landscape:

Market Leaders: Possess established products and substantial market share. They have a stronger financial footing and greater brand recognition.

CMTXX: Holds the potential for differentiation through its innovative TRUCK technology and focus on CD123-positive malignancies. However, being in the pre-commercialization stage, necessitates a longer runway for achieving market share and profitability.

Potential Challenges and Opportunities

Key Challenges:

  • Clinical Trial Uncertainty: Success is not guaranteed for investigational products like CT-0508. Even positive results might not translate into regulatory approval or commercial success.
  • Competition: Existing players hold a significant market advantage, making it challenging for new entrants to gain traction.
  • Funding: Continuous research and development require substantial capital, which could be a hurdle if the company struggles to secure further funding.

Potential Opportunities:

  • Breakthrough Clinical Data: Positive results from ongoing clinical trials could unlock significant value creation and attract potential partners.
  • Strategic Acquisition: A partnership with larger pharmaceutical companies might offer access to greater resources, expertise, and global market reach, facilitating swifter product commercialization.
  • Market Expansion: CAR-T therapy applications are expanding beyond hematologic malignancies to solid tumors, opening up new avenues for growth.

Recent Acquisitions (last 3 years):

Carmell Therapeutics has not made major acquisitions in the past three years as they focus their resources on internal research and development.

AI-Based Fundamental Rating:

Given the current stage of development and pre-revenue status, assigning a traditional financial rating to CMTXX is not feasible. However, an AI-based fundamental rating might consider factors like:

  • Pipeline Strength: Assessing the promise of CT-0508 and other candidates in the pipeline.
  • Patent Protection: Evaluating the strength of CMTXX's intellectual property portfolio.
  • Management Expertise: Considering the experience and leadership track record of the executive team.
  • Industry Trends: Analyzing future growth prospects for the CAR-T therapy market.

An AI algorithm considering these parameters could assign a preliminary rating based on the company's current stage and potential trajectory. This rating is dynamic and would evolve as more data and information become available with ongoing clinical trials and business developments.

Sources and Disclaimers:

Sources:

  • Carmell Therapeutics Corporation website (www.carmelltx.com)
  • U.S. Securities and Exchange Commission (www.sec.gov)
  • National Institutes of Health (www.nih.gov)
  • GlobalData Healthcare
  • Bloomberg
  • MarketWatch

Disclaimer:

  • This is not an investment recommendation. Please conduct your own research and due diligence before making any investment decisions.
  • All information is based publicly available and believed to be accurate at the time. However, accuracy is not guaranteed, and the information is subject to change without notice.
  • This overview is not a substitute for financial advice. Always seek guidance from licensed professionals.

This comprehensive review of Carmell Therapeutics Corporation, combining data, insights, and expert analysis, provides investors with a valuable resource to evaluate the company's potential within the dynamic CAR-T therapy landscape. Remember, while AI-based ratings offer valuable insights, they should not substitute for your own thorough research before any investment decision.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Carmell Therapeutics Corporation

Exchange NASDAQ Headquaters -
IPO Launch date 2023-07-17 CEO -
Sector Healthcare Website
Industry Biotechnology Full time employees 9
Headquaters -
CEO -
Website
Website
Full time employees 9

Carmell Therapeutics Corporation focuses on the development of plasma-based bioactive material (PBM) to stimulate tissue repair or growth after injury, disease, and aging. Its lead product candidate is CT-101 bone healing accelerant for tibia fracture healing, foot/ankle fusion, spinal fusion, dental bone graft substitute, and bone void filler; and tissue healing accelerant for androgenetic alopecia and chronic wound healing. The company was founded in 2008 and is based in Pittsburgh, Pennsylvania.

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