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CARGO Therapeutics, Inc. Common Stock (CRGX)



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Upturn Advisory Summary
04/01/2025: CRGX (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -33.37% | Avg. Invested days 24 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 189.74M USD | Price to earnings Ratio - | 1Y Target Price 11.18 |
Price to earnings Ratio - | 1Y Target Price 11.18 | ||
Volume (30-day avg) 729885 | Beta - | 52 Weeks Range 3.00 - 25.45 | Updated Date 04/2/2025 |
52 Weeks Range 3.00 - 25.45 | Updated Date 04/2/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.72 |
Earnings Date
Report Date 2025-03-21 | When - | Estimate -0.9458 | Actual -0.95 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -27.01% | Return on Equity (TTM) -43.76% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -120542244 | Price to Sales(TTM) - |
Enterprise Value -120542244 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -12.16 | Shares Outstanding 46052400 | Shares Floating 27400238 |
Shares Outstanding 46052400 | Shares Floating 27400238 | ||
Percent Insiders 1.13 | Percent Institutions 122.65 |
Analyst Ratings
Rating 4.62 | Target Price 31.71 | Buy 3 | Strong Buy 5 |
Buy 3 | Strong Buy 5 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
CARGO Therapeutics, Inc. Common Stock
Company Overview
History and Background
CARGO Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing cell therapies for cancer. It was founded relatively recently, and its history involves preclinical development and clinical trials of its CAR-T cell therapy candidates.
Core Business Areas
- CAR-T Cell Therapy Development: Focuses on research, development, and clinical trials of CAR-T cell therapies for various cancers.
Leadership and Structure
CARGO Therapeutics, Inc. has a leadership team comprised of executives with experience in biotechnology, pharmaceuticals, and clinical development. The organizational structure typically includes research and development, clinical operations, manufacturing, and commercial functions.
Top Products and Market Share
Key Offerings
- CRG-808: CRG-808 is CARGO Therapeutics' lead clinical program, targeting relapsed/refractory multiple myeloma. No specific market share data is available at this stage as it is still in clinical development. Competitors include established CAR-T therapies such as Abecma (bb2121/idecabtagene vicleucel) from Bristol Myers Squibb and Carvykti (cilta-cel) from Legend Biotech/Janssen.
Market Dynamics
Industry Overview
The CAR-T cell therapy market is a rapidly growing segment of the oncology market, driven by the potential to provide durable remissions for patients with hematologic malignancies and solid tumors. However, high costs, manufacturing challenges, and potential toxicities remain significant barriers.
Positioning
CARGO Therapeutics, Inc. is positioned as a company focusing on improving CAR-T cell therapy through innovative cell engineering. Its competitive advantage would depend on demonstrating superior efficacy, safety, or manufacturing efficiency compared to existing CAR-T therapies.
Total Addressable Market (TAM)
The total addressable market for CAR-T cell therapies is estimated to reach billions of dollars annually. CARGO Therapeutics, Inc.'s position within this TAM will depend on the success of its clinical trials and subsequent commercialization.
Upturn SWOT Analysis
Strengths
- Novel CAR-T cell therapy platform
- Experienced leadership team
- Focus on specific cancer indications
- Strong intellectual property portfolio (potentially)
Weaknesses
- Early-stage clinical development
- High cash burn rate
- Dependence on clinical trial outcomes
- Limited commercial infrastructure
Opportunities
- Expanding CAR-T therapy to new cancer types
- Partnering with larger pharmaceutical companies
- Improving manufacturing processes to reduce costs
- Securing regulatory approvals for its therapies
Threats
- Competition from established CAR-T therapies
- Adverse clinical trial results
- Regulatory hurdles
- Pricing pressures
Competitors and Market Share
Key Competitors
- BMY
- GILD
- JNJ
- PFE
Competitive Landscape
CARGO Therapeutics, Inc. faces intense competition from established pharmaceutical companies with approved CAR-T therapies. Its success depends on demonstrating superior efficacy, safety, or cost-effectiveness.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth is limited due to the company's early stage.
Future Projections: Future growth is dependent on the success of clinical trials and regulatory approvals of its CAR-T cell therapies. Analyst estimates would be available from financial research firms.
Recent Initiatives: Recent initiatives would include initiation of new clinical trials, presentation of clinical data at scientific conferences, and potential partnerships with other companies.
Summary
CARGO Therapeutics is an early-stage biotech company focused on CAR-T cell therapy with the potential to disrupt the cancer treatment landscape. While its innovative approach is promising, it faces significant challenges in clinical development and competition from established players. Success depends on favorable clinical trial outcomes and effective commercialization strategies. The company needs to monitor its cash burn and secure additional funding to support its ongoing research and development programs.
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BMY

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GILD

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JNJ

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JNJ

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MRNA

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PFE

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Sources and Disclaimers
Data Sources:
- Company website, SEC filings, industry reports, analyst reports.
Disclaimers:
This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be based on individual circumstances and consultation with a qualified financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About CARGO Therapeutics, Inc. Common Stock
Exchange NASDAQ | Headquaters San Mateo, CA, United States | ||
IPO Launch date 2023-11-10 | Interim CEO, CFO, Secretary & COO Mr. Anup Radhakrishnan | ||
Sector Healthcare | Industry Biotechnology | Full time employees 167 | Website https://cargo-tx.com |
Full time employees 167 | Website https://cargo-tx.com |
CARGO Therapeutics, Inc., a clinical-stage biotechnology company, develops chimeric antigen receptor (CAR) T-cell therapies for cancer patients. The company's lead program is CRG-022, an autologous CD22 CAR T-cell product candidate designed to address resistance mechanisms by targeting CD22, an alternate tumor antigen that is expressed in B-cell malignancies. It also develops CRG-023, a tri-specific CAR T product candidate that targets tumor cells with three B-cell antigen targets. The company was formerly known as Syncopation Life Sciences, Inc. and changed its name to CARGO Therapeutics, Inc. in September 2022. CARGO Therapeutics, Inc. was incorporated in 2019 and is based in San Mateo, California.
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