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BioRestorative Therapies Inc (BRTX)



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Upturn Advisory Summary
03/27/2025: BRTX (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -44.05% | Avg. Invested days 34 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 12.53M USD | Price to earnings Ratio - | 1Y Target Price 13 |
Price to earnings Ratio - | 1Y Target Price 13 | ||
Volume (30-day avg) 728520 | Beta 63.74 | 52 Weeks Range 1.03 - 2.55 | Updated Date 03/30/2025 |
52 Weeks Range 1.03 - 2.55 | Updated Date 03/30/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.38 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date 2025-03-31 | When Before Market | Estimate -0.5533 | Actual -0.375 |
Profitability
Profit Margin - | Operating Margin (TTM) -6212.8% |
Management Effectiveness
Return on Assets (TTM) -58.03% | Return on Equity (TTM) -96.89% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -506412 | Price to Sales(TTM) 31.23 |
Enterprise Value -506412 | Price to Sales(TTM) 31.23 | ||
Enterprise Value to Revenue 0.68 | Enterprise Value to EBITDA 0.13 | Shares Outstanding 6919920 | Shares Floating 4322043 |
Shares Outstanding 6919920 | Shares Floating 4322043 | ||
Percent Insiders 27.7 | Percent Institutions 13.91 |
Analyst Ratings
Rating 4 | Target Price 13 | Buy 2 | Strong Buy - |
Buy 2 | Strong Buy - | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
BioRestorative Therapies Inc

Company Overview
History and Background
BioRestorative Therapies, Inc. was founded in 2007. It is a biotechnology company focused on stem cell therapies to address unmet needs in orthopedic and metabolic conditions. The company has evolved from initial research and development to clinical trials.
Core Business Areas
- Orthopedics: Development of stem cell therapies for disc degeneration and other orthopedic conditions, primarily through its disc/vertebral bone marrow stem cell platform (ThermoStemu00ae).
- Metabolic Diseases: Exploration of stem cell therapies for metabolic disorders like diabetes through its BRTX-100 product candidate.
Leadership and Structure
The leadership team includes Lance Alstodt as CEO, and the company is structured around clinical research and development, regulatory affairs, and manufacturing.
Top Products and Market Share
Key Offerings
- ThermoStemu00ae: An autologous stem cell therapy in clinical trials for the treatment of chronic lumbar disc disease (CLDD). Market share data is not publicly available as it is still in clinical stages. Competitors include companies developing similar regenerative medicine therapies for disc degeneration and spine conditions, such as Mesoblast, DiscGenics, and various companies in the biologics space.
- BRTX-100: A planned allogeneic stem cell therapy to be studied to treat metabolic disorders, initially targeting type 2 diabetes. Currently in pre-clinical stage and not yet generating revenue. Competitors will be established diabetes treatment providers, and companies developing novel metabolic therapies.
Market Dynamics
Industry Overview
The biotechnology industry is experiencing significant growth, particularly in regenerative medicine and stem cell therapies. There's a high demand for novel treatments for orthopedic and metabolic diseases.
Positioning
BioRestorative Therapies aims to be a leader in regenerative medicine for specific orthopedic and metabolic conditions. Its competitive advantage lies in its proprietary stem cell platform and focus on unmet medical needs.
Total Addressable Market (TAM)
The TAM for stem cell therapies in orthopedics and metabolic diseases is estimated to be billions of dollars. BioRestorative Therapies is positioned to capture a portion of this market pending successful clinical trials and regulatory approvals.
Upturn SWOT Analysis
Strengths
- Proprietary stem cell platform (ThermoStemu00ae)
- Focus on unmet medical needs
- Clinical-stage assets
- Experienced management team
Weaknesses
- Limited financial resources
- Dependence on clinical trial outcomes
- Regulatory hurdles
- Lack of approved products
Opportunities
- Positive clinical trial results
- Partnerships with larger pharmaceutical companies
- Expansion into new indications
- Increasing demand for regenerative medicine
Threats
- Clinical trial failures
- Regulatory setbacks
- Competition from larger companies
- Changes in healthcare policies
Competitors and Market Share
Key Competitors
- MESO
- BMDA
- ICEL
Competitive Landscape
BioRestorative Therapies is smaller than many of its competitors, with limited resources. However, it has a focused approach and proprietary technology.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth is minimal due to the developmental stage of the company.
Future Projections: Future growth depends on the successful completion of clinical trials, regulatory approvals, and commercialization of its therapies. Analyst estimates depend on clinical trial data.
Recent Initiatives: Recent initiatives include advancing the ThermoStemu00ae clinical trial and exploring partnerships for BRTX-100 development.
Summary
BioRestorative Therapies is a high-risk, high-reward biotechnology company focused on stem cell therapies. The company's success hinges on positive clinical trial outcomes and securing sufficient funding. While it has a promising technology platform, it faces significant competition and regulatory hurdles, so watch out for possible financial dilution to shareholder value.
Similar Companies
- MESO
- BMDA
- ICEL
Sources and Disclaimers
Data Sources:
- Company SEC Filings
- Company Website
- Industry Reports
- Financial News Outlets
Disclaimers:
The information provided is for informational purposes only and should not be considered financial advice. Investment decisions should be made based on thorough research and consultation with a financial professional. Market share data may be estimated based on available reports and public information.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About BioRestorative Therapies Inc
Exchange NASDAQ | Headquaters Melville, NY, United States | ||
IPO Launch date 2007-07-27 | Chairman of the Board, President & CEO Mr. Lance Alstodt | ||
Sector Healthcare | Industry Biotechnology | Full time employees 11 | Website https://www.biorestorative.com |
Full time employees 11 | Website https://www.biorestorative.com |
BioRestorative Therapies, Inc. develops therapeutic products and medical therapies using cell and tissue protocols primarily involving adult stem cells. The company develops programs relate to the treatment of disc/spine disease and metabolic disorders. Its products pipeline comprises BRTX-100, a lead cell therapy candidate formulated from autologous cultured mesenchymal stem cells collected from the patient's bone marrow, as well as used for the non-surgical treatment of painful lumbosacral disc disorders or as a complimentary therapeutic to a surgical procedure; and ThermoStem, a cell-based therapy candidate to target obesity and metabolic disorders using brown adipose derived stem cells to generate brown adipose tissue. The company also provides investigational curved needle device to deliver cells and/or other therapeutic products or material to the spine and discs, and other parts of the body. BioRestorative Therapies, Inc. has a research and development agreement with Rohto Pharmaceutical Co., Ltd.; a research agreement with Pfizer, Inc.; and a research collaboration agreement with the University of Pennsylvania. The company was formerly known as Stem Cell Assurance, Inc. and changed its name to BioRestorative Therapies, Inc. in August 2011. BioRestorative Therapies, Inc. is based in Melville, New York.
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