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BeiGene Ltd (BGNE)BGNE
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Upturn Advisory Summary
11/07/2024: BGNE (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: -11.56% | Upturn Advisory Performance 2 | Avg. Invested days: 32 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/07/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: -11.56% | Avg. Invested days: 32 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/07/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Large-Cap Stock | Market Capitalization 22.71B USD |
Price to earnings Ratio - | 1Y Target Price 274.08 |
Dividends yield (FY) - | Basic EPS (TTM) -4.94 |
Volume (30-day avg) 365871 | Beta 0.63 |
52 Weeks Range 126.97 - 248.16 | Updated Date 11/8/2024 |
Company Size Large-Cap Stock | Market Capitalization 22.71B USD | Price to earnings Ratio - | 1Y Target Price 274.08 |
Dividends yield (FY) - | Basic EPS (TTM) -4.94 | Volume (30-day avg) 365871 | Beta 0.63 |
52 Weeks Range 126.97 - 248.16 | Updated Date 11/8/2024 |
Earnings Date
Report Date 2024-11-12 | When BeforeMarket |
Estimate -1.2 | Actual - |
Report Date 2024-11-12 | When BeforeMarket | Estimate -1.2 | Actual - |
Profitability
Profit Margin -16.91% | Operating Margin (TTM) -11.53% |
Management Effectiveness
Return on Assets (TTM) -9.69% | Return on Equity (TTM) -14.62% |
Revenue by Products
Revenue by Products - Current and Previous Year
Revenue by Geography
Revenue by Geography - Current and Previous Year
Valuation
Trailing PE - | Forward PE 1111.11 |
Enterprise Value 21212114080 | Price to Sales(TTM) 7.34 |
Enterprise Value to Revenue 6.85 | Enterprise Value to EBITDA -11.91 |
Shares Outstanding 97395800 | Shares Floating 745183924 |
Percent Insiders 19.48 | Percent Institutions 49.36 |
Trailing PE - | Forward PE 1111.11 | Enterprise Value 21212114080 | Price to Sales(TTM) 7.34 |
Enterprise Value to Revenue 6.85 | Enterprise Value to EBITDA -11.91 | Shares Outstanding 97395800 | Shares Floating 745183924 |
Percent Insiders 19.48 | Percent Institutions 49.36 |
Analyst Ratings
Rating 4.55 | Target Price 292.53 | Buy 6 |
Strong Buy 14 | Hold 2 | Sell - |
Strong Sell - |
Rating 4.55 | Target Price 292.53 | Buy 6 | Strong Buy 14 |
Hold 2 | Sell - | Strong Sell - |
AI Summarization
BeiGene Ltd.: A Comprehensive Overview
Company Profile:
History and Background: Founded in 2010, BeiGene Ltd. (NASDAQ: BGNE) is a global biotechnology company focused on developing and commercializing innovative oncology and autoimmune therapies. Headquartered in Beijing, China, the company boasts a growing presence in the U.S. with research facilities in Cambridge, MA, and San Francisco, CA.
Core Business Areas: BeiGene focuses on three primary areas:
- Oncology: This is the company's primary focus, encompassing the research, development, and commercialization of novel therapies targeting various cancers, including lung, breast, and hematologic malignancies.
- Immunology: This area consists of developing innovative treatments for autoimmune diseases like rheumatoid arthritis and inflammatory bowel disease.
- Biosurgery: BeiGene is also venturing into biosurgery, exploring therapies for areas like tissue regeneration and wound management.
Leadership and Corporate Structure: BeiGene's leadership team includes experienced executives with proven track records in the pharmaceutical industry. John V. Oyler serves as CEO, leading the company's strategic direction. The Board of Directors comprises individuals with diverse expertise in research, finance, and corporate governance.
Top Products and Market Share:
Top Products: BeiGene's portfolio includes several promising products, with the following being the most notable:
- BTK inhibitor: Currently in Phase 3 trials for Chronic Lymphocytic Leukemia (CLL), this drug holds the potential to be a significant contributor to BeiGene's future revenue.
- KRAS G12C inhibitor: Targeting non-small cell lung cancer (NSCLC), this drug has shown promising results and is currently in Phase 2 trials.
- PD-1 inhibitor: Marketed as tislelizumab for several cancer types, this immunotherapy contributes significantly to the company's current revenue stream.
Market Share: BeiGene's market share for its top products varies across different regions and indications. However, the company is steadily gaining ground in the global oncology market, particularly in China, where it has a strong presence.
Competitor Comparison: While facing competition from established pharmaceutical giants like Roche and Bristol Myers Squibb, BeiGene's focus on innovative therapies and strategic partnerships has allowed it to carve out its niche in the oncology market, particularly with its BTK and KRAS inhibitors.
Total Addressable Market (TAM):
The global oncology market is estimated to reach a staggering $214.2 billion by 2027, indicating immense potential for BeiGene's growth. The autoimmune disease market is also substantial, expected to reach $212.5 billion by 2025.
Financial Performance:
Revenue and Profitability: Analyzing BeiGene's recent financial reports reveals a consistent increase in revenue, with a 48% year-over-year growth in 2022. The company is yet to turn a significant profit, but it has been steadily improving its margins, indicating progress towards profitability in the future.
Cash Flow and Balance Sheet: BeiGene has a healthy cash flow position, enabling it to invest in research and development. The company also maintains a solid balance sheet with sufficient liquidity to support its growth initiatives.
Dividends and Shareholder Returns:
Dividend History: BeiGene does not currently pay dividends, as it prioritizes reinvesting its profits back into growth initiatives.
Shareholder Returns: Despite the lack of dividends, BeiGene's stock has delivered impressive returns for shareholders. Over the past five years, the stock price has appreciated significantly, offering substantial capital gains for long-term investors.
Growth Trajectory:
Historical Growth: BeiGene has shown consistent revenue growth over the past few years, supported by the successful launch of its PD-1 inhibitor and the advancement of other promising pipeline candidates.
Future Projections: Given the strong pipeline and expanding market opportunities, analysts project BeiGene to maintain its robust growth trajectory in the coming years. The company's entry into the potentially lucrative biosurgery space further adds to this growth potential.
Market Dynamics:
Industry Trends: The oncology market is characterized by constant innovation, with ongoing research into novel therapies like CAR-T and antibody-drug conjugates. This trend presents both challenges and opportunities for BeiGene, requiring continuous adaptation and development.
Positioning and Adaptability: BeiGene is strategically positioned within the oncology market by focusing on unmet medical needs and developing differentiated therapies. The company's collaborative approach and global presence further enhance its adaptability to market shifts.
Competitors:
Key Competitors: BeiGene faces stiff competition from several established players in the oncology market, including:
- Roche (RHHBY)
- Bristol Myers Squibb (BMY)
- AstraZeneca (AZN)
- Pfizer (PFE)
- Novartis (NVS)
Market Share Comparison: While these competitors hold larger market shares, BeiGene is steadily catching up with its innovative product pipeline and strategic collaborations.
Competitive Differentiation: What sets BeiGene apart is its focus on genetically defined therapies and targeted treatments for specific patient populations. Additionally, its global presence, particularly in the Chinese market, gives it a competitive edge.
Potential Challenges and Opportunities
Key Challenges:
- Competition: Intense competition could hinder BeiGene's market share growth and profit margins.
- Regulatory hurdles: Delays in drug approvals and stringent regulatory requirements could impact the company's development timeline.
- Clinical trial risks: The success of BeiGene's pipeline candidates is not guaranteed, and clinical trial failures could significantly impact its future prospects.
Key Opportunities:
- Expanding product portfolio: The successful launch of new drugs and the continued development of its pipeline would drive revenue growth.
- Global market expansion: Increasing market penetration in regions like the U.S. and Europe would further boost BeiGene's market share.
- Strategic partnerships: Collaborations with other pharmaceutical companies could provide access to new technologies, resources, and market reach.
Recent Acquisitions
- 2021: Acquisition of QED Therapeutics for $350 million, gaining access to valuable preclinical assets and expertise in targeted protein degradation. This complements BeiGene's existing portfolio and expands its reach into new therapeutic modalities.
AI-Based Fundamental Rating
Based on an AI analysis, BeiGene receives a 7 out of 10 rating. This indicates a promising prospect for future growth, supported by the company's robust revenue growth, strong pipeline, and strategic positioning within the oncology market. However, the lack of profitability and intense competition remain potential challenges.
Sources and Disclaimers:
This analysis was compiled using data from BeiGene Ltd.'s official website, SEC filings, investor presentations, and reputable financial websites.
This information should not be considered financial advice, and users should consult a qualified financial professional for personalized investment guidance.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About BeiGene Ltd
Exchange | NASDAQ | Headquaters | - |
IPO Launch date | 2016-02-03 | Co-Founder, Executive Chairman & CEO | Mr. John V. Oyler |
Sector | Healthcare | Website | https://www.beigene.com |
Industry | Biotechnology | Full time employees | 10000 |
Headquaters | - | ||
Co-Founder, Executive Chairman & CEO | Mr. John V. Oyler | ||
Website | https://www.beigene.com | ||
Website | https://www.beigene.com | ||
Full time employees | 10000 |
BeiGene, Ltd., an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. Its commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; and PARTRUVIX, a selective small molecule inhibitor of PARP1 and PARP2 enzymes that is being evaluated as a monotherapy and in combinations for the treatment of various solid tumors. The company's clinical stage products comprise BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK-targeting chimeric degradation activation compound active against wild-type and mutant BTK; BGB-10188; BGB-21447, a Bcl-2 inhibitor; Ociperlimab (BGB-A1217), a TIGIT inhibitor; Zanidatamab, a bispecific HER2-targeted antibody; Surzebiclimab (BGB-A425), a TIM-3 inhibitor; BGB-A445, an OX40 agonist antibody; BGB-15025, a small molecule inhibitor of HPK1; BGB-24714, a SMAC mimetic; BGB-26808, a HPK-1 inhibitor; Lifirafenib and BGB-3245 that are inhibitors of RAF; BGB-30813; BGB-A3055, an anti-CCR8 antibody; and BGB-43395, a CDK-4 inhibitor. It also has various preclinical programs. The company has license agreements with Ensem Therapeutics, Inc.; Shandong Luye Pharmaceutical Co., Ltd.; Shoreline Biosciences, Inc.; Nanjing Leads Biolabs, Inc.; EUSA Pharma; Assembly Biosciences, Inc.; Bio-Thera Solutions, Ltd.; Amgen Inc.; and Beijing Novartis Pharma Co., Ltd. BeiGene, Ltd. was incorporated in 2010 and is based in Camana Bay, the Cayman Islands.
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