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Axogen Inc (AXGN)



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Upturn Advisory Summary
04/01/2025: AXGN (2-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit 7.92% | Avg. Invested days 30 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 820.36M USD | Price to earnings Ratio - | 1Y Target Price 25.71 |
Price to earnings Ratio - | 1Y Target Price 25.71 | ||
Volume (30-day avg) 644779 | Beta 1.02 | 52 Weeks Range 5.55 - 21.00 | Updated Date 04/1/2025 |
52 Weeks Range 5.55 - 21.00 | Updated Date 04/1/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.23 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -5.32% | Operating Margin (TTM) 4.08% |
Management Effectiveness
Return on Assets (TTM) -1.03% | Return on Equity (TTM) -9.99% |
Valuation
Trailing PE - | Forward PE 40.82 | Enterprise Value 849355892 | Price to Sales(TTM) 4.38 |
Enterprise Value 849355892 | Price to Sales(TTM) 4.38 | ||
Enterprise Value to Revenue 4.53 | Enterprise Value to EBITDA 139.72 | Shares Outstanding 44343800 | Shares Floating 38911671 |
Shares Outstanding 44343800 | Shares Floating 38911671 | ||
Percent Insiders 5.5 | Percent Institutions 81.99 |
Analyst Ratings
Rating 4.67 | Target Price 18.5 | Buy 2 | Strong Buy 4 |
Buy 2 | Strong Buy 4 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Axogen Inc

Company Overview
History and Background
Axogen Inc. was founded in 2002. It focuses on developing and marketing innovative surgical solutions for peripheral nerve repair. Initially, Axogen concentrated on nerve allografts and has since expanded into other nerve repair products. They have grown through internal development and acquisitions.
Core Business Areas
- Nerve Repair and Regeneration: This segment focuses on products and services for repairing damaged peripheral nerves, using nerve grafts and related technologies.
Leadership and Structure
Axogen's leadership team typically consists of a CEO, CFO, and other key executives managing various departments like R&D, Sales, and Marketing. The organizational structure is hierarchical, with teams reporting to department heads.
Top Products and Market Share
Key Offerings
- Avance Nerve Graft: A processed human nerve allograft used to bridge nerve gaps and facilitate nerve regeneration. Dominates the market in processed nerve allografts. Competitors include Stryker and Integra Lifesciences (although these are not direct substitutes.) Market share data is not always published, but this product generates the majority of Axogen revenue.
- AxoGuard Nerve Connector: A porcine submucosa extracellular matrix (ECM) coaptation aid designed to protect and support nerve repair. This is a smaller market with niche competitors. Data not available.
- Avive Soft Tissue Membrane: Used to minimize scar tissue formation around the nerve repair site and protect peripheral nerves during the healing process. Data not available.
Market Dynamics
Industry Overview
The peripheral nerve repair market is growing due to an aging population, increased trauma injuries, and advancements in surgical techniques. The market includes nerve grafts, nerve conduits, and nerve wraps.
Positioning
Axogen is a leader in the peripheral nerve repair market, particularly with its Avance Nerve Graft. Their competitive advantage lies in their allograft processing technology and focus on peripheral nerve repair.
Total Addressable Market (TAM)
Estimated TAM is around $2 billion globally. Axogen is positioned to capture a significant portion of this market with its nerve repair products. Market data varies by report and analyst estimates.
Upturn SWOT Analysis
Strengths
- Leading position in nerve allograft market
- Proprietary nerve allograft processing technology
- Established sales and distribution network
- Strong brand recognition within the nerve repair community
Weaknesses
- Reliance on a single primary product (Avance Nerve Graft)
- High cost of goods sold relative to revenue
- Potential ethical concerns regarding allograft usage
- Fluctuations in allograft supply
Opportunities
- Expansion into new geographical markets
- Development of new nerve repair products and technologies
- Increasing awareness of peripheral nerve injuries
- Potential acquisitions of complementary businesses
Threats
- Competition from alternative nerve repair methods (e.g., nerve conduits)
- Changes in reimbursement policies for nerve repair procedures
- Product liability claims related to nerve allografts
- Economic downturn affecting elective surgery volumes
Competitors and Market Share
Key Competitors
- STRY
- INTE
- BIIB
Competitive Landscape
Axogen's competitive advantage lies in its allograft processing technology. However, larger companies like Stryker and Integra have broader product portfolios and greater financial resources. BIIB, while operating in a similar field, is not a direct competitor but is in healthcare industry.
Major Acquisitions
NeuroMatrix, Inc.
- Year: 2012
- Acquisition Price (USD millions): 8
- Strategic Rationale: Expanded Axogen's product portfolio and capabilities in nerve repair.
Growth Trajectory and Initiatives
Historical Growth: Axogen experienced strong revenue growth in the past, driven by increased adoption of its Avance Nerve Graft. However, growth has slowed recently due to market factors and competition.
Future Projections: Analyst estimates project moderate revenue growth for Axogen, contingent upon successful product development and market penetration. [Provide numerical estimates if available]
Recent Initiatives: Recent initiatives include expanding into new surgical specialties and developing new nerve repair products.
Summary
Axogen is a leader in the niche market of peripheral nerve repair, particularly with its Avance Nerve Graft. They have proprietary technology, yet rely heavily on one product. The market is growing, but competition from larger medical device companies presents a challenge. They need to diversify and develop new avenues of growth.
Similar Companies
- STRY
- INTE
- BIIB
Sources and Disclaimers
Data Sources:
- Company filings (SEC)
- Analyst reports (FactSet, Bloomberg)
- Industry reports (Market Research Future, Medgadget)
- Axogen Inc. Investor Relations Website
Disclaimers:
This analysis is based on publicly available information and analyst estimates. It is not financial advice. Market data and market share is estimated. Actual figures may vary.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Axogen Inc
Exchange NASDAQ | Headquaters Alachua, FL, United States | ||
IPO Launch date 1990-03-27 | President, CEO & Director Mr. Michael D. Dale | ||
Sector Healthcare | Industry Medical Devices | Full time employees 451 | Website https://www.axogeninc.com |
Full time employees 451 | Website https://www.axogeninc.com |
Axogen, Inc., together with its subsidiaries, develops and commercializes technologies for peripheral nerve regeneration and repair worldwide. The company's products include Avance Nerve Graft, a biologically active off-the-shelf processed human nerve allograft for bridging severed peripheral nerves without the comorbidities associated with a second surgical site; AxoGuard Nerve Connector, a porcine submucosa extracellular matrix (ECM) coaptation aid for tensionless repair of severed peripheral nerves; AxoGuard Nerve Protector, a porcine submucosa ECM product that is used to wrap and protect damaged peripheral nerves, as well as reinforces the nerve reconstruction while preventing soft tissue attachments; and Axoguard HA+ Nerve Protector, a processed porcine submucosa ECM base layer with a hyaluronate-alginate gel coating designed to provide short- and long-term protection for peripheral nerve injuries. Its products also comprise Axoguard Nerve Cap, a porcine submucosa ECM product that is used to protect a peripheral nerve end, as well as separates the nerve from the surrounding environment to reduce the development of symptomatic or painful neuroma. The company provides its products to hospitals, surgery centers, and military hospitals, plastic reconstructive surgeons, orthopedic and plastic hand surgeons, and various oral and maxillofacial surgeons. Axogen, Inc. is headquartered in Alachua, Florida.
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