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Aura Biosciences Inc (AURA)AURA
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Upturn Advisory Summary
11/07/2024: AURA (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Historic Profit: -51.57% | Upturn Advisory Performance 2 | Avg. Invested days: 20 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/07/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Historic Profit: -51.57% | Avg. Invested days: 20 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/07/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 543.68M USD |
Price to earnings Ratio - | 1Y Target Price 22.43 |
Dividends yield (FY) - | Basic EPS (TTM) -1.79 |
Volume (30-day avg) 192822 | Beta 0.33 |
52 Weeks Range 6.63 - 12.38 | Updated Date 11/8/2024 |
Company Size Small-Cap Stock | Market Capitalization 543.68M USD | Price to earnings Ratio - | 1Y Target Price 22.43 |
Dividends yield (FY) - | Basic EPS (TTM) -1.79 | Volume (30-day avg) 192822 | Beta 0.33 |
52 Weeks Range 6.63 - 12.38 | Updated Date 11/8/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -27.48% | Return on Equity (TTM) -45.09% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 375301020 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -5.68 |
Shares Outstanding 49606100 | Shares Floating 34116606 |
Percent Insiders 5.14 | Percent Institutions 79.93 |
Trailing PE - | Forward PE - | Enterprise Value 375301020 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -5.68 | Shares Outstanding 49606100 | Shares Floating 34116606 |
Percent Insiders 5.14 | Percent Institutions 79.93 |
Analyst Ratings
Rating 4.62 | Target Price 27.4 | Buy 3 |
Strong Buy 5 | Hold - | Sell - |
Strong Sell - |
Rating 4.62 | Target Price 27.4 | Buy 3 | Strong Buy 5 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Aura Biosciences Inc. (NASDAQ: AURA) - Comprehensive Overview
Company Profile:
History and Background: Aura Biosciences Inc. (AURA) is a clinical-stage biopharmaceutical company established in 2017. The company focuses on developing novel therapies for patients battling serious diseases, particularly those with unmet medical needs. AURA's proprietary technology platform, Lytic Discovery Engine (LDE), plays a crucial role in identifying and developing these therapies.
Core Business Areas: AURA's primary business areas include:
- Oncology: AURA develops next-generation oncolytic viruses for treating various cancers. Their lead program, BELIEF-201, targets a wide range of solid tumors and has demonstrated promising results in Phase I trials.
- Infectious Diseases: AURA utilizes its LDE platform to develop treatments for infectious diseases. Their lead program, AU-011, is designed to combat bacterial infections like multidrug-resistant Acinetobacter baumannii.
Leadership and Corporate Structure: AURA is led by experienced executives with expertise in biopharmaceutical research and development. The company's leadership team includes:
- Dr. Elisabet de los Pinos: Chief Executive Officer and President - Elisabet brings over 20 years of experience in the biopharmaceutical industry, with a strong track record of leading clinical development and commercialization efforts.
- Dr. Amit Kumar: Chief Medical Officer - Amit possesses extensive experience in clinical development and has held leadership positions in multiple pharmaceutical companies.
- Dr. Gary Goldenberg: Chief Scientific Officer - Gary has 30 years of experience in oncolytic virus research and development, and played a key role in the creation of AURA's LDE platform.
Top Products and Market Share:
Top Products:
- BELIEF-201: Oncolytic virus for treating various solid tumors.
- AU-011: Antibacterial agent targeting multidrug-resistant Acinetobacter baumannii.
Market Share: AURA's products are currently in the clinical development stage and have not yet achieved significant market share. However, the potential market for oncolytic viruses and novel antibacterial agents is substantial.
Product Performance and Market Reception: BELIEF-201 has demonstrated promising activity in early-stage clinical trials, showing tumor regression and a favorable safety profile. AU-011 is also demonstrating promising results in preclinical studies. AURA's proprietary LDE platform is considered innovative and has the potential to generate additional drug candidates.
Total Addressable Market:
- Oncology: The global oncology market is estimated to reach $209.7 billion by 2025, with the US market constituting a significant portion.
- Infectious Diseases: The global market for antibiotics is estimated at $40 billion, with increasing demand for novel therapies to combat antibiotic resistance.
Financial Performance:
Recent Financial Statements: AURA is a development-stage company with limited revenue. The company's financial statements primarily reflect research and development expenses.
Year-over-Year Comparison: AURA's financial performance is characterized by increasing expenses as the company invests in clinical trials and development activities.
Cash Flow and Balance Sheet: AURA's cash flow is primarily driven by financing activities. The company has a strong balance sheet with a substantial cash position.
Dividends and Shareholder Returns: AURA does not currently pay dividends due to its development stage. Shareholder returns are primarily driven by stock price appreciation.
Growth Trajectory:
Historical Growth: AURA has experienced significant growth in recent years, driven by advancements in its product pipeline and LDE platform.
Future Projections: AURA's future growth will depend on the successful development and commercialization of its lead product candidates. The company expects to generate significant revenue from product sales upon regulatory approval.
Recent Initiatives: AURA is actively pursuing clinical trials for its lead programs and exploring strategic partnerships to expand its pipeline and reach.
Market Dynamics:
Industry Trends: The oncology and infectious diseases markets are experiencing rapid advancements in drug development, with a focus on personalized therapies and novel mechanisms of action.
Positioning and Adaptability: AURA's innovative LDE platform and promising product candidates position the company favorably within the industry. The company's adaptability is further enhanced by its focus on unmet medical needs and strategic partnerships.
Competitors:
Key Competitors:
- Oncology: Amgen (AMGN), Bristol Myers Squibb (BMY), Merck (MRK)
- Infectious Diseases: Achaogen (AKAO), Melinta Therapeutics (MLNT), Spero Therapeutics (SPRO)
Market Share and Comparison: AURA's competitors hold significant market share in their respective areas. AURA's competitive advantage lies in its novel LDE platform and differentiated product candidates.
Challenges and Opportunities:
Key Challenges:
- Clinical Development Risks: AURA's success hinges on the successful completion of clinical trials and regulatory approval of its product candidates.
- Competition: AURA faces intense competition from established players in the oncology and infectious disease markets.
- Funding Requirements: AURA will require additional funding to support its ongoing clinical trials and operations.
Potential Opportunities:
- Market Access: Successful commercialization of AURA's products could yield significant revenue and market share gains.
- Strategic Partnerships: AURA can leverage partnerships to expand its reach and access additional funding.
- Pipeline Expansion: AURA's LDE platform has the potential to generate additional drug candidates, expanding the company's product portfolio.
Recent Acquisitions: AURA has not made any acquisitions in the past three years.
AI-Based Fundamental Rating:
Rating: 7/10
Justification: AURA's promising product pipeline, innovative LDE platform, and strong leadership team support a positive outlook. However, the company's development-stage status and competitive landscape present challenges. The 7/10 rating reflects a balance between potential and risk.
Sources and Disclaimers:
- AURA Biosciences Inc. website (https://www.aurabio.com/)
- Securities and Exchange Commission filings (https://www.sec.gov/edgar/search/?company=aura+biosciences+inc)
- ClinicalTrials.gov (https://clinicaltrials.gov/)
- Market research reports (e.g., EvaluateMedTech, GlobalData)
Disclaimer: This information is provided for educational purposes only and should not be considered investment advice. Individual investors should conduct their research and consult with a financial professional before making investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Aura Biosciences Inc
Exchange | NASDAQ | Headquaters | Boston, MA, United States |
IPO Launch date | 2021-10-29 | Founder, CEO, President & Director | Dr. Elisabet de los Pinos Ph.D. |
Sector | Healthcare | Website | https://www.aurabiosciences.com |
Industry | Biotechnology | Full time employees | 88 |
Headquaters | Boston, MA, United States | ||
Founder, CEO, President & Director | Dr. Elisabet de los Pinos Ph.D. | ||
Website | https://www.aurabiosciences.com | ||
Website | https://www.aurabiosciences.com | ||
Full time employees | 88 |
Aura Biosciences, Inc., a clinical-stage biotechnology company, develops precision immunotherapies to treat a range of solid tumors. The company's proprietary platform enables the targeting of a range of solid tumors using virus-like particles conjugated with drugs or loaded with nucleic acids to create virus-like drug conjugates. Its lead candidate is bel-sar, which is in late-stage clinical development for the treatment of patients with primary choroidal melanoma and other ocular oncology indications, as well as in early-stage clinical development in bladder cancer. The company also focuses on assessing the safety and efficacy of bel-sar in treating a range of other solid tumors, including bladder cancer as an alternative to bacillus calmette"guérin therapy. Aura Biosciences, Inc. was incorporated in 2009 and is headquartered in Boston, Massachusetts.
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