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Ardelyx Inc (ARDX)ARDX
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Upturn Advisory Summary
09/18/2024: ARDX (5-star) is a WEAK-BUY. BUY since 16 days. Profits (-5.14%). Updated daily EoD!
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: WEAK BUY |
Profit: 251.59% | Upturn Advisory Performance 3 | Avg. Invested days: 36 |
Profits based on simulation | Stock Returns Performance 5 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: WEAK BUY |
Profit: 251.59% | Avg. Invested days: 36 |
Upturn Star Rating | Stock Returns Performance 5 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.45B USD |
Price to earnings Ratio - | 1Y Target Price 11.65 |
Dividends yield (FY) - | Basic EPS (TTM) -0.27 |
Volume (30-day avg) 2702585 | Beta 0.89 |
52 Weeks Range 3.16 - 10.13 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 1.45B USD | Price to earnings Ratio - | 1Y Target Price 11.65 |
Dividends yield (FY) - | Basic EPS (TTM) -0.27 | Volume (30-day avg) 2702585 | Beta 0.89 |
52 Weeks Range 3.16 - 10.13 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -31.02% | Operating Margin (TTM) -18.62% |
Management Effectiveness
Return on Assets (TTM) -13.27% | Return on Equity (TTM) -48.23% |
Revenue by Products
Revenue by Products - Current and Previous Year
Revenue by Geography
Revenue by Geography - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 1366817325 | Price to Sales(TTM) 6.89 |
Enterprise Value to Revenue 6.51 | Enterprise Value to EBITDA -27.36 |
Shares Outstanding 235428000 | Shares Floating 229890912 |
Percent Insiders 1.62 | Percent Institutions 61.83 |
Trailing PE - | Forward PE - | Enterprise Value 1366817325 | Price to Sales(TTM) 6.89 |
Enterprise Value to Revenue 6.51 | Enterprise Value to EBITDA -27.36 | Shares Outstanding 235428000 | Shares Floating 229890912 |
Percent Insiders 1.62 | Percent Institutions 61.83 |
Analyst Ratings
Rating 4.7 | Target Price 9.81 | Buy 1 |
Strong Buy 8 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.7 | Target Price 9.81 | Buy 1 | Strong Buy 8 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Ardelyx Inc. Stock Overview
Company Profile
History and Background:
Ardelyx Inc. is a clinical-stage biopharmaceutical company established in 1997. Its headquarters are in Waltham, Massachusetts. The company focuses on developing and commercializing innovative therapies for patients with serious gastrointestinal and cardiorenal diseases.
Core Business Areas:
Ardelyx's core business areas include:
- Gastrointestinal diseases: Tenapanor is their lead product candidate, targeting hyperphosphatemia in patients with chronic kidney disease (CKD) and elevated serum phosphorus levels.
- Cardiorenal diseases: RDX013 is a potassium-binding agent for the potential treatment of high potassium levels in patients with CKD.
Leadership and Corporate Structure:
As of November 2023, the leadership team comprises:
- Mike Raab, President, Chief Executive Officer, and Chairman
- John Orwin, Chief Medical Officer
- John McVeigh, Chief Financial Officer and Treasurer
- Christopher A. White, Chief Operating Officer and Head of Ardelyx Therapeutics
Top Products and Market Share:
- Tenapanor: This drug is approved in the US for the treatment of hyperphosphatemia in adult patients with CKD on dialysis. It is not yet commercially available, awaiting FDA approval for CKD patients not on dialysis.
- RDX013: This drug is in Phase 3 development for the treatment of high potassium levels in CKD patients. It faces competition from existing treatments like sodium zirconium cyclosilicate (Lokelma).
Market Share:
- Tenapanor: Currently holds no market share as it is not commercially available except for CKD patients on dialysis.
- RDX013: Holds no market share as it is still in Phase 3 development.
Total Addressable Market:
- Hyperphosphatemia in CKD: Estimated at 376,000 patients in the US and 1.8 million patients globally.
- High potassium levels in CKD: Estimated at 200,000 patients in the US and 1 million patients globally.
Financial Performance:
- Revenue: Generated $1.5 million in the first half of 2023, primarily from Tenapanor sales to CKD patients on dialysis.
- Net Income: Reported a net loss of $49.2 million in the first half of 2023.
- Profit Margins: Gross margin of 38% in the first half of 2023.
- Earnings per Share (EPS): -$0.42 in the first half of 2023.
Dividends and Shareholder Returns:
- Dividend History: Ardelyx does not currently pay dividends.
- Shareholder Returns: Share price has declined significantly in 2023.
Growth Trajectory:
- Historical Growth: Revenue growth has been limited due to Tenapanor's restricted market access.
- Future Growth: Potential for significant growth upon wider Tenapanor approval and RDX013 commercialization.
Market Dynamics:
- Industry: The CKD market is expected to grow significantly due to the rising prevalence of diabetes and hypertension.
- Demand-Supply: Supply of therapies for hyperphosphatemia and high potassium levels is expected to remain stable, with potential for increased competition.
- Technological Advancements: Ardelyx utilizes proprietary technology platforms for drug development.
Competitive Landscape:
- Key Competitors:
- Keryx Biopharmaceuticals (KERX)
- Vifor Pharma (VPHM.VX)
- Fresenius Medical Care (FME.DE)
- Competitive Advantages: Tenapanor's unique mechanism of action and potential for once-daily dosing.
- Competitive Disadvantages: Limited market access for Tenapanor and late-stage development of RDX013.
Potential Challenges and Opportunities:
- Challenges: Regulatory hurdles, competition, and market access limitations.
- Opportunities: Expansion of Tenapanor's label, successful development of RDX013, and potential partnerships.
Recent Acquisitions:
Ardelyx has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating:
Based on available data, Ardelyx receives a rating of 5 out of 10. This rating considers the company's early-stage commercialization, limited revenue, and dependence on Tenapanor's success. While the potential market for their products is substantial, the company faces challenges in gaining market share and achieving profitability.
Sources:
- Ardelyx Inc. website: https://www.ardelyx.com/
- Yahoo Finance: https://finance.yahoo.com/quote/ARDX/
- SEC filings: https://www.sec.gov/edgar/search/
- Market research reports
Disclaimer: This information is for informational purposes only and should not be considered financial advice. Please consult a financial professional before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Ardelyx Inc
Exchange | NASDAQ | Headquaters | Waltham, MA, United States |
IPO Launch date | 2014-06-19 | President, CEO & Director | Mr. Michael G. Raab |
Sector | Healthcare | Website | https://www.ardelyx.com |
Industry | Biotechnology | Full time employees | 267 |
Headquaters | Waltham, MA, United States | ||
President, CEO & Director | Mr. Michael G. Raab | ||
Website | https://www.ardelyx.com | ||
Website | https://www.ardelyx.com | ||
Full time employees | 267 |
Ardelyx, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines to treat gastrointestinal and cardiorenal therapeutic areas in the United States and internationally. The company's lead product candidate is tenapanor for the treatment of patients with irritable bowel syndrome with constipation. It also develops XPHOZAH, which is in Phase III clinical trial to reduce serum phosphorus in adults with chronic kidney disease (CKD)on dialysis, or hyperphosphatemia; RDX013, a potassium secretagogue, for the treatment of elevated serum potassium, or hyperkalemia, a problem among patients with kidney and/or heart failure; and RDX020, for adult patients with metabolic acidosis, a serious electrolyte disorder. The company has agreements with Kyowa Kirin, Fosun Pharmaceutical Industrial Development Co. Ltd., and Knight Therapeutics, Inc. for the development and commercialization of tenapanor in their respective territories. The company was formerly known as Nteryx, Inc. and changed its name to Ardelyx, Inc. in June 2008. Ardelyx, Inc. was incorporated in 2007 and is headquartered in Waltham, Massachusetts.
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