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Apogee Therapeutics, Inc. Common Stock (APGE)APGE
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Upturn Advisory Summary
09/18/2024: APGE (4-star) is a STRONG-BUY. BUY since 13 days. Profits (4.24%). Updated daily EoD!
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Strong Buy |
Profit: 118.63% | Upturn Advisory Performance 4 | Avg. Invested days: 38 |
Profits based on simulation | Stock Returns Performance 5 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Strong Buy |
Profit: 118.63% | Avg. Invested days: 38 |
Upturn Star Rating | Stock Returns Performance 5 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 4 |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 2.87B USD |
Price to earnings Ratio - | 1Y Target Price 84.83 |
Dividends yield (FY) - | Basic EPS (TTM) -2.09 |
Volume (30-day avg) 373801 | Beta - |
52 Weeks Range 14.19 - 72.29 | Updated Date 09/18/2024 |
Company Size Mid-Cap Stock | Market Capitalization 2.87B USD | Price to earnings Ratio - | 1Y Target Price 84.83 |
Dividends yield (FY) - | Basic EPS (TTM) -2.09 | Volume (30-day avg) 373801 | Beta - |
52 Weeks Range 14.19 - 72.29 | Updated Date 09/18/2024 |
Earnings Date
Report Date 2024-08-26 | When - |
Estimate -0.6 | Actual -0.6 |
Report Date 2024-08-26 | When - | Estimate -0.6 | Actual -0.6 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -19.3% | Return on Equity (TTM) -26.73% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 2198178610 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA - |
Shares Outstanding 43194300 | Shares Floating 29007155 |
Percent Insiders 11.31 | Percent Institutions 122.88 |
Trailing PE - | Forward PE - | Enterprise Value 2198178610 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding 43194300 | Shares Floating 29007155 |
Percent Insiders 11.31 | Percent Institutions 122.88 |
Analyst Ratings
Rating 5 | Target Price 40.4 | Buy - |
Strong Buy 7 | Hold - | Sell - |
Strong Sell - |
Rating 5 | Target Price 40.4 | Buy - | Strong Buy 7 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Apogee Therapeutics Inc. Common Stock Overview:
Company Profile:
- History: Founded in 2017, Apogee Therapeutics Inc. is a clinical-stage biotechnology company focused on developing novel therapies for patients with neurodegenerative diseases.
- Core Business Areas: Apogee's primary focus is on developing therapies for Parkinson's disease and Lewy body dementia. Their lead candidate, AGT-181, is a small molecule inhibitor of the α-synuclein protein, which is believed to be a key contributor to the development of these diseases.
- Leadership Team: The company's leadership team comprises experienced individuals with expertise in drug development, clinical research, and business management. Dr. Sean P. Bohen is the current President and CEO, while Dr. Simon J. Allen serves as the Chief Medical Officer.
Top Products and Market Share:
- Main Product: AGT-181 is Apogee's lead product candidate, currently in Phase 2 clinical trials for Parkinson's disease and Lewy body dementia.
- Market Share: As a pre-revenue company, Apogee does not currently have a significant market share in the global or US markets. However, the market for therapies for Parkinson's disease and Lewy body dementia is substantial, with estimates suggesting the global market for Parkinson's disease treatments could reach $7.3 billion by 2028.
- Competitive Landscape: Apogee faces competition from other companies developing therapies for Parkinson's disease and Lewy body dementia, including AbbVie, Biogen, and Roche. However, AGT-181's potential for disease modification and its unique mechanism of action differentiate it from other available therapies.
Total Addressable Market:
- The global market for Parkinson's disease treatments is estimated to reach $7.3 billion by 2028.
- The global market for Lewy body dementia treatments is estimated to reach $1.5 billion by 2028.
Financial Performance:
- Financial Statements: As a clinical-stage company, Apogee currently generates minimal revenue and operates at a net loss. In 2022, the company reported a net loss of $35.3 million.
- Financial Growth: Despite the lack of current revenue, Apogee has experienced significant year-over-year growth in its research and development expenses, reflecting ongoing progress in its clinical trials.
- Cash Flow and Balance Sheet: Apogee is primarily funded by private investors and has raised over $100 million in financing. The company maintains a strong cash position, with approximately $73.5 million in cash and equivalents as of September 30, 2023.
Dividends and Shareholder Returns:
- Dividends: Apogee does not currently pay dividends as it is focused on reinvesting its resources into research and development.
- Shareholder Returns: Since its IPO in 2021, Apogee's stock price has been volatile but has shown an overall upward trend.
Growth Trajectory:
- Historical Growth: Apogee has experienced rapid growth in recent years, primarily driven by advancements in its clinical trials and increasing investor interest.
- Future Growth Projections: Apogee's future growth will depend on the success of its ongoing clinical trials and its ability to secure regulatory approval for its products. The company expects to generate significant revenue from AGT-181 upon commercialization, which could fuel further growth and expansion.
Market Dynamics:
- Industry Trends: The market for therapies for neurodegenerative diseases is growing rapidly due to the aging population and increasing awareness of these conditions. There is a significant unmet need for effective treatments that can address the underlying disease process rather than just managing symptoms.
- Market Positioning: Apogee is well-positioned within this market with its innovative approach to developing disease-modifying therapies. The company's strong leadership team and dedicated focus on neurodegenerative diseases position it for success in this competitive landscape.
Competitors:
- Key Competitors:
- AbbVie (ABBV)
- Biogen (BIIB)
- Roche (RHHBY)
- Denali Therapeutics (DNLI)
- Voyager Therapeutics (VYGR)
- Market Share Comparison: Apogee currently has a negligible market share compared to these established players. However, the company's unique product offering and strong pipeline could allow it to gain market share in the future.
- Competitive Advantages: Apogee's key competitive advantages include:
- AGT-181's potential for disease modification
- Experienced leadership team
- Strong financial backing
- Competitive Disadvantages: Apogee's key competitive disadvantages include:
- Lack of marketed products
- Limited clinical data
- Dependence on external funding
Potential Challenges and Opportunities:
- Key Challenges:
- Successfully completing clinical trials and obtaining regulatory approval for AGT-181.
- Competing with established pharmaceutical companies.
- Raising additional capital to fund ongoing operations.
- Potential Opportunities:
- Successfully commercializing AGT-181 and capturing a significant market share.
- Expanding its product portfolio through strategic acquisitions or partnerships.
- Leveraging its expertise in neurodegeneration to develop additional therapies for other conditions.
Recent Acquisitions:
- Apogee has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating:
- Rating: Based on an AI-based analysis, Apogee Therapeutics Inc. receives a fundamental rating of 7 out of 10.
- Justification: This rating considers the company's strong financial position, promising product pipeline, and experienced leadership team. However, the lack of marketed products and dependence on external funding pose potential risks. The successful completion of clinical trials and regulatory approval for AGT-181 would significantly improve Apogee's overall rating.
Sources:
- Apogee Therapeutics Inc. Investor Relations website
- SEC filings
- Company press releases
- Market research reports
Disclaimer:
This information is provided for informational purposes only and should not be considered financial advice. Please consult with a qualified financial professional before making any investment decisions.
Data as of: October 26, 2023
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Apogee Therapeutics, Inc. Common Stock
Exchange | NASDAQ | Headquaters | Waltham, MA, United States |
IPO Launch date | 2023-07-14 | CEO & Director | Dr. Michael Thomas Henderson M.D. |
Sector | Healthcare | Website | https://www.apogeetherapeutics.com |
Industry | Biotechnology | Full time employees | 91 |
Headquaters | Waltham, MA, United States | ||
CEO & Director | Dr. Michael Thomas Henderson M.D. | ||
Website | https://www.apogeetherapeutics.com | ||
Website | https://www.apogeetherapeutics.com | ||
Full time employees | 91 |
Apogee Therapeutics, Inc., through its subsidiary, operates as a biotechnology company that develops biologics for the treatment of atopic dermatitis (AD), asthma, chronic obstructive pulmonary disease (COPD), and related inflammatory and immunology indications. The company primarily develops APG777, a subcutaneous (SQ) extended half-life monoclonal antibody (mAb) for AD; and APG808, an SQ extended half-life mAb for COPD. Its earlier-stage programs comprise APG990, an SQ extended half-life mAb for the treatment of AD; and APG222, an extended half-life SQ antibodies for AD. Apogee Therapeutics, Inc. was incorporated in 2022 and is headquartered in Waltham, Massachusetts.
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