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ANVS logo ANVS
Upturn stock ratingUpturn stock rating
ANVS logo

Annovis Bio Inc (ANVS)

Upturn stock ratingUpturn stock rating
$1.49
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

04/01/2025: ANVS (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type Stock
Historic Profit -93.24%
Avg. Invested days 31
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 29.03M USD
Price to earnings Ratio -
1Y Target Price 31.2
Price to earnings Ratio -
1Y Target Price 31.2
Volume (30-day avg) 371620
Beta 1.65
52 Weeks Range 1.43 - 20.00
Updated Date 04/1/2025
52 Weeks Range 1.43 - 20.00
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.31

Earnings Date

Report Date 2025-03-27
When After Market
Estimate -0.2
Actual -0.43

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -138.27%
Return on Equity (TTM) -3159.09%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 18482568
Price to Sales(TTM) -
Enterprise Value 18482568
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -3.57
Shares Outstanding 19486200
Shares Floating 15671217
Shares Outstanding 19486200
Shares Floating 15671217
Percent Insiders 14.45
Percent Institutions 13.25

Analyst Ratings

Rating 4.33
Target Price 34.8
Buy 2
Strong Buy 3
Buy 2
Strong Buy 3
Hold 1
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Annovis Bio Inc

stock logo

Company Overview

overview logo History and Background

Annovis Bio, Inc. is a clinical-stage drug platform company addressing neurodegenerative diseases. Founded in 2008, it focuses on developing therapies for Alzheimer's and Parkinson's diseases.

business area logo Core Business Areas

  • Drug Development: Developing and commercializing therapeutics targeting neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

leadership logo Leadership and Structure

Dr. Maria L. Maccecchini is the CEO. The company has a board of directors overseeing its operations and strategy.

Top Products and Market Share

overview logo Key Offerings

  • Posiphen: Posiphen is an oral drug candidate targeting multiple toxic proteins implicated in neurodegenerative diseases. It's in clinical trials, but currently has no market share. Competitors include companies developing other Alzheimer's and Parkinson's treatments, such as Eli Lilly (LLY) and Biogen (BIIB).

Market Dynamics

industry overview logo Industry Overview

The neurodegenerative disease market is large and growing, with significant unmet medical needs, particularly for Alzheimer's and Parkinson's diseases.

Positioning

Annovis Bio aims to address the root causes of neurodegeneration, potentially offering a disease-modifying approach. This differentiates them from companies focused on symptomatic treatments.

Total Addressable Market (TAM)

The Alzheimer's disease market is estimated to exceed $10 billion globally. Annovis Bio's position depends on clinical trial success and regulatory approval.

Upturn SWOT Analysis

Strengths

  • Novel drug platform targeting multiple toxic proteins
  • Potential disease-modifying approach
  • Experienced management team

Weaknesses

  • Limited financial resources
  • Reliance on clinical trial success
  • No approved products

Opportunities

  • Positive clinical trial results
  • Partnerships with larger pharmaceutical companies
  • Expansion into new neurodegenerative indications

Threats

  • Clinical trial failures
  • Competition from established pharmaceutical companies
  • Regulatory hurdles

Competitors and Market Share

competitor logo Key Competitors

  • LLY
  • BIIB
  • ABBV
  • SNY
  • MRK

Competitive Landscape

Annovis Bio faces stiff competition from larger, established pharmaceutical companies with greater resources. However, its novel approach could provide a competitive edge.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Annovis Bio's historical growth is characterized by preclinical and clinical development of its drug candidates.

Future Projections: Future growth depends on clinical trial outcomes and regulatory approvals, making projections speculative.

Recent Initiatives: Recent initiatives include ongoing clinical trials for Posiphen in Alzheimer's and Parkinson's diseases.

Summary

Annovis Bio is a clinical-stage company with a novel approach to treating neurodegenerative diseases. Its strength lies in its unique drug platform, but it faces significant risks due to its reliance on clinical trial success and limited resources. Positive clinical trial results are crucial for its future prospects. The company needs to secure partnerships to bolster its financial stability and expand its development efforts.

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Sources and Disclaimers

Data Sources:

  • Company filings
  • Analyst reports
  • Industry news

Disclaimers:

This analysis is for informational purposes only and does not constitute investment advice. Financial data may be outdated and subject to change.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Annovis Bio Inc

Exchange NYSE
Headquaters Malvern, PA, United States
IPO Launch date 2010-02-12
Founder, CEO, President, Interim Principal Financial Officer & Executive Director Dr. Maria L. Maccecchini Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 8
Full time employees 8

Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration. The company's lead product candidate is Buntanetap, which has completed three Phase 1/2 clinical trials for the treatment of Alzheimer's disease (AD), Parkinson's disease, and other chronic neurodegenerative diseases. It is also developing ANVS405, which is in Phase 2 and Phase 3 efficacy studies, an intravenous drug for protecting the brain after traumatic brain injury and/or stroke; and ANVS301, which is in Phase I clinical trials, an orally administered drug to increase cognitive capability in later stages of AD and dementia. The company was incorporated in 2008 and is based in Malvern, Pennsylvania.

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