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Annovis Bio Inc (ANVS)
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Upturn Advisory Summary
12/16/2024: ANVS (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: -93.24% | Upturn Advisory Performance 2 | Avg. Invested days: 31 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 12/16/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: -93.24% | Avg. Invested days: 31 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 12/16/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 69.12M USD |
Price to earnings Ratio - | 1Y Target Price 34.8 |
Dividends yield (FY) - | Basic EPS (TTM) -4.22 |
Volume (30-day avg) 268851 | Beta 1.7 |
52 Weeks Range 4.21 - 21.50 | Updated Date 12/24/2024 |
Company Size Small-Cap Stock | Market Capitalization 69.12M USD | Price to earnings Ratio - | 1Y Target Price 34.8 |
Dividends yield (FY) - | Basic EPS (TTM) -4.22 | Volume (30-day avg) 268851 | Beta 1.7 |
52 Weeks Range 4.21 - 21.50 | Updated Date 12/24/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -154.58% | Return on Equity (TTM) -596.7% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 48899069 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.57 |
Shares Outstanding 13797200 | Shares Floating 10822005 |
Percent Insiders 20.4 | Percent Institutions 8.83 |
Trailing PE - | Forward PE - | Enterprise Value 48899069 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.57 | Shares Outstanding 13797200 | Shares Floating 10822005 |
Percent Insiders 20.4 | Percent Institutions 8.83 |
Analyst Ratings
Rating 4.33 | Target Price 46 | Buy 2 |
Strong Buy 3 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.33 | Target Price 46 | Buy 2 | Strong Buy 3 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Annovis Bio Inc. (ANVS) Stock Overview
Company Profile:
History and Background:
- Founded in 2011, Annovis Bio Inc. (ANVS) is a clinical-stage biopharmaceutical company focused on developing treatments for neurological disorders.
- ANVS focuses on developing drug candidates for Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases.
- Headquartered in Berwyn, Pennsylvania, ANVS has a research and development facility in the Netherlands.
Core Business Areas:
- ANVS's core business area is the development and commercialization of drug candidates for neurodegenerative diseases.
- The company has two lead drug candidates in its pipeline: ANVS401 for Alzheimer's disease and ANVS403 for Parkinson's disease.
- ANVS is also developing other drug candidates for other neurodegenerative diseases, including Dravet syndrome.
Leadership and Corporate Structure:
- Maria Maccecchini, Ph.D., is the President and CEO of ANVS.
- The company's leadership team also includes Dr. Nir Menachemi, Chief Medical Officer, and Dr. Greg Mayes, Chief Scientific Officer.
- ANVS operates a Board of Directors led by Chairman William Gozzi.
Top Products and Market Share:
Top Products:
- ANVS401 is a drug candidate for Alzheimer's disease that is currently in Phase 2b clinical trials.
- ANVS403 is a drug candidate for Parkinson's disease that is currently in Phase 2a clinical trials.
- ANVS is also developing other drug candidates for other neurodegenerative diseases, including Dravet syndrome.
Market Share:
- As of November 2023, ANVS does not have any marketed products.
- Therefore, it does not have any market share in the global or US markets.
Product Performance and Market Reception:
- ANVS401 has shown promising results in Phase 2a clinical trials for Alzheimer's disease.
- The company is currently conducting Phase 2b clinical trials for ANVS401.
- ANVS403 is in Phase 2a clinical trials for Parkinson's disease.
- Initial results have been positive, with the drug candidate showing potential for improving motor function in patients with Parkinson's disease.
- The market reception to ANVS's drug candidates has been positive, with investors optimistic about the company's potential to develop successful treatments for neurodegenerative diseases.
Total Addressable Market:
- The global market for Alzheimer's disease treatments is estimated to be worth $13.5 billion in 2023.
- The market is expected to grow to $16.5 billion by 2028.
- The global market for Parkinson's disease treatments is estimated to be worth $4.5 billion in 2023.
- The market is expected to grow to $5.5 billion by 2028.
Financial Performance:
Recent Financial Statements:
- As of November 2023, ANVS does not have any marketed products.
- Therefore, the company does not generate any revenue.
- ANVS is currently in the development stage and is incurring significant losses.
- In 2022, the company reported a net loss of $47.4 million.
Year-over-Year Performance:
- ANVS's net loss has been increasing in recent years.
- In 2021, the company reported a net loss of $34.5 million.
- The company's increasing losses are due to the high costs associated with drug development.
Cash Flow and Balance Sheet:
- ANVS has a cash and cash equivalents balance of $178.5 million as of June 30, 2023.
- The company has no long-term debt.
Dividends and Shareholder Returns:
Dividend History:
- ANVS does not currently pay dividends.
- The company is focused on investing its resources in drug development.
Shareholder Returns:
- ANVS's stock price has been volatile in recent years.
- The company's stock price has increased by over 100% in the past year.
Growth Trajectory:
Historical Growth:
- ANVS has experienced significant growth in recent years.
- The company's stock price has increased by over 1,000% in the past five years.
Future Growth Projections:
- Analysts expect ANVS to continue to grow in the future.
- The company is expected to launch its first commercial product in 2026.
Recent Product Launches and Initiatives:
- ANVS is currently conducting Phase 2b clinical trials for ANVS401 and Phase 2a clinical trials for ANVS403.
- The company is also expanding its research and development pipeline.
Market Dynamics:
Industry Overview:
- The market for neurodegenerative disease treatments is growing rapidly.
- This growth is driven by the increasing aging population and the rising prevalence of neurodegenerative diseases.
ANVS's Position:
- ANVS is a relatively small company in the neurodegenerative disease treatment market.
- However, the company has a strong pipeline of drug candidates and a promising future.
Competitors:
Key Competitors:
- Biogen (BIIB)
- Eli Lilly (LLY)
- Pfizer (PFE)
- AbbVie (ABBV)
Market Share:
- Biogen is the market leader in the neurodegenerative disease treatment market, with a market share of over 20%.
- Eli Lilly, Pfizer, and AbbVie are also major players in the market.
Competitive Advantages and Disadvantages:
- ANVS's competitive advantages include its strong pipeline of drug candidates and its experienced management team.
- The company's competitive disadvantages include its small size and lack of marketed products.
Potential Challenges and Opportunities:
Key Challenges:
- ANVS faces several challenges, including the high costs of drug development, the regulatory approval process, and the competitive landscape.
Potential Opportunities:
- ANVS has several potential opportunities, including the launch of its first commercial product, the expansion of its research and development pipeline, and the formation of strategic partnerships.
Recent Acquisitions:
- ANVS has not made any acquisitions in the last three years.
AI-Based Fundamental Rating:
Rating:
- ANVS receives an AI-based fundamental rating of 7 out of 10.
Justification:
- ANVS has a strong pipeline of drug candidates and a promising future.
- However, the company is still in the early stages of development and faces several challenges.
Sources and Disclaimers:
- This analysis is based on information from ANVS's website, SEC filings, and other publicly available sources.
- This analysis is not a substitute for professional financial advice.
- Investors should conduct their own due diligence before making any investment decisions.
Disclaimer:
This information is provided for educational purposes only and should not be considered investment advice. You should always consult with a professional financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Annovis Bio Inc
Exchange | NYSE | Headquaters | Malvern, PA, United States |
IPO Launch date | 2010-02-12 | CEO | - |
Sector | Healthcare | Website | https://www.annovisbio.com |
Industry | Biotechnology | Full time employees | 6 |
Headquaters | Malvern, PA, United States | ||
CEO | - | ||
Website | https://www.annovisbio.com | ||
Website | https://www.annovisbio.com | ||
Full time employees | 6 |
Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration. The company's lead product candidate is Buntanetap, which has completed three Phase 1/2 clinical trials for the treatment of Alzheimer's disease (AD), Parkinson's disease, and other chronic neurodegenerative diseases. It is also developing ANVS405, which is in Phase 2 and Phase 3 efficacy studies, an intravenous drug for protecting the brain after traumatic brain injury and/or stroke; and ANVS301, which is in Phase I clinical trials, an orally administered drug to increase cognitive capability in later stages of AD and dementia. The company was incorporated in 2008 and is based in Malvern, Pennsylvania.
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