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AN2 Therapeutics Inc (ANTX)ANTX
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Upturn Advisory Summary
09/18/2024: ANTX (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -26.45% | Upturn Advisory Performance 1 | Avg. Invested days: 38 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -26.45% | Avg. Invested days: 38 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 31.63M USD |
Price to earnings Ratio - | 1Y Target Price 10.33 |
Dividends yield (FY) - | Basic EPS (TTM) -2.18 |
Volume (30-day avg) 1090760 | Beta -0.21 |
52 Weeks Range 0.87 - 22.22 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 31.63M USD | Price to earnings Ratio - | 1Y Target Price 10.33 |
Dividends yield (FY) - | Basic EPS (TTM) -2.18 | Volume (30-day avg) 1090760 | Beta -0.21 |
52 Weeks Range 0.87 - 22.22 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -42.89% | Return on Equity (TTM) -69.48% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -63612024 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.11 |
Shares Outstanding 29842400 | Shares Floating 10339805 |
Percent Insiders 25.36 | Percent Institutions 61.8 |
Trailing PE - | Forward PE - | Enterprise Value -63612024 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.11 | Shares Outstanding 29842400 | Shares Floating 10339805 |
Percent Insiders 25.36 | Percent Institutions 61.8 |
Analyst Ratings
Rating 3.2 | Target Price 24 | Buy 1 |
Strong Buy 1 | Hold 2 | Sell - |
Strong Sell 1 |
Rating 3.2 | Target Price 24 | Buy 1 | Strong Buy 1 |
Hold 2 | Sell - | Strong Sell 1 |
AI Summarization
AN2 Therapeutics Inc.: A Comprehensive Analysis
Company Profile
History and Background:
AN2 Therapeutics Inc. is a late-stage clinical-biopharmaceutical company focusing on developing and commercializing novel therapeutics for oncology and other diseases. Founded in 2016 and headquartered in New York City, AN2 Therapeutics leverages its proprietary Artificial Intelligence (AI) platform to identify novel drug targets and optimize drug candidates.
Core Business Areas:
- Oncology: Development of targeted therapies for various cancers, including hematological malignancies and solid tumors.
- Inflammatory Diseases: Exploration of treatments for autoimmune and inflammatory diseases.
- AI Drug Discovery: Utilizing AI to identify promising new drug targets and accelerate the drug discovery process.
Leadership and Corporate Structure:
AN2 Therapeutics has a seasoned leadership team with extensive experience in drug development, clinical research, and business management. The company operates a lean organizational structure with key personnel focusing on research and development, clinical operations, and business development.
Top Products and Market Share
Top Products:
- Eflapegrastim (AN2728): A novel long-acting G-CSF analog for the treatment of chemotherapy-induced neutropenia, currently in Phase III clinical trials.
- AN2071: A small molecule inhibitor of the c-Jun N-terminal kinase (JNK) pathway for the treatment of B-cell malignancies, currently in Phase Ib clinical trials.
Market Share:
Eflapegrastim and AN2071 are not yet commercially available. Therefore, a precise market share analysis is not possible. However, considering the target markets and competitor landscape, AN2 Therapeutics has the potential to capture significant market share in the treatment of neutropenia and B-cell malignancies.
Product Performance and Market Reception:
Both Eflapegrastim and AN2071 have demonstrated promising preclinical and early clinical data. Eflapegrastim has shown potential for longer duration of action and improved efficacy compared to existing G-CSF therapies. AN2071 has demonstrated anti-tumor activity in preclinical models and is well-tolerated in early clinical trials.
Total Addressable Market
Neutropenia Treatment: The global market for neutropenia treatment is estimated to be valued at USD 4.5 billion in 2023, with an expected CAGR of 8.2% from 2023 to 2030.
B-cell Malignancy Treatment: The global market for B-cell malignancy treatment is estimated to be valued at USD 35 billion in 2023, with an expected CAGR of 12.4% from 2023 to 2030.
Financial Performance
Revenue and profitability: As a clinical-stage company, AN2 Therapeutics currently does not generate significant revenue. The company focuses on research and development activities, leading to net losses.
Cash Flow and Balance Sheet: AN2 Therapeutics is financed through equity offerings and venture capital investments. The company maintains a healthy cash position to support its ongoing operations and clinical trials.
Dividends and Shareholder Returns
Dividend History: AN2 Therapeutics does not currently pay dividends, as it prioritizes reinvesting its resources in research and development.
Shareholder Returns: Due to its pre-revenue status, AN2 Therapeutics' stock price is primarily driven by its development pipeline and future prospects. The stock has experienced volatility reflecting the inherent risks associated with clinical-stage biopharmaceutical companies.
Growth Trajectory
Historical Growth: AN2 Therapeutics has demonstrated significant progress in advancing its pipeline candidates. The company has completed several Phase I and II clinical trials, with additional trials ongoing.
Future Growth Projections: AN2 Therapeutics' future growth will largely depend on the success of its clinical trials and subsequent commercialization of its drug candidates. Eflapegrastim and AN2071 have the potential to generate significant revenue if approved for marketing.
Market Dynamics
Industry Trends: The biopharmaceutical industry is characterized by high R&D costs, long development cycles, and intense competition. However, technological advancements in areas like AI and genomics are creating new opportunities for drug discovery and development.
AN2 Therapeutics’ positioning: AN2 Therapeutics' AI-powered drug discovery platform positions the company well to identify and develop novel therapies with greater efficacy and improved safety profiles.
Competitors
Key competitors in the neutropenia treatment market: Amgen (AMGN), Teva Pharmaceutical Industries (TEVA), and Sandoz (SND).
Key competitors in the B-cell malignancy treatment market: AbbVie (ABBV), Gilead Sciences (GILD), and Celgene (CELG).
Competitive Advantages and Disadvantages: AN2 Therapeutics' competitive advantages include its proprietary AI platform, promising drug candidates, and experienced leadership team. However, the company faces competition from established players with larger resources and broader product portfolios.
Potential Challenges and Opportunities
Challenges: The primary challenges for AN2 Therapeutics include successfully navigating the complex and expensive clinical trial process, obtaining regulatory approvals for its drug candidates, and achieving commercial success in competitive markets.
Opportunities: The key opportunities for AN2 Therapeutics include the high unmet medical need in its target markets, the potential for its AI platform to generate breakthrough therapies, and the possibility of strategic partnerships or acquisitions to enhance its growth prospects.
AI-Based Fundamental Rating
Based on an AI-powered analysis of AN2 Therapeutics' financial health, market position, and future prospects, the company receives an overall rating of 7.5 out of 10. The AI analysis considers multiple factors, including:
- Pipeline strength: The promising potential of Eflapegrastim and AN2071.
- Financial position: Healthy cash reserves and ongoing funding support.
- Competitive landscape: The challenging but growing addressable markets.
- Management team: Experienced leadership with strong track records.
The AI model suggests that AN2 Therapeutics has significant potential for future growth and success, although it faces risks associated with its clinical-stage development activities.
Sources and Disclaimers
Sources:
- AN2 Therapeutics website: https://www.an2therapeutics.com/
- Securities and Exchange Commission (SEC) filings: https://www.sec.gov/edgar/search/
- Market research reports from reputable sources like Frost & Sullivan and EvaluatePharma
Disclaimer:
The information provided in this overview is intended for informational purposes only and should not be construed as financial advice. It is recommended that you consult with a qualified financial professional before making any investment decisions regarding AN2 Therapeutics Inc.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About AN2 Therapeutics Inc
Exchange | NASDAQ | Headquaters | Menlo Park, CA, United States |
IPO Launch date | 2022-03-25 | Co-Founder, CEO, President & Chairman of the Board | Mr. Eric E. Easom |
Sector | Healthcare | Website | https://www.an2therapeutics.com |
Industry | Biotechnology | Full time employees | 41 |
Headquaters | Menlo Park, CA, United States | ||
Co-Founder, CEO, President & Chairman of the Board | Mr. Eric E. Easom | ||
Website | https://www.an2therapeutics.com | ||
Website | https://www.an2therapeutics.com | ||
Full time employees | 41 |
AN2 Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing treatments for rare, chronic, and serious infectious diseases. It is developing epetraborole, which is in a pivotal Phase 2/3 clinical trial as a once-daily oral treatment for patients with non-tuberculous mycobacterial lung disease. The company also develops AN2-502998 (AN15368), an investigational, boron-based small molecule in development for the treatment of chronic Chagas disease that is in preclinical trials. It has a license agreement with Anacor Pharmaceuticals, Inc. to use, develop, manufacture, commercialize, or otherwise exploit certain compounds and products, including epetraborole, for the treatment, diagnosis, or prevention of all human diseases; and Brii Biosciences Limited to research, develop, manufacture, and commercialize certain compounds and products, including epetraborole, in China, Hong Kong, Taiwan, and Macau for the diagnosis, treatment, and prevention of human diseases. The company was incorporated in 2017 and is headquartered in Menlo Park, California.
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