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Alumis Inc. Common Stock (ALMS)



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Upturn Advisory Summary
04/01/2025: ALMS (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit 0% | Avg. Invested days 0 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 630.53M USD | Price to earnings Ratio - | 1Y Target Price 32.33 |
Price to earnings Ratio - | 1Y Target Price 32.33 | ||
Volume (30-day avg) 925453 | Beta - | 52 Weeks Range 3.18 - 16.00 | Updated Date 03/25/2025 |
52 Weeks Range 3.18 - 16.00 | Updated Date 03/25/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.48 |
Earnings Date
Report Date 2025-03-20 | When - | Estimate - | Actual -1.7417 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) - | Return on Equity (TTM) - |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 452576269 | Price to Sales(TTM) - |
Enterprise Value 452576269 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding 47218400 | Shares Floating 14737855 |
Shares Outstanding 47218400 | Shares Floating 14737855 | ||
Percent Insiders 1.27 | Percent Institutions 71.3 |
Analyst Ratings
Rating 4.67 | Target Price 32.33 | Buy 2 | Strong Buy 4 |
Buy 2 | Strong Buy 4 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Alumis Inc. Common Stock
Company Overview
History and Background
Alumis, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for autoimmune diseases. Founded in 2021 and privately held, the company leverages its expertise in precision immunology to target the root cause of autoimmune diseases.
Core Business Areas
- Drug Development: Alumis focuses on discovering and developing oral therapies targeting autoimmune diseases with precision. The company is currently developing oral therapies targeting a specific pathway relevant to multiple autoimmune indications.
- Clinical Trials: Alumis conducts clinical trials to evaluate the safety and efficacy of its drug candidates. They are currently in Phase 2 development for their lead program in relapsing multiple sclerosis.
Leadership and Structure
Alumis is led by a team of experienced biopharmaceutical executives. Details of the exact leadership structure are not widely available since the company is privately held.
Top Products and Market Share
Key Offerings
- ESK-001: ESK-001 is Alumis' lead product candidate, an oral small molecule targeting a specific and well-validated autoimmune pathway. It's currently in Phase 2 clinical trials for relapsing multiple sclerosis (RMS). Market share is currently 0% as it is not yet approved. Key competitors are existing MS therapies from Biogen (BIIB), Novartis (NVS), and Roche (RHHBY).
Market Dynamics
Industry Overview
The autoimmune disease market is a large and growing market driven by an increasing prevalence of autoimmune disorders. The pharmaceutical industry is continuously innovating new therapies to improve patient outcomes.
Positioning
Alumis aims to differentiate itself by developing oral therapies with improved efficacy and safety profiles compared to existing treatments. Their focus on precision immunology targets the specific disease pathways while reducing off-target effects.
Total Addressable Market (TAM)
The TAM for autoimmune disease therapies is substantial, estimated to be over $150 billion. Alumis is positioned to capture a significant portion of this market by developing innovative therapies for specific autoimmune indications.
Upturn SWOT Analysis
Strengths
- Novel therapeutic approach
- Experienced management team
- Strong intellectual property portfolio
- Lead candidate in Phase 2 trials
Weaknesses
- Early-stage company
- Limited clinical data
- Dependence on single product candidate
- No products currently on the market
- Privately held and does not share financial information
Opportunities
- Positive clinical trial results
- Partnerships with pharmaceutical companies
- Expansion into new autoimmune indications
- Advancements in diagnostic tools to identify patients for targeted therapies
Threats
- Clinical trial failures
- Competition from established pharmaceutical companies
- Regulatory hurdles
- Patent challenges
- Economic downturn affecting investment in biotechnology
Competitors and Market Share
Key Competitors
- BIIB
- NVS
- RHHBY
Competitive Landscape
Alumis aims to differentiate itself through a precision immunology approach and oral drug delivery. Established competitors have a larger market presence and extensive resources, but Alumis' innovative approach may offer a competitive advantage.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Growth is currently focused on progressing ESK-001 through clinical trials. Future growth depends on clinical trial success and potential partnerships.
Future Projections: Future growth is highly dependent on the successful development and commercialization of ESK-001. Analyst estimates are not publicly available due to Alumis being a private company.
Recent Initiatives: Alumis' recent initiatives include advancing ESK-001 into Phase 2 clinical trials for relapsing multiple sclerosis (RMS).
Summary
Alumis is a clinical-stage biopharmaceutical company with a promising lead candidate in Phase 2 trials for MS. The company's strength lies in its novel therapeutic approach and experienced management. However, it faces risks associated with clinical trial outcomes, competition from established players, and the need for further funding. Success hinges on positive clinical results and strategic partnerships.
Similar Companies
- VIR
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Sources and Disclaimers
Data Sources:
- Company Website
- ClinicalTrials.gov
- Industry Reports
- Market Research Reports
Disclaimers:
The information provided is for informational purposes only and should not be considered as investment advice. The analysis is based on publicly available information and may be subject to change. Market share data is estimated and may not be precise. Investment decisions should be based on thorough research and consultation with a financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Alumis Inc. Common Stock
Exchange NASDAQ | Headquaters South San Francisco, CA, United States | ||
IPO Launch date 2024-06-28 | President, CEO & Chairman Mr. Martin Babler Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 168 | Website https://www.alumis.com |
Full time employees 168 | Website https://www.alumis.com |
Alumis Inc., a clinical stage biopharmaceutical company, focuses on identifying, acquiring, and accelerating the development and commercialization of medicines for autoimmune disorders. The company's clinical asset comprises of ESK-001, an allosteric tyrosine kinase 2 (TYK2) inhibitor which is in Phase 3 clinical trials for the treatment of plaque psoriasis, systemic lupus erythematosus, and non-infectious uveitis; A-005, a central nervous system-penetrant allosteric TYK2 inhibitor which is in Phase 1 clinical trials for neuroinflammatory and neurodegenerative diseases; and interferon regulatory factor 5 (IRF5) which is in preclinical phase to address immune dysfunction. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. The company was incorporated in 2021 and is headquartered in South San Francisco, California.
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