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ALMS
Upturn stock ratingUpturn stock rating

Alumis Inc. Common Stock (ALMS)

Upturn stock ratingUpturn stock rating
$7.24
Delayed price
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PASS
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  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
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*as per simulation
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Upturn Advisory Summary

04/01/2025: ALMS (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit 0%
Avg. Invested days 0
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 630.53M USD
Price to earnings Ratio -
1Y Target Price 32.33
Price to earnings Ratio -
1Y Target Price 32.33
Volume (30-day avg) 925453
Beta -
52 Weeks Range 3.18 - 16.00
Updated Date 03/25/2025
52 Weeks Range 3.18 - 16.00
Updated Date 03/25/2025
Dividends yield (FY) -
Basic EPS (TTM) -3.48

Earnings Date

Report Date 2025-03-20
When -
Estimate -
Actual -1.7417

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -
Return on Equity (TTM) -

Valuation

Trailing PE -
Forward PE -
Enterprise Value 452576269
Price to Sales(TTM) -
Enterprise Value 452576269
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding 47218400
Shares Floating 14737855
Shares Outstanding 47218400
Shares Floating 14737855
Percent Insiders 1.27
Percent Institutions 71.3

Analyst Ratings

Rating 4.67
Target Price 32.33
Buy 2
Strong Buy 4
Buy 2
Strong Buy 4
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Alumis Inc. Common Stock

stock logo

Company Overview

overview logo History and Background

Alumis, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for autoimmune diseases. Founded in 2021 and privately held, the company leverages its expertise in precision immunology to target the root cause of autoimmune diseases.

business area logo Core Business Areas

  • Drug Development: Alumis focuses on discovering and developing oral therapies targeting autoimmune diseases with precision. The company is currently developing oral therapies targeting a specific pathway relevant to multiple autoimmune indications.
  • Clinical Trials: Alumis conducts clinical trials to evaluate the safety and efficacy of its drug candidates. They are currently in Phase 2 development for their lead program in relapsing multiple sclerosis.

leadership logo Leadership and Structure

Alumis is led by a team of experienced biopharmaceutical executives. Details of the exact leadership structure are not widely available since the company is privately held.

Top Products and Market Share

overview logo Key Offerings

  • ESK-001: ESK-001 is Alumis' lead product candidate, an oral small molecule targeting a specific and well-validated autoimmune pathway. It's currently in Phase 2 clinical trials for relapsing multiple sclerosis (RMS). Market share is currently 0% as it is not yet approved. Key competitors are existing MS therapies from Biogen (BIIB), Novartis (NVS), and Roche (RHHBY).

Market Dynamics

industry overview logo Industry Overview

The autoimmune disease market is a large and growing market driven by an increasing prevalence of autoimmune disorders. The pharmaceutical industry is continuously innovating new therapies to improve patient outcomes.

Positioning

Alumis aims to differentiate itself by developing oral therapies with improved efficacy and safety profiles compared to existing treatments. Their focus on precision immunology targets the specific disease pathways while reducing off-target effects.

Total Addressable Market (TAM)

The TAM for autoimmune disease therapies is substantial, estimated to be over $150 billion. Alumis is positioned to capture a significant portion of this market by developing innovative therapies for specific autoimmune indications.

Upturn SWOT Analysis

Strengths

  • Novel therapeutic approach
  • Experienced management team
  • Strong intellectual property portfolio
  • Lead candidate in Phase 2 trials

Weaknesses

  • Early-stage company
  • Limited clinical data
  • Dependence on single product candidate
  • No products currently on the market
  • Privately held and does not share financial information

Opportunities

  • Positive clinical trial results
  • Partnerships with pharmaceutical companies
  • Expansion into new autoimmune indications
  • Advancements in diagnostic tools to identify patients for targeted therapies

Threats

  • Clinical trial failures
  • Competition from established pharmaceutical companies
  • Regulatory hurdles
  • Patent challenges
  • Economic downturn affecting investment in biotechnology

Competitors and Market Share

competitor logo Key Competitors

  • BIIB
  • NVS
  • RHHBY

Competitive Landscape

Alumis aims to differentiate itself through a precision immunology approach and oral drug delivery. Established competitors have a larger market presence and extensive resources, but Alumis' innovative approach may offer a competitive advantage.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Growth is currently focused on progressing ESK-001 through clinical trials. Future growth depends on clinical trial success and potential partnerships.

Future Projections: Future growth is highly dependent on the successful development and commercialization of ESK-001. Analyst estimates are not publicly available due to Alumis being a private company.

Recent Initiatives: Alumis' recent initiatives include advancing ESK-001 into Phase 2 clinical trials for relapsing multiple sclerosis (RMS).

Summary

Alumis is a clinical-stage biopharmaceutical company with a promising lead candidate in Phase 2 trials for MS. The company's strength lies in its novel therapeutic approach and experienced management. However, it faces risks associated with clinical trial outcomes, competition from established players, and the need for further funding. Success hinges on positive clinical results and strategic partnerships.

Similar Companies

  • VIR
  • IMVT
  • ARWR

Sources and Disclaimers

Data Sources:

  • Company Website
  • ClinicalTrials.gov
  • Industry Reports
  • Market Research Reports

Disclaimers:

The information provided is for informational purposes only and should not be considered as investment advice. The analysis is based on publicly available information and may be subject to change. Market share data is estimated and may not be precise. Investment decisions should be based on thorough research and consultation with a financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Alumis Inc. Common Stock

Exchange NASDAQ
Headquaters South San Francisco, CA, United States
IPO Launch date 2024-06-28
President, CEO & Chairman Mr. Martin Babler Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 168
Full time employees 168

Alumis Inc., a clinical stage biopharmaceutical company, focuses on identifying, acquiring, and accelerating the development and commercialization of medicines for autoimmune disorders. The company's clinical asset comprises of ESK-001, an allosteric tyrosine kinase 2 (TYK2) inhibitor which is in Phase 3 clinical trials for the treatment of plaque psoriasis, systemic lupus erythematosus, and non-infectious uveitis; A-005, a central nervous system-penetrant allosteric TYK2 inhibitor which is in Phase 1 clinical trials for neuroinflammatory and neurodegenerative diseases; and interferon regulatory factor 5 (IRF5) which is in preclinical phase to address immune dysfunction. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. The company was incorporated in 2021 and is headquartered in South San Francisco, California.

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