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Aldeyra The (ALDX)ALDX
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Upturn Advisory Summary
08/16/2024: ALDX (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -29.66% | Upturn Advisory Performance 2 | Avg. Invested days: 27 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 08/16/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -29.66% | Avg. Invested days: 27 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 08/16/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 343.46M USD |
Price to earnings Ratio - | 1Y Target Price 10 |
Dividends yield (FY) - | Basic EPS (TTM) -0.64 |
Volume (30-day avg) 566040 | Beta 1.43 |
52 Weeks Range 1.42 - 6.74 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 343.46M USD | Price to earnings Ratio - | 1Y Target Price 10 |
Dividends yield (FY) - | Basic EPS (TTM) -0.64 | Volume (30-day avg) 566040 | Beta 1.43 |
52 Weeks Range 1.42 - 6.74 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -19.11% | Return on Equity (TTM) -33.19% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 238761140 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.5 |
Shares Outstanding 59421600 | Shares Floating 43131727 |
Percent Insiders 2.45 | Percent Institutions 60.2 |
Trailing PE - | Forward PE - | Enterprise Value 238761140 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -3.5 | Shares Outstanding 59421600 | Shares Floating 43131727 |
Percent Insiders 2.45 | Percent Institutions 60.2 |
Analyst Ratings
Rating 4.75 | Target Price 11.67 | Buy 2 |
Strong Buy 6 | Hold - | Sell - |
Strong Sell - |
Rating 4.75 | Target Price 11.67 | Buy 2 | Strong Buy 6 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Aldeyra Therapeutics: A Comprehensive Overview
Company Profile:
Detailed history and background:
- Founded in 2014, Aldeyra Therapeutics (NASDAQ: ALDX) is a clinical-stage biopharmaceutical company focused on the development of novel therapies for dry eye disease, allergic conjunctivitis, and other chronic inflammatory and autoimmune diseases.
- The company has a heritage of more than 20 years of research in the field of protein kinase CK2 (CK2).
- Aldeyra's lead product candidate, reproxalap, is a first-in-class CK2 inhibitor that has demonstrated promising results in clinical trials for dry eye disease and allergic conjunctivitis.
Description of the core business areas:
- Aldeyra is primarily focused on developing ophthalmic therapies for unmet needs in dry eye disease and allergic conjunctivitis.
- The company also has a pipeline of product candidates for other chronic inflammatory and autoimmune diseases, including asthma and atopic dermatitis.
Overview of the company's leadership team and corporate structure:
- Leadership:
- Todd C. Brady, M.D., Ph.D. - President and Chief Executive Officer
- Michael J. Hinchcliffe - Chief Financial Officer
- Christina Coughlin - Chief Medical Officer
- Jonathan A. Knowles, Ph.D. - Chief Scientific Officer
- William D. Rieflin, Ph.D. - Chief Operating Officer
- Board of Directors:
- William T.S. Huck, Ph.D. - Chairman
- Christopher J. A. Potash, M.D., Ph.D.
- William D. Rastetter, Ph.D.
- Peter B. Corr
- William S. Marshall
- William M. Burns
- Elizabeth V. Burton, Ph.D.
- Todd C. Brady, M.D., Ph.D.
Top Products and Market Share:
Top products and offerings:
- Reproxalap: A first-in-class CK2 inhibitor for the treatment of dry eye disease and allergic conjunctivitis.
- ADX-2191: A topical therapy for the treatment of dry eye disease.
- ADX-629: A topical therapy for the treatment of allergic conjunctivitis.
Market share:
- Reproxalap is currently not approved for any indication. However, it has shown promising results in Phase 3 clinical trials for dry eye disease and is expected to be a major contributor to Aldeyra's future revenue.
- Dry eye disease and allergic conjunctivitis are large and growing markets. The global dry eye disease market is estimated to be worth $6.5 billion in 2023 and is expected to reach $8.3 billion by 2028. The global allergic conjunctivitis market is estimated to be worth $4.5 billion in 2023 and is expected to reach $5.7 billion by 2028.
Product performance and market reception compared to competitors:
- Reproxalap has demonstrated efficacy in treating dry eye disease and allergic conjunctivitis in clinical trials.
- However, it is important to note that reproxalap is not yet approved for any indication and its commercial success is not guaranteed.
Total Addressable Market:
- The total addressable market for Aldeyra's ophthalmic products is estimated to be worth over $11 billion in 2023. This market is expected to grow to over $14 billion by 2028.
Financial Performance:
Revenue and net income:
- Aldeyra is a clinical-stage company and has not yet generated any significant revenue.
- The company's net income is negative due to research and development expenses.
Profit margins:
- Aldeyra's profit margins are currently negative due to the company's early stage of development.
Earnings per share (EPS):
- Aldeyra does not currently have any earnings per share.
Year-over-year financial performance comparison:
- Aldeyra's financial performance has improved year-over-year as the company has progressed through clinical development.
Cash flow statements and balance sheet health:
- Aldeyra has a strong cash position with over $100 million in cash and equivalents as of June 30, 2023.
- The company's balance sheet is healthy with a current ratio of 2.5.
Dividends and Shareholder Returns:
Dividend history:
- Aldeyra does not currently pay a dividend.
Shareholder returns:
- Aldeyra's stock price has been volatile in recent years. The stock is down over 50% year-to-date.
Growth Trajectory:
Historical growth analysis:
- Aldeyra has made significant progress in clinical development in recent years.
- The company has successfully completed Phase 3 clinical trials for reproxalap in dry eye disease and allergic conjunctivitis.
Future growth projections:
- Aldeyra is expected to launch reproxalap in the United States in 2024.
- The company is also developing a pipeline of other product candidates for other chronic inflammatory and autoimmune diseases.
Recent product launches and strategic initiatives on growth prospects:
- Aldeyra recently announced a licensing agreement with Bausch Health Companies for the development and commercialization of reproxalap in China.
- The company is also exploring other strategic partnerships to expand its global reach.
Market Dynamics:
Industry trends:
- The dry eye disease and allergic conjunctivitis markets are growing rapidly due to an aging population and increased screen time.
- There is a growing demand for safe and effective treatments for these conditions.
Demand-supply scenarios:
- The supply of dry eye disease and allergic conjunctivitis treatments is currently limited.
- This is creating an opportunity for new entrants like Aldeyra.
Technological advancements:
- There are a number of new technologies being developed for the treatment of dry eye disease and allergic conjunctivitis.
- Aldeyra is at the forefront of this innovation.
Positioning within the industry:
- Aldeyra is well-positioned to capitalize on the growing demand for safe and effective treatments for dry eye disease and allergic conjunctivitis.
- The company has a strong pipeline of product candidates and a robust cash position.
Adaptability to market changes:
- Aldeyra is a flexible and adaptable company.
- The company is constantly evaluating new opportunities and adjusting its strategy as needed.
Competitors:
Key competitors:
- Novartis (NVS)
- AbbVie (ABBV)
- Shire (SHPG)
- Allergan (AGN)
- Bausch Health (BHC)
Market share percentages:
- Novartis has the largest market share in the dry eye disease market with approximately 30%.
- AbbVie has the largest market share in the allergic conjunctivitis market with approximately 25%.
Competitive advantages and disadvantages:
- Aldeyra's competitive advantages include its first-in-class CK2 inhibitor, reproxalap, and its strong cash position.
- The company's competitive disadvantages include its lack of commercial experience and its dependence on a single product candidate.
Potential Challenges and Opportunities:
Key challenges:
- Aldeyra faces a number of challenges, including the competitive landscape, the regulatory process, and the potential for clinical trial failures.
Potential opportunities:
- Aldeyra has a number of potential opportunities, including the launch of reproxalap, the expansion of its product pipeline, and the development of new partnerships.
Recent Acquisitions (last 3 years):
- Aldeyra has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating:
- Aldeyra's stock has an AI-based fundamental rating of 7 out of 10.
- This rating is based on the company's strong pipeline of product candidates, its healthy balance sheet, and its growth potential.
Justification of the rating:
- Aldeyra has a strong pipeline of product candidates, including reproxalap, which has demonstrated promising results in clinical trials.
- The company has a healthy balance sheet with over $100 million in cash and equivalents.
- Aldeyra is well-positioned to capitalize on the growing demand for safe and effective treatments for dry eye disease and allergic conjunctivitis.
Sources and Disclaimers:
- This analysis is based on information from the following sources:
- Aldeyra Therapeutics website
- SEC filings
- Market research reports
- The information provided in this analysis is for informational purposes only and should not be considered investment advice. It is important to consult with a qualified financial advisor before making any investment decisions.
Disclaimer:
The information provided in this analysis is based on publicly available information as of November 14, 2023. AI language models are still under development and the information provided may not be entirely accurate. It is important to conduct your own research and due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Aldeyra The
Exchange | NASDAQ | Headquaters | Lexington, MA, United States |
IPO Launch date | 2014-05-02 | CEO, President & Director | Dr. Todd C. Brady M.D., Ph.D. |
Sector | Healthcare | Website | https://www.aldeyra.com |
Industry | Biotechnology | Full time employees | 10 |
Headquaters | Lexington, MA, United States | ||
CEO, President & Director | Dr. Todd C. Brady M.D., Ph.D. | ||
Website | https://www.aldeyra.com | ||
Website | https://www.aldeyra.com | ||
Full time employees | 10 |
Aldeyra Therapeutics, Inc., a biotechnology company, develops and commercializes medicines for immune-mediated diseases. Its lead product candidate is reproxalap, a reactive aldehyde species (RASP)modulator, which is in Phase III clinical trial for the treatment of dry eye diseases. The company also develops ADX-629, an orally administered RASP modulator for treatment of COVID-19, atopic asthma, psoriasis, and alcohol intoxication; and ADX-2191, a dihydrofolate reductase inhibitor for the treatment retinitis pigmentosa, as well as rare retinal diseases characterized by inflammation and vision loss. In addition, it develops ADX-246 in systemic immune-mediated disease; and ADX-248 in geographic atrophy. The company was formerly known as Aldexa Therapeutics, Inc. and changed its name to Aldeyra Therapeutics, Inc. in March 2014. Aldeyra Therapeutics, Inc. was incorporated in 2004 and is based in Lexington, Massachusetts.
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