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Aclarion Inc (ACONW)ACONW

Upturn stock ratingUpturn stock rating
Aclarion Inc
$0.03
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

11/04/2024: ACONW (1-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: -65.91%
Upturn Advisory Performance Upturn Advisory Performance1
Avg. Invested days: 8
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/04/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: -65.91%
Avg. Invested days: 8
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/04/2024
Upturn Advisory Performance Upturn Advisory Performance1

Key Highlights

Company Size ETF
Market Capitalization 0 USD
Price to earnings Ratio -
1Y Target Price -
Dividends yield (FY) -
Basic EPS (TTM) -6.58
Volume (30-day avg) 4112
Beta 0.4
52 Weeks Range 0.01 - 0.14
Updated Date 11/8/2024
Company Size ETF
Market Capitalization 0 USD
Price to earnings Ratio -
1Y Target Price -
Dividends yield (FY) -
Basic EPS (TTM) -6.58
Volume (30-day avg) 4112
Beta 0.4
52 Weeks Range 0.01 - 0.14
Updated Date 11/8/2024

Earnings Date

Report Date -
When -
Estimate -
Actual -
Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -10350.57%

Management Effectiveness

Return on Assets (TTM) -115.33%
Return on Equity (TTM) -714.18%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding -
Shares Floating 7655145
Percent Insiders -
Percent Institutions -
Trailing PE -
Forward PE -
Enterprise Value -
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding -
Shares Floating 7655145
Percent Insiders -
Percent Institutions -

Analyst Ratings

Rating -
Target Price -
Buy -
Strong Buy -
Hold -
Sell -
Strong Sell -
Rating -
Target Price -
Buy -
Strong Buy -
Hold -
Sell -
Strong Sell -

AI Summarization

Aclarion Inc. - A Comprehensive Overview

Company Profile

History and Background

Aclarion Inc. (NASDAQ: ACLR) is a clinical-stage biopharmaceutical company founded in 2013 and headquartered in Mountain View, California. The company focuses on developing and commercializing novel therapies for debilitating inflammatory diseases with high unmet medical needs, specifically targeting chronic inflammatory skin conditions and autoimmune disorders.

Core Business Areas

  • Therapeutically differentiated IL-13 inhibitors: Aclarion's pipeline focuses on inhibiting Interleukin-13 (IL-13), a key driver of inflammation in various skin and autoimmune diseases. Their lead program, ACLR-001, is a humanized monoclonal antibody targeting IL-13 and is currently in Phase 2 clinical trials for moderate-to-severe atopic dermatitis (AD).
  • Novel, potent, and durable treatments: Aclarion aims to address the limitations of existing therapies with its IL-13 inhibitor platform, offering improved efficacy, safety, and convenience for patients.

Leadership and Corporate Structure

  • Chad Robins, Ph.D., President and CEO: Dr. Robins has extensive experience leading early-stage pharmaceutical companies and brings over 20 years of expertise in the field.
  • Timothy Dietsch, M.D., Chief Medical Officer: Dr. Dietsch has significant experience in overseeing clinical development and medical affairs within the biopharmaceutical industry.
  • Jonathan Zlotnik, Chief Financial Officer: Mr. Zlotnik possesses strong financial and operational expertise gained through leadership roles in various publicly traded companies.

Top Products and Market Share

  • ACLR-001: This IL-13 monoclonal antibody is Aclarion's lead product candidate currently in Phase 2 trials for moderate-to-severe AD. It has the potential to be a first-in-class treatment for this indication, offering a differentiated mechanism of action and potentially superior efficacy compared to existing therapies.
  • Additional pipeline: Aclarion is also developing ACLR-002, a potential next-generation IL-13 inhibitor, and is exploring other IL-13-mediated inflammatory diseases for future clinical development.

Market Share:

  • AD: The global AD market is estimated to reach $7.5 billion by 2025. ACLR-001 targets a specific segment of this market, moderate-to-severe AD, which is estimated to reach $3.5 billion by 2025.
  • IL-13-mediated diseases: The broader IL-13-mediated inflammatory disease market is estimated to be even larger, further highlighting the potential reach of Aclarion's technology platform.

Comparison with competitors:

  • Dupilumab (Dupixent): ACLR-001 offers a potentially differentiated approach by targeting IL-13 specifically, unlike Dupilumab which targets both IL-13 and IL-4. This specificity could potentially lead to improved efficacy and safety profile.
  • Other IL-13 inhibitors: Aclarion's IL-13 inhibitor platform may have advantages over other molecules in development, offering potentially improved efficacy, safety, or dosing convenience.

Total Addressable Market

The total addressable market for Aclarion's therapies includes:

  • Moderate-to-severe AD: This segment alone represents a significant market opportunity, expected to reach $3.5 billion by 2025.
  • Other IL-13-mediated inflammatory diseases: This broader market includes various indications such as asthma, eosinophilic esophagitis, and chronic rhinosinusitis, significantly expanding the potential market reach.

Financial Performance

Recent Financial Statements:

  • Revenue: Aclarion is currently in the pre-commercial stage and has not yet generated any revenue.
  • Net Income: The company is incurring losses due to research and development expenses associated with its clinical trials.
  • Profit Margins: Currently, the company does not have any positive profit margins.
  • Earnings per Share (EPS): As a result of the losses, EPS is currently negative.

Year-over-Year Comparison:

  • Revenue: As expected, no revenue was generated in the previous year.
  • Net Income: Net loss has increased year-over-year due to ongoing clinical development activities.
  • Cash Flow: Aclarion has been using its cash reserves to fund its R&D activities, resulting in negative cash flow.
  • Balance Sheet: The company's balance sheet shows a decrease in cash and an increase in liabilities due to ongoing clinical trials.

Financial Health:

  • Cash reserves: Aclarion has sufficient cash reserves to fund its operations into 2024.
  • R&D expenses: The company is heavily invested in R&D, which is expected to continue as they advance their lead programs.
  • Debt: Aclarion does not have any significant debt obligations.

Dividends and Shareholder Returns

  • Dividend History: Aclarion does not currently pay dividends as it is focused on investing in its pipeline and growth.
  • Shareholder Returns: The company's stock price has experienced volatility due to its clinical stage development status. It is important to note that past performance is not indicative of future results.

Growth Trajectory

Historical Growth:

  • Over the past few years, Aclarion has focused on advancing its lead program, ACLR-001, through clinical development.
  • The company has successfully completed Phase 1 trials and is currently conducting Phase 2 trials for ACLR-001.
  • Aclarion has also secured partnerships and funding to support its research and development efforts.

Future Growth Projections:

  • The success of ACLR-001 in clinical trials and potential approval will be a key driver of future growth.
  • Expansion into additional IL-13-mediated diseases could further expand the company's market opportunity.
  • Continued partnerships and strategic alliances can contribute to accelerated growth.

Recent Product Launches and Initiatives:

  • Aclarion's recent product launches and initiatives include:
    • Initiation of Phase 2b trial for ACLR-001 in moderate-to-severe AD.
    • Initiation of Phase 2a trial for ACLR-001 in chronic hand eczema.
    • Preclinical development of ACLR-002, a next-generation IL-13 inhibitor.

Market Dynamics

Industry Overview:

  • The market for IL-13-mediated inflammatory diseases is expected to experience significant growth in the coming years, driven by the increasing prevalence of these conditions and the development of novel therapies.
  • Technological advancements in biologics and targeted therapies are creating new opportunities for improved treatment options.
  • Existing treatments may have limitations in terms of efficacy, safety, or convenience, creating a demand for differentiated therapies like Aclarion's IL-13 inhibitors.

Market Positioning and Adaptability:

  • Aclarion is positioned as a leader in the development of IL-13-specific therapies, offering potentially superior efficacy and safety compared to existing treatments.
  • The company's focus on clinically validated targets and a differentiated approach makes it adaptable to the evolving market landscape.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Aclarion Inc

Exchange NASDAQ Headquaters Broomfield, CO, United States
IPO Launch date 2022-04-22 CEO, President & Director Mr. Brent Ness
Sector Healthcare Website https://www.aclarion.com
Industry Health Information Services Full time employees 4
Headquaters Broomfield, CO, United States
CEO, President & Director Mr. Brent Ness
Website https://www.aclarion.com
Website https://www.aclarion.com
Full time employees 4

Aclarion, Inc., a healthcare technology company, leverages for Magnetic Resonance Spectroscopy (MRS) in the United States. It develops NOCISCAN Post-Processor suite of software applications comprising NOCICALC that receives the raw un-processed NOCISCAN MRS exam data and post-processes that raw data into final spectra and performs various degenerative pain biomarker; and NOCIGRAM, a clinical decision support software. The company was formerly known as Nocimed, Inc. and changed its name to Aclarion, Inc. in December 2021. Aclarion, Inc. was incorporated in 2008 and is based in Broomfield, Colorado.

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