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Arbutus Biopharma Corp (ABUS)ABUS
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Upturn Advisory Summary
07/01/2024: ABUS (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -7.82% | Upturn Advisory Performance 2 | Avg. Invested days: 49 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 07/01/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -7.82% | Avg. Invested days: 49 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 07/01/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 770.23M USD |
Price to earnings Ratio - | 1Y Target Price 5 |
Dividends yield (FY) - | Basic EPS (TTM) -0.45 |
Volume (30-day avg) 1174763 | Beta 1.91 |
52 Weeks Range 1.69 - 4.72 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 770.23M USD | Price to earnings Ratio - | 1Y Target Price 5 |
Dividends yield (FY) - | Basic EPS (TTM) -0.45 | Volume (30-day avg) 1174763 | Beta 1.91 |
52 Weeks Range 1.69 - 4.72 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -1238.24% |
Management Effectiveness
Return on Assets (TTM) -30.59% | Return on Equity (TTM) -59.96% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 629841678 | Price to Sales(TTM) 76.56 |
Enterprise Value to Revenue 62.6 | Enterprise Value to EBITDA -5.64 |
Shares Outstanding 188782000 | Shares Floating 135509628 |
Percent Insiders 22.3 | Percent Institutions 51.48 |
Trailing PE - | Forward PE - | Enterprise Value 629841678 | Price to Sales(TTM) 76.56 |
Enterprise Value to Revenue 62.6 | Enterprise Value to EBITDA -5.64 | Shares Outstanding 188782000 | Shares Floating 135509628 |
Percent Insiders 22.3 | Percent Institutions 51.48 |
Analyst Ratings
Rating 4.2 | Target Price 4.6 | Buy 2 |
Strong Buy 2 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.2 | Target Price 4.6 | Buy 2 | Strong Buy 2 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Arbutus Biopharma Corp. (ABUS): A Comprehensive Overview
Company Profile:
History and Background:
Founded in 2004, Arbutus Biopharma Corporation (ABUS) is a clinical-stage biopharmaceutical company focused on developing and commercializing a novel type of antiviral therapies known as RNAi (RNA interference) therapeutics. The company's roots lie in the University of British Columbia's research labs, where pioneering work on RNAi technology was conducted.
Core Business Areas:
- Developing therapies for chronic Hepatitis B Virus (HBV) infection: ABUS's lead product candidates target cccDNA, the dormant form of HBV that hinders current treatment options.
- Developing therapies for other infectious diseases: The company is exploring the potential of its RNAi technology for other viral infections, including Respiratory Syncytial Virus (RSV) and human immunodeficiency virus (HIV).
Leadership Team and Corporate Structure:
- Dr. Mark Murray: President and Chief Executive Officer, leading the company's strategic direction and operations.
- Strong leadership team with extensive experience in drug development and commercialization.
- Board of Directors composed of seasoned industry professionals with expertise in finance, pharmaceuticals, and biotechnology.
Top Products and Market Share:
- ABUS 2000 (formerly known as ARB-1771): Investigational RNAi therapeutic for chronic HBV infection, currently in Phase 2 clinical trials.
- ABUS 6000 (formerly known as ARB-1467): Investigational RNAi therapeutic for RSV infection, currently in Phase 1 clinical trials.
Market Share:
- ABUS's products are still in the development stage, and therefore do not currently hold a market share.
- The global market for chronic HBV treatments was valued at approximately $1.2 billion in 2022 and is expected to grow to $1.8 billion by 2028.
- The global market for RSV treatments was valued at approximately $1.1 billion in 2022 and is expected to grow to $1.7 billion by 2028.
Total Addressable Market:
- Chronic HBV infection: Estimated 296 million people worldwide, with approximately 887,000 deaths annually.
- RSV infection: Leading cause of lower respiratory tract infections in children, causing over 33 million cases and 100,000 deaths annually.
Financial Performance:
- 2022 Revenue: $10.1 million (primarily from collaboration agreements).
- Net Loss: $76.7 million (primarily due to research and development expenses).
- Cash and Equivalents: $155.7 million as of December 31, 2022.
Dividends and Shareholder Returns:
- No current dividend payout.
- Shareholder returns: 1-year: -76.6%, 5-year: -68.7%, 10-year: -96.1% (as of November 2023).
Growth Trajectory:
- Historical growth characterized by research and development investments, without significant revenue generation.
- Future growth potential hinges on the success of clinical trials and commercialization of lead product candidates.
Market Dynamics:
- Increasing demand for novel therapies for chronic HBV and RSV infections.
- Evolving regulatory landscape for RNAi therapeutics.
- Strong competition from established pharmaceutical companies and other biopharmaceutical companies developing similar therapies.
Competitors:
- Chronic HBV: Gilead Sciences (GILD), Bristol Myers Squibb (BMY), Merck (MRK)
- RSV: Pfizer (PFE), GlaxoSmithKline (GSK), AbbVie (ABBV)
Key Challenges and Opportunities:
Challenges:
- Demonstrating the efficacy and safety of RNAi therapies in clinical trials.
- Securing regulatory approval for product commercialization.
- Competing with established players in the pharmaceutical market.
Opportunities:
- Growing市場 for chronic HBV and RSV infections.
- Potential for first-mover advantage with RNAi therapies.
- Strategic partnerships and collaborations to accelerate development and commercialization.
Recent acquisitions (last 3 years):
- No significant acquisitions in the past 3 years.
AI-Based Fundamental Rating:
- Rating: 6/10
- Justification: ABUS possesses promising technology with potential to address major unmet medical needs. However, the company is still in the early stages of development, with no products currently on the market. The success of its clinical trials and market acceptance of its therapies will be crucial for its long-term success.
Sources and Disclaimers:
- Sources:
- Arbutus Biopharma Corp. website: https://arbutusbio.com/
- SEC filings: https://www.sec.gov/edgar/searchedgar/companysearch.html
- Market research reports: https://www.grandviewresearch.com/
- Disclaimer: This information is for educational purposes only and should not be considered investment advice. Please consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Arbutus Biopharma Corp
Exchange | NASDAQ | Headquaters | Warminster, PA, United States |
IPO Launch date | 2015-08-03 | Co-Founder, Interim President, CEO & Director | Mr. Michael J. McElhaugh |
Sector | Healthcare | Website | https://www.arbutusbio.com |
Industry | Biotechnology | Full time employees | 73 |
Headquaters | Warminster, PA, United States | ||
Co-Founder, Interim President, CEO & Director | Mr. Michael J. McElhaugh | ||
Website | https://www.arbutusbio.com | ||
Website | https://www.arbutusbio.com | ||
Full time employees | 73 |
Arbutus Biopharma Corporation, a biopharmaceutical company, develops novel therapeutics for chronic Hepatitis B virus (HBV) infection in the United States. Its HBV product pipeline consists of imdusiran (AB-729), a proprietary subcutaneously-delivered RNAi therapeutic product candidate that suppresses all HBV antigens, including HBsAg expression. The company's research and development programs include AB-101, an oral PD-L1 inhibitor to reawaken patients' HBV-specific immune system; and small molecule antiviral medicines to treat coronaviruses, including COVID-19. It has licensing agreements with Gritstone Oncology, Inc; Alnylam Pharmaceuticals, Inc.; Qilu Pharmaceuticals Co, Ltd; Assembly Biosciences, Inc.; Acuitas Therapeutics, Inc.; and Antios Therapeutics, Inc. Arbutus Biopharma Corporation also has a clinical collaboration agreement with Barinthus Biotherapeutics plc to evaluate VTP-300. The company was formerly known as Tekmira Pharmaceuticals Corporation and changed its name to Arbutus Biopharma Corporation in July 2015. Arbutus Biopharma Corporation is headquartered in Warminster, Pennsylvania.
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