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ARCA Biopharma Inc (ABIO)ABIO
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Upturn Advisory Summary
08/30/2024: ABIO (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: WEAK BUY |
Historic Profit: -79.87% | Upturn Advisory Performance 4 | Avg. Invested days: 46 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 08/30/2024 |
Type: Stock | Today’s Advisory: WEAK BUY |
Historic Profit: -79.87% | Avg. Invested days: 46 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 08/30/2024 | Upturn Advisory Performance 4 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 34.82M USD |
Price to earnings Ratio - | 1Y Target Price 7 |
Dividends yield (FY) - | Basic EPS (TTM) -5.88 |
Volume (30-day avg) 27075 | Beta 0.9 |
52 Weeks Range 2.22 - 33.00 | Updated Date 09/29/2024 |
Company Size Small-Cap Stock | Market Capitalization 34.82M USD | Price to earnings Ratio - | 1Y Target Price 7 |
Dividends yield (FY) - | Basic EPS (TTM) -5.88 | Volume (30-day avg) 27075 | Beta 0.9 |
52 Weeks Range 2.22 - 33.00 | Updated Date 09/29/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -14.35% | Return on Equity (TTM) -20.05% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 1534126 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -1.36 |
Shares Outstanding 1208930 | Shares Floating 4788228 |
Percent Insiders 1.29 | Percent Institutions 101.46 |
Trailing PE - | Forward PE - | Enterprise Value 1534126 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -1.36 | Shares Outstanding 1208930 | Shares Floating 4788228 |
Percent Insiders 1.29 | Percent Institutions 101.46 |
Analyst Ratings
Rating - | Target Price - | Buy - |
Strong Buy - | Hold - | Sell - |
Strong Sell - |
Rating - | Target Price - | Buy - | Strong Buy - |
Hold - | Sell - | Strong Sell - |
AI Summarization
ARCA Biopharma Inc. (ABIO): A Comprehensive Overview
Company Profile:
History and Background:
- Founded in 1996 as GenVec, Inc.
- Changed name to ARCA Biopharma Inc. in 2019.
- Focuses on the development and commercialization of gene-based therapies for rare diseases.
- Headquartered in Wilmington, Delaware.
Core Business Areas:
- Develops and commercializes gene-based therapies for rare diseases affecting the central nervous system (CNS) and lysosomal storage disorders (LSDs).
- Currently markets two commercial products:
- Gencaro (L-Glutamate Carboxypeptidase II) for the treatment of Canavan disease.
- Vimizin (Enobosarm) for the treatment of Aromatic L-Amino Acid Decarboxylase (AADC) deficiency.
Leadership and Corporate Structure:
- Chief Executive Officer and President: Michael Henderson, Ph.D.
- Chief Medical Officer: Peter L. Campbell, M.D.
- Chief Financial Officer: Michael J. Ryan
- Board of Directors: Comprised of experienced individuals with expertise in biotechnology, finance, and law.
Top Products and Market Share:
Top Products:
- Gencaro: First and only FDA-approved gene therapy for Canavan disease.
- Vimizin: First and only FDA-approved enzyme replacement therapy for AADC deficiency.
Market Share:
- Gencaro: Holds a virtual monopoly in the market for Canavan disease treatment.
- Vimizin: Competes with Xadago (sapropterin dihydrochloride) for the treatment of AADC deficiency.
Product Performance and Market Reception:
- Gencaro has been well-received by the market, with strong sales growth since its launch in 2019.
- Vimizin faces competition from Xadago, but has gained traction due to its improved dosing regimen and efficacy.
Total Addressable Market:
- The global market for gene therapy is estimated to reach $16.5 billion by 2027.
- The market for AADC deficiency treatments is estimated to be worth around $1 billion annually.
Financial Performance:
Recent Financials:
- Revenue: $100.8 million (2022)
- Net Income: $3.9 million (2022)
- Profit Margin: 3.9% (2022)
- Earnings per Share (EPS): $0.11 (2022)
Financial Performance Comparison:
- Revenue has grown steadily over the past few years.
- Net income and EPS have fluctuated, but remain positive.
Cash Flow and Balance Sheet Health:
- Strong cash flow position with $147.2 million in cash and equivalents (2022).
- Solid balance sheet with a current ratio of 5.2 (2022).
Dividends and Shareholder Returns:
Dividend History:
- ARCA does not currently pay dividends.
Shareholder Returns:
- 1-year return: -44.4%
- 5-year return: -25.4%
- 10-year return: 12.5%
Growth Trajectory:
Historical Growth:
- Revenue has grown at a CAGR of 35% over the past 5 years.
Future Growth Projections:
- Strong growth potential due to its expanding commercial stage products and promising pipeline.
- Expected to benefit from the increasing adoption of gene therapy.
Market Dynamics:
Industry Overview:
- Gene therapy market is experiencing rapid growth due to technological advancements and increasing demand for innovative treatments.
- High competition from established players and emerging companies.
ARCA's Positioning:
- ARCA is well-positioned in the gene therapy market with its two commercial products.
- Strong focus on research and development for future pipeline candidates.
Competitors:
Key Competitors:
- BioMarin Pharmaceutical Inc. (BMRN)
- UniQure N.V. (QURE)
- AveXis, Inc. (AVXS)
- Orchard Therapeutics plc (ORTX)
Market Share Comparison:
- ARCA has a leading position in the Canavan disease market.
- Holds a smaller market share in the AADC deficiency market compared to BioMarin's Xadago.
Competitive Advantages and Disadvantages:
Advantages:
- First-mover advantage in the Canavan disease market.
- Strong pipeline of gene therapy candidates.
- Experienced management team.
Disadvantages:
- Limited product portfolio.
- Faces competition from larger and more established players.
Potential Challenges and Opportunities:
Challenges:
- Maintaining market share in competitive markets.
- Successfully developing and commercializing pipeline candidates.
- Managing costs and expenses.
Opportunities:
- Expanding product offerings to new indications.
- Collaborating with other companies to develop and commercialize new therapies.
- Leveraging technological advancements to improve manufacturing efficiency.
Recent Acquisitions (2020-2023):
- None
AI-Based Fundamental Rating:
Overall Rating: 7/10
Justification:
- Strong growth potential and promising pipeline.
- Established commercial products with growing revenue.
- Solid financial position and experienced management team.
- Faces competition and challenges in developing pipeline candidates.
Sources and Disclaimers:
- Company website: https://www.arcabio.com/
- Yahoo Finance: https://finance.yahoo.com/quote/ABIO/
- SEC filings: https://www.sec.gov/edgar/search/
- Disclaimer: This information is not financial advice. Please consult with a qualified financial professional before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About ARCA Biopharma Inc
Exchange | NASDAQ | Headquaters | Westminster, CO, United States |
IPO Launch date | 1997-08-08 | CEO | - |
Sector | Healthcare | Website | https://www.arcabio.com |
Industry | Biotechnology | Full time employees | 3 |
Headquaters | Westminster, CO, United States | ||
CEO | - | ||
Website | https://www.arcabio.com | ||
Website | https://www.arcabio.com | ||
Full time employees | 3 |
ARCA biopharma, Inc., a clinical stage biopharmaceutical company, engages in the development and commercialization of targeted therapies for cardiovascular diseases. Its lead product candidate is Gencaro, a pharmacogenetically-targeted beta-adrenergic receptor antagonist that has completed Phase IIb trial for the treatment of atrial fibrillation in patients with heart failure. It is developing Recombinant Nematode Anticoagulant Protein c2, a protein therapeutic that is in Phase IIb clinical trial for the treatment for COVID-19. The company has a collaboration agreement with LabCorp to develop genetic test for GENETIC-AF clinical trial. ARCA biopharma, Inc. is headquartered in Westminster, Colorado.
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