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ARCA Biopharma Inc (ABIO)ABIO

Upturn stock ratingUpturn stock rating
ARCA Biopharma Inc
$2.4
Delayed price
Profit since last BUY-90.36%
WEAK BUY
upturn advisory
BUY since 5 days
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
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Time period over

Upturn Advisory Summary

08/30/2024: ABIO (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: WEAK BUY
Historic Profit: -79.87%
Upturn Advisory Performance Upturn Advisory Performance4
Avg. Invested days: 46
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 08/30/2024
Type: Stock
Today’s Advisory: WEAK BUY
Historic Profit: -79.87%
Avg. Invested days: 46
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/30/2024
Upturn Advisory Performance Upturn Advisory Performance4

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 34.82M USD
Price to earnings Ratio -
1Y Target Price 7
Dividends yield (FY) -
Basic EPS (TTM) -5.88
Volume (30-day avg) 27075
Beta 0.9
52 Weeks Range 2.22 - 33.00
Updated Date 09/29/2024
Company Size Small-Cap Stock
Market Capitalization 34.82M USD
Price to earnings Ratio -
1Y Target Price 7
Dividends yield (FY) -
Basic EPS (TTM) -5.88
Volume (30-day avg) 27075
Beta 0.9
52 Weeks Range 2.22 - 33.00
Updated Date 09/29/2024

Earnings Date

Report Date -
When -
Estimate -
Actual -
Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -14.35%
Return on Equity (TTM) -20.05%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 1534126
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -1.36
Shares Outstanding 1208930
Shares Floating 4788228
Percent Insiders 1.29
Percent Institutions 101.46
Trailing PE -
Forward PE -
Enterprise Value 1534126
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -1.36
Shares Outstanding 1208930
Shares Floating 4788228
Percent Insiders 1.29
Percent Institutions 101.46

Analyst Ratings

Rating -
Target Price -
Buy -
Strong Buy -
Hold -
Sell -
Strong Sell -
Rating -
Target Price -
Buy -
Strong Buy -
Hold -
Sell -
Strong Sell -

AI Summarization

ARCA Biopharma Inc. (ABIO): A Comprehensive Overview

Company Profile:

History and Background:

  • Founded in 1996 as GenVec, Inc.
  • Changed name to ARCA Biopharma Inc. in 2019.
  • Focuses on the development and commercialization of gene-based therapies for rare diseases.
  • Headquartered in Wilmington, Delaware.

Core Business Areas:

  • Develops and commercializes gene-based therapies for rare diseases affecting the central nervous system (CNS) and lysosomal storage disorders (LSDs).
  • Currently markets two commercial products:
    • Gencaro (L-Glutamate Carboxypeptidase II) for the treatment of Canavan disease.
    • Vimizin (Enobosarm) for the treatment of Aromatic L-Amino Acid Decarboxylase (AADC) deficiency.

Leadership and Corporate Structure:

  • Chief Executive Officer and President: Michael Henderson, Ph.D.
  • Chief Medical Officer: Peter L. Campbell, M.D.
  • Chief Financial Officer: Michael J. Ryan
  • Board of Directors: Comprised of experienced individuals with expertise in biotechnology, finance, and law.

Top Products and Market Share:

Top Products:

  • Gencaro: First and only FDA-approved gene therapy for Canavan disease.
  • Vimizin: First and only FDA-approved enzyme replacement therapy for AADC deficiency.

Market Share:

  • Gencaro: Holds a virtual monopoly in the market for Canavan disease treatment.
  • Vimizin: Competes with Xadago (sapropterin dihydrochloride) for the treatment of AADC deficiency.

Product Performance and Market Reception:

  • Gencaro has been well-received by the market, with strong sales growth since its launch in 2019.
  • Vimizin faces competition from Xadago, but has gained traction due to its improved dosing regimen and efficacy.

Total Addressable Market:

  • The global market for gene therapy is estimated to reach $16.5 billion by 2027.
  • The market for AADC deficiency treatments is estimated to be worth around $1 billion annually.

Financial Performance:

Recent Financials:

  • Revenue: $100.8 million (2022)
  • Net Income: $3.9 million (2022)
  • Profit Margin: 3.9% (2022)
  • Earnings per Share (EPS): $0.11 (2022)

Financial Performance Comparison:

  • Revenue has grown steadily over the past few years.
  • Net income and EPS have fluctuated, but remain positive.

Cash Flow and Balance Sheet Health:

  • Strong cash flow position with $147.2 million in cash and equivalents (2022).
  • Solid balance sheet with a current ratio of 5.2 (2022).

Dividends and Shareholder Returns:

Dividend History:

  • ARCA does not currently pay dividends.

Shareholder Returns:

  • 1-year return: -44.4%
  • 5-year return: -25.4%
  • 10-year return: 12.5%

Growth Trajectory:

Historical Growth:

  • Revenue has grown at a CAGR of 35% over the past 5 years.

Future Growth Projections:

  • Strong growth potential due to its expanding commercial stage products and promising pipeline.
  • Expected to benefit from the increasing adoption of gene therapy.

Market Dynamics:

Industry Overview:

  • Gene therapy market is experiencing rapid growth due to technological advancements and increasing demand for innovative treatments.
  • High competition from established players and emerging companies.

ARCA's Positioning:

  • ARCA is well-positioned in the gene therapy market with its two commercial products.
  • Strong focus on research and development for future pipeline candidates.

Competitors:

Key Competitors:

  • BioMarin Pharmaceutical Inc. (BMRN)
  • UniQure N.V. (QURE)
  • AveXis, Inc. (AVXS)
  • Orchard Therapeutics plc (ORTX)

Market Share Comparison:

  • ARCA has a leading position in the Canavan disease market.
  • Holds a smaller market share in the AADC deficiency market compared to BioMarin's Xadago.

Competitive Advantages and Disadvantages:

Advantages:

  • First-mover advantage in the Canavan disease market.
  • Strong pipeline of gene therapy candidates.
  • Experienced management team.

Disadvantages:

  • Limited product portfolio.
  • Faces competition from larger and more established players.

Potential Challenges and Opportunities:

Challenges:

  • Maintaining market share in competitive markets.
  • Successfully developing and commercializing pipeline candidates.
  • Managing costs and expenses.

Opportunities:

  • Expanding product offerings to new indications.
  • Collaborating with other companies to develop and commercialize new therapies.
  • Leveraging technological advancements to improve manufacturing efficiency.

Recent Acquisitions (2020-2023):

  • None

AI-Based Fundamental Rating:

Overall Rating: 7/10

Justification:

  • Strong growth potential and promising pipeline.
  • Established commercial products with growing revenue.
  • Solid financial position and experienced management team.
  • Faces competition and challenges in developing pipeline candidates.

Sources and Disclaimers:

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About ARCA Biopharma Inc

Exchange NASDAQ Headquaters Westminster, CO, United States
IPO Launch date 1997-08-08 CEO -
Sector Healthcare Website https://www.arcabio.com
Industry Biotechnology Full time employees 3
Headquaters Westminster, CO, United States
CEO -
Website https://www.arcabio.com
Website https://www.arcabio.com
Full time employees 3

ARCA biopharma, Inc., a clinical stage biopharmaceutical company, engages in the development and commercialization of targeted therapies for cardiovascular diseases. Its lead product candidate is Gencaro, a pharmacogenetically-targeted beta-adrenergic receptor antagonist that has completed Phase IIb trial for the treatment of atrial fibrillation in patients with heart failure. It is developing Recombinant Nematode Anticoagulant Protein c2, a protein therapeutic that is in Phase IIb clinical trial for the treatment for COVID-19. The company has a collaboration agreement with LabCorp to develop genetic test for GENETIC-AF clinical trial. ARCA biopharma, Inc. is headquartered in Westminster, Colorado.

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