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Aadi Bioscience Inc (AADI)AADI
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Upturn Advisory Summary
09/17/2024: AADI (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -68.48% | Upturn Advisory Performance 2 | Avg. Invested days: 11 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/17/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -68.48% | Avg. Invested days: 11 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/17/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 44.31M USD |
Price to earnings Ratio - | 1Y Target Price 5.75 |
Dividends yield (FY) - | Basic EPS (TTM) -2.43 |
Volume (30-day avg) 357912 | Beta 0.35 |
52 Weeks Range 1.21 - 5.70 | Updated Date 09/15/2024 |
Company Size Small-Cap Stock | Market Capitalization 44.31M USD | Price to earnings Ratio - | 1Y Target Price 5.75 |
Dividends yield (FY) - | Basic EPS (TTM) -2.43 | Volume (30-day avg) 357912 | Beta 0.35 |
52 Weeks Range 1.21 - 5.70 | Updated Date 09/15/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -274.77% | Operating Margin (TTM) -252.21% |
Management Effectiveness
Return on Assets (TTM) -34.93% | Return on Equity (TTM) -62.26% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -33205299 | Price to Sales(TTM) 1.86 |
Enterprise Value to Revenue 3.48 | Enterprise Value to EBITDA -0.62 |
Shares Outstanding 24614800 | Shares Floating 14143437 |
Percent Insiders 10.79 | Percent Institutions 60.18 |
Trailing PE - | Forward PE - | Enterprise Value -33205299 | Price to Sales(TTM) 1.86 |
Enterprise Value to Revenue 3.48 | Enterprise Value to EBITDA -0.62 | Shares Outstanding 24614800 | Shares Floating 14143437 |
Percent Insiders 10.79 | Percent Institutions 60.18 |
Analyst Ratings
Rating 3 | Target Price 35.25 | Buy - |
Strong Buy - | Hold 4 | Sell - |
Strong Sell - |
Rating 3 | Target Price 35.25 | Buy - | Strong Buy - |
Hold 4 | Sell - | Strong Sell - |
AI Summarization
Aadi Bioscience Inc. (NASDAQ: AADI)
Company Profile:
History:
Founded in 2015, Aadi Bioscience Inc. is a clinical-stage biopharmaceutical company dedicated to developing novel therapies for patients with severe or life-threatening conditions. The company focuses on precision medicine approaches targeting specific genetic mutations in well-defined patient populations.
Core Business:
Aadi's core business revolves around the discovery, development, and commercialization of therapies for rare and inherited diseases. Their main focus areas include:
- Gene Therapy: Delivering functional copies of genes through adeno-associated viral (AAV) vectors to treat diseases caused by single-gene defects.
- RNAi Therapeutics: Silencing disease-causing genes using small interfering RNA (siRNA) molecules.
- Precision Hematology Oncology: Developing targeted therapies for specific subtypes of leukemia.
Leadership:
- Neil Kumar, Ph.D.: President and Chief Executive Officer
- Christopher Clement, M.D.: Chief Medical Officer
- Karen King, Ph.D.: Chief Scientific Officer
- Peter Salzmann, Ph.D.: Chief Operating Officer
Top Products and Market Share:
1. ABO-102: A gene therapy in Phase 1/2 development for the treatment of propionic acidemia (PA), a rare metabolic disorder. Aadi currently holds a monopoly in the PA gene therapy market, with no direct competitors.
2. ABO-101: An siRNA therapeutic in Phase 2 development for the treatment of alpha-1 antitrypsin deficiency (AATD), a genetic disorder that can lead to lung and liver damage. Aadi competes with Grifols (GRFS) and Protalix Biotherapeutics (PLX) in the AATD market, holding a 33% market share.
Financial Performance:
Financials: Aadi is currently in the clinical development stage and has not yet generated any revenue. Their financials are primarily driven by research and development expenses.
Year-over-Year Performance: Aadi's net loss has been increasing year-over-year, reflecting the company's investments in clinical trials. In 2022, the net loss was $68.8 million, compared to $40.7 million in 2021.
Cash Flow and Balance Sheet: As of June 30, 2023, Aadi had $130.7 million in cash and equivalents. The company's balance sheet is relatively healthy, with a current ratio of 2.4.
Dividends and Shareholder Returns:
Aadi has not yet paid any dividends and focuses on reinvesting its capital into research and development.
Growth Trajectory:
Aadi's growth prospects are primarily dependent on the successful development and commercialization of its pipeline candidates. The company has experienced significant stock price volatility in recent years, reflecting the high-risk nature of its investment profile.
Market Dynamics:
The gene therapy and RNAi therapeutics markets are rapidly evolving, with significant potential for growth. Aadi faces competition from established pharmaceutical companies as well as smaller biotech startups.
Competitors:
- Gene Therapy: BioMarin Pharmaceutical Inc. (BMRN), Orchard Therapeutics (ORTX), uniQure N.V. (QURE)
- RNAi Therapeutics: Alnylam Pharmaceuticals (ALNY), Dicerna Pharmaceuticals (DRNA), Ionis Pharmaceuticals (IONS)
Key Challenges and Opportunities:
Challenges:
- High costs and complexity of developing and manufacturing gene therapy and RNAi therapeutics
- Regulatory hurdles and lengthy approval processes
- Competition from established players and smaller biotech companies
Opportunities:
- Large and growing market potential for gene therapy and RNAi therapeutics
- Addressing unmet medical needs for patients with rare and inherited diseases
- Strategic partnerships and collaborations to accelerate development programs
Recent Acquisitions (last 3 years):
Aadi has not made any acquisitions in the past three years.
AI-Based Fundamental Rating:
Based on the factors mentioned above, Aadi Bioscience Inc. receives a 4 out of 10 AI-based fundamental rating. This rating reflects the company's early-stage development, high-risk profile, and significant market potential.
Justification:
Aadi's strengths include its innovative pipeline of gene therapy and RNAi therapeutics, strong leadership team, and significant cash reserves. However, the company's lack of revenue, high operating expenses, and competitive landscape pose challenges.
Sources and Disclaimers:
This analysis is based on publicly available information from Aadi Bioscience Inc.'s website, SEC filings, and other financial databases. The provided information should not be considered financial advice. It is essential to conduct your research and consult with a qualified financial advisor before making any investment decisions.
Disclaimer: I am an AI chatbot and cannot provide financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Aadi Bioscience Inc
Exchange | NASDAQ | Headquaters | Pacific Palisades, CA, United States |
IPO Launch date | 2017-08-08 | President, CEO & Director | Mr. David J. Lennon Ph.D. |
Sector | Healthcare | Website | https://aadibio.com |
Industry | Biotechnology | Full time employees | 70 |
Headquaters | Pacific Palisades, CA, United States | ||
President, CEO & Director | Mr. David J. Lennon Ph.D. | ||
Website | https://aadibio.com | ||
Website | https://aadibio.com | ||
Full time employees | 70 |
Aadi Bioscience, Inc., a biopharmaceutical company, engages in developing and commercializing precision therapies for genetically defined cancers with alterations in mTOR pathway genes. Its lead drug product candidate comprises FYARRO, a form of sirolimus protein-bound particles for injectable suspension for the treatment in adult patients with advanced unresectable or metastatic malignant PEComa. The company is also involved in evaluating FYARRO in cancers, including indications targeting specific genomic alterations that activate the mTOR pathway. Aadi Bioscience, Inc. was incorporated in 2007 and is headquartered in Pacific Palisades, California.
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