
Cancel anytime
- Chart
- Upturn Summary
- Highlights
AI Summary
- About
SPDR® S&P Biotech ETF (XBI)



- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- Pass (Skip investing)


(see disclosures)
- ALL
- YEAR
- MONTH
- WEEK
Upturn Advisory Summary
02/20/2025: XBI (3-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type ETF | Historic Profit 9.45% | Avg. Invested days 50 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | ETF Returns Performance ![]() |
![]() ![]() | ![]() ![]() |
Key Highlights
Volume (30-day avg) 9389537 | Beta 0.95 | 52 Weeks Range 81.02 - 105.47 | Updated Date 02/22/2025 |
52 Weeks Range 81.02 - 105.47 | Updated Date 02/22/2025 |
AI Summary
US ETF SPDR® S&P Biotech ETF Summary
Profile:
The SPDR® S&P Biotech ETF (XBI) is an exchange-traded fund that tracks the S&P Biotechnology Select Industry Index. This index comprises leading US biotechnology companies involved in research, development, and commercialization of drugs, medical devices, and other healthcare products. The ETF predominantly invests in large-cap companies, with approximately 75% of its portfolio allocated to this segment.
Objective:
The primary objective of XBI is to provide investors with exposure to the performance of the US biotechnology sector through a single investment instrument. It aims to track the benchmark index closely, offering diversification across various companies within the industry.
Issuer:
The ETF is issued by State Street Global Advisors (SSgA), a leading asset management firm with over $4 trillion in assets under management. SSgA boasts a strong reputation in the financial industry, known for its experience and expertise in managing various investment products, including ETFs.
Market Share:
XBI is the largest and most actively traded biotechnology ETF in the US, with a market share of over 80%. This significant share reflects the ETF's established position within the sector and investor confidence in its management.
Total Net Assets:
As of November 2023, XBI has over $15 billion in total net assets, indicating a substantial investment base and popularity among investors.
Moat:
XBI's competitive advantages include:
- Size and Liquidity: Leading market share and high trading volume ensure easy entry and exit for investors.
- Reputable Issuer: SSgA's experience and expertise inspire investor trust and confidence.
- Transparent Management: Clear and detailed information regarding holdings and performance is readily available.
Financial Performance:
XBI has historically delivered strong returns, outperforming the broader market. However, the ETF's performance can be volatile, reflecting the inherent risks associated with the biotechnology sector.
Benchmark Comparison:
XBI has consistently outperformed its benchmark index, the S&P 500, over various time horizons, demonstrating its effectiveness in tracking and exceeding market performance within the biotechnology sector.
Growth Trajectory:
The biotechnology sector is experiencing significant growth, driven by technological advancements and rising healthcare demand. XBI is well-positioned to benefit from this trend, potentially offering investors substantial capital appreciation opportunities.
Liquidity:
XBI exhibits high liquidity, with an average daily trading volume exceeding 20 million shares. This robust trading activity ensures efficient buying and selling opportunities for investors. The bid-ask spread is relatively narrow, indicating low transaction costs.
Market Dynamics:
Factors influencing XBI's market environment include:
- FDA approvals: New drug and treatment approvals can significantly impact individual companies and the overall biotech sector.
- Clinical trial outcomes: Positive results from clinical trials can drive stock prices higher, while negative outcomes can lead to significant losses.
- Economic conditions: Economic downturns can negatively impact healthcare spending and investment in the biotech sector.
Competitors:
Key competitors include iShares Biotechnology ETF (IBB) and VanEck Biotech ETF (BBH). However, XBI remains the dominant player in the space, with the largest market share and trading volume.
Expense Ratio:
XBI's expense ratio is 0.35%, which is considered relatively low for a sector-specific ETF. This translates to lower costs for investors seeking exposure to the biotechnology industry.
Investment Approach and Strategy:
XBI employs a passive investment strategy, replicating the holdings and performance of the S&P Biotechnology Select Industry Index. The ETF primarily invests in large-cap biotechnology companies, with a diversified portfolio across various sub-segments.
Key Points:
- Leading ETF in the biotechnology sector with over $15 billion in AUM.
- Tracks the S&P Biotechnology Select Industry Index, providing diversified exposure to the US biotech industry.
- Strong historical performance, outperforming both the benchmark index and broader market.
- High liquidity and relatively low expense ratio.
- Suitable for investors seeking targeted exposure to the growing biotechnology sector and its potential for capital appreciation.
Risks:
- High volatility: The biotechnology sector is inherently volatile, leading to potential fluctuations in the ETF's value.
- Market risks: Factors such as regulatory changes, clinical trial outcomes, and economic conditions can negatively impact the industry and the ETF's performance.
- Concentration risk: XBI's focus on large-cap companies limits its exposure to smaller, potentially high-growth firms within the sector.
Who Should Consider Investing:
XBI is appropriate for investors with a long-term investment horizon and risk tolerance who:
- Believe in the long-term growth potential of the biotechnology industry.
- Seek diversified exposure to the sector through a single instrument.
- Can withstand potential volatility associated with the sector
Fundamental Rating Based on AI:
Based on an AI-based rating system, XBI receives a score of 8 out of 10. This rating considers factors such as the ETF's strong market position, diversified holdings, competitive advantages, and potential for future growth within the biotechnology sector.
Resources and Disclaimers:
This analysis utilizes data from the following sources:
- SSgA website: https://www.spdrfundsaustralia.com.au/etfs/us-etfs/spdr-sp-biotechnology-etf.info
- Yahoo Finance: https://finance.yahoo.com/quote/XBI/
- ETF.com: https://www.etf.com/XBI
Disclaimer: This information is for informational purposes only and should not be considered investment advice. It is essential to consult with a qualified financial professional before making any investment decisions.
About SPDR® S&P Biotech ETF
Exchange NYSE ARCA | Headquaters - | ||
IPO Launch date - | CEO - | ||
Sector - | Industry - | Full time employees - | Website |
Full time employees - | Website |
In seeking to track the performance of the S&P Biotechnology Select Industry Index (the index), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index (S&P TMI).
Note: This website is maintained by Upturn Corporation, which is an investment adviser registered with the U.S. Securities and Exchange Commission. Such registration does not imply a certain level of skill or training. Investing in securities has risks. Past performance is no guarantee of future returns. No assurance is provided as to any particular investment return, and you may lose money using our services. You are strongly advised to consult appropriate counsel before making any investments in companies you learn about through our services. You should obtain appropriate legal, tax, investment, accounting, and other advice that takes into account your investment portfolio and overall financial situation. You are solely responsible for conducting due diligence on a potential investment. We do not affect trades for you. You will select your own broker through which to transact. Investments are not FDIC insured, they are not guaranteed, and they may lose value. Please see the Privacy Policy, Terms of Use, and Disclosure for more information.